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Weak immune status, and not HIV infection affects cavity prevalence in children

Recent studies indicate HIV infection heightens the risk of dental cavities - but a Rutgers researcher has found evidence that the risk of cavities comes not from HIV itself but from a weakened immune system, which could be caused by other diseases.

16 Jul 2020

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

In a recent bioRxiv study, an ad hoc multi-institutional research team from the US shows that a novel hormone receptor modulator PT150 has unique and possibly additive antiviral and immunomodulatory effects – highlighting its potential role in the treatment and prophylaxis of coronavirus disease (COVID-19).

14 Jul 2020

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Two new studies led by Renuka Iyer, MD, Section Chief for Gastrointestinal Oncology at Roswell Park Comprehensive Cancer Center, highlight possible new treatment options for patients with neuroendocrine tumors (NETs) - a rare and hard-to-treat cancer.

14 Jul 2020

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

Researchers from the National Institutes of Health (NIH) and Cornell University in the U.S. just described several new inhibitors of human coronavirus spike proteins by screening a library of approved drugs with SARS-S and MERS-S pseudotyped particle entry assays. Their exciting findings are currently available on the bioRxiv preprint server.

13 Jul 2020

McLean Hospital study compares the costs and benefits of esketamine

A paper authored by researchers from McLean Hospital has determined that esketamine, a nasal spray to treat severe depression, is currently too expensive for widespread use.

13 Jul 2020

Upcoming phase II study to discover personalized therapy for patients at high risk for breast cancer relapse

Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women's blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative breast cancer are critical indicators for the prediction of disease recurrence and disease-free survival.

10 Jul 2020

Asthma sufferers can use inhalers amid COVID-19 concerns

The benefits of using inhalers and nebulizers containing steroids outweigh the risks despite warnings to the contrary during the COVID-19 pandemic, a study by University of Huddersfield researchers has found.

9 Jul 2020

High Court allows employers to opt out of ACA’s mandate on birth control coverage

The Supreme Court Wednesday settled — at least for now — a decade's worth of litigation over the women's health provisions of the Affordable Care Act, ruling 7-2 that employers with a "religious or moral objection" to providing contraceptive coverage to their employees may opt out without penalty.

8 Jul 2020

Innovative clinical trial platform launched to accelerate testing of COVID-19 drugs

The University of Liverpool, Liverpool School of Tropical Medicine and Southampton Clinical Trials Unit announced this week that they have launched their innovative COVID-19 drug testing platform, AGILE.

8 Jul 2020

New technology can rapidly disrupt existing biofilms that account for chronic diseases

Chronic and recurrent bacterial diseases are treatment-resistant due to the ability of the pathogens to establish biofilms, which act as fortresses built of extracellular DNA and proteins to protect populations of the bacteria.

8 Jul 2020

Unique nanoparticle can reduce side effects, increase the effectiveness of cancer treatment

A unique nanoparticle to deliver a localized cancer treatment inhibits tumor growth in mice, according to a team of Penn State researchers.

8 Jul 2020

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

A pre-exposure prophylaxis (PrEP) regimen containing an investigational long-acting form of the HIV drug cabotegravir injected once every 8 weeks was more effective than daily oral Truvada at preventing HIV acquisition among cisgender men who have sex with men and transgender women who have sex with men in a clinical trial sponsored by the National Institutes of Health.

7 Jul 2020

Researchers develop peptides for treating gastrointestinal disorders

The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn's disease.

7 Jul 2020

$5 million gift aims to propel Lyme disease research and education

To the Fairbairns, the symptoms--debilitating fatigue, joint pain, cognitive problems--were as worrisome as they were mystifying. All four members of the family had them.

6 Jul 2020

Food sellers across Sub-Saharan Africa are using toxic chemicals to improve the look of meat, fish

Toxic chemicals are being used by food sellers across Sub-Saharan Africa to improve the look of meat and fish, scientists and food inspectors say, putting the health of millions at risk.

3 Jul 2020

Bees-Haus method of cell therapy for treating urethral stricture receives Japanese patent

Treating male urethral stricture with the patient’s own buccal mucosal cells, encapsulated in a polymer scaffold as carrier, has been granted a patent in Japan.

3 Jul 2020

New study provides novel insight into the evolution of mammals

Infant marsupials and monotremes use a connection between their ear and jawbones shortly after birth to enable them to drink their mothers' milk, new findings in eLife reveal.

1 Jul 2020

Study identifies the cause of blood clotting in Covid-19 patients

One of the major mysteries in treating patients with Covid-19 is the frequent development of blood clots that can subsequently damage their organs and sometimes be fatal.

1 Jul 2020

Oral hygiene and severity of COVID-19 – the connection

Their study titled, “Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?” was published in the latest issue of the journal British Dental Journal.

30 Jun 2020

Study links unexpected hospital stays to negative outcomes in head and neck cancer patients

Patients who were unexpectedly hospitalized for dehydration, fever or other ailments while undergoing radiation treatment for head and neck cancers were at a higher risk for less favorable outcomes, a new study from Roswell Park Comprehensive Cancer Center reports.

30 Jun 2020

Oral News and Research

Weak immune status, and not HIV infection affects cavity prevalence in children

Investigational antidepressant PT150 shows antiviral activity against SARS-CoV-2

Two new studies highlight possible treatment options for patients with neuroendocrine tumors

Study identifies three novel broad-spectrum SARS-CoV-2 cell entry inhibitors

McLean Hospital study compares the costs and benefits of esketamine

Upcoming phase II study to discover personalized therapy for patients at high risk for breast cancer relapse

Asthma sufferers can use inhalers amid COVID-19 concerns

High Court allows employers to opt out of ACA’s mandate on birth control coverage

Innovative clinical trial platform launched to accelerate testing of COVID-19 drugs

New technology can rapidly disrupt existing biofilms that account for chronic diseases

Unique nanoparticle can reduce side effects, increase the effectiveness of cancer treatment

NIH study: Long-acting form of HIV prevention drug more effective than daily oral pill

Researchers develop peptides for treating gastrointestinal disorders

$5 million gift aims to propel Lyme disease research and education

Food sellers across Sub-Saharan Africa are using toxic chemicals to improve the look of meat, fish

Bees-Haus method of cell therapy for treating urethral stricture receives Japanese patent

New study provides novel insight into the evolution of mammals

Study identifies the cause of blood clotting in Covid-19 patients

Oral hygiene and severity of COVID-19 – the connection

Study links unexpected hospital stays to negative outcomes in head and neck cancer patients

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