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Fathers more likely to transmit spontaneous mutations to children with ASDs

Researchers have turned up a new clue to the workings of a possible environmental factor in autism spectrum disorders (ASDs): fathers were four times more likely than mothers to transmit tiny, spontaneous mutations to their children with the disorders. Moreover, the number of such transmitted genetic glitches increased with paternal age. The discovery may help to explain earlier evidence linking autism risk to older fathers.

5 Apr 2012

BIND presents results from BIND-014 Phase 1 trial on solid tumors at AACR 2012

BIND Biosciences, a clinical-stage biopharmaceutical company developing a new class of highly selective targeted therapeutics called Accurins, announced today the presentation of late-breaker clinical data for BIND-014, the lead drug candidate within a new class of targeted therapeutics that are programmed to concentrate at tumors, at the American Association for Cancer Research (AACR) 2012 Annual Meeting.

5 Apr 2012

Aberrations in translation regulators linked with hormone receptor-positive breast cancer survival

Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR Annual Meeting 2012.

2 Apr 2012

Researchers discover MicroRNAs as new switch of adipose cell development

Hunger has always threatened mankind. This makes it unsurprising that human bodies attempt to store all surplus nourishment in adipose tissue. In developed countries, this life-saving craving is turning into a problem and obesity—adiposity—is turning into a danger. Why, though, does excess fat the body ill? How does fat trigger diabetes? And can these superfluous fat reserves be turned into warmth and just as well burnt?

30 Mar 2012

ACCR designates Georgetown student as early-career scientist

David A. Solomon, who will graduate from Georgetown University School of Medicine this year with M.D. and Ph.D. degrees, has been designated one of four outstanding early-career scientists by the American Association for Cancer Research (AACR) -- a highly prestigious honor. Solomon will present his work at a special symposium, Future Leaders in Basic Cancer Research, on April 2nd at the AACR Annual Meeting 2012 in Chicago.

28 Mar 2012

UM completes most extensive full vascularized composite allograft to date

The University of Maryland released details today of the most extensive full face transplant completed to date, including both jaws, teeth, and tongue.

28 Mar 2012

Multifaceted intervention improves use of evidence-based medicines

Among patients with acute coronary syndromes (such as heart attack or unstable angina) treated at public hospitals in Brazil, implementation of a multifaceted intervention that included educational materials, checklists and reminders resulted in improvement in the use of evidence-based medicines during the first 24 hours of hospitalization, according to a study appearing in JAMA.

26 Mar 2012

Top SPRG priorities for future NINDS stroke rehabilitation research

In 2011, the National Institute of Neurological Disorders and Stroke (NINDS) convened the Stroke Progress Review Group (SPRG) to conduct a final 10-year review of the state of stroke research.

26 Mar 2012

A rare forum on stem cell biology, engineering and clinical translation

On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy.

22 Mar 2012

RBCC's new agreement with n3D could help develop stem-cell therapies

As global demand for innovative new stem-cell therapies grows by the day, Rainbow BioSciences' new agreement with n3D Biosciences could help to bring these therapies to market faster than ever before.

19 Mar 2012

QB3 renews and expands three-year agreement with Pfizer

The California Institute for Quantitative Biosciences (QB3) has renewed and expanded a three-year agreement with Pfizer Inc. to collaborate on research projects at the University of California with the potential to transform world-class science into better medicine.

17 Mar 2012

Novel sensor selectively screens single molecules passing through nanopores

A novel type of sensor, based on nanometer-scale pores in a semiconductor membrane, is a step closer to practical use in applications such as analyzing the protein contents of a single cell. Researchers pioneering single-molecule nanopore sensor technology at the Technische Universit-t M-nchen (TUM) have shown its potential through a succession of experiments over the past few years.

16 Mar 2012

Merck announces collaboration to create Calibr for early-stage translational research

Merck, known outside the United States and Canada as MSD, today announced a collaboration to create the California Institute for Biomedical Research (Calibr), an independent, not-for-profit organization (501c3) established to accelerate the translation of basic biomedical research into innovative, new medicines to treat disease.

16 Mar 2012

Keeneland Conference to take place from April 17-19 in Lexington

Prominent health leaders representing the public, private and nonprofit sectors will speak next month at the 2012 Keeneland Conference, sponsored by the National Coordinating Center for Public Health Services and Systems Research which is housed at the University of Kentucky College of Public Health and funded by the Robert Wood Johnson Foundation.

16 Mar 2012

New national effort to accelerate development of therapies for neurological diseases

The National Institute for Neurological Disorders and Stroke (NINDS) has selected Columbia University College of Physicians and Surgeons and Weill Cornell Medical College to participate in a new national effort to accelerate the development of therapies for people with neurological diseases.

14 Mar 2012

AACN awards $50,000 Impact Research Grant to Duke nursing professor

The American Association of Critical-Care Nurses (AACN) recently awarded a $50,000 AACN Impact Research Grant to Brigit Carter, RN, PhD, MSN, CCRN, assistant clinical professor at Duke University School of Nursing, Durham, N.C., to study feeding intolerance in preterm infants.

14 Mar 2012

AACN awards $50,000 grant to nursing researcher

The American Association of Critical-Care Nurses (AACN) recently awarded a $50,000 AACN Impact Research Grant to Jean Anne Connor, RN, DNSc, CPNP, director of nursing research in the cardiovascular program at Children's Hospital Boston.

14 Mar 2012

Biomedical research advances through new Australian Institute

The Institute of Biomedical Engineering and Technology (BMET) will be officially opened this evening at the University of Sydney, and will significantly advance this highly multidisciplinary research for life sciences and medicine.

14 Mar 2012

Lowering HbA1c cutoffs increases health benefits of type 2 diabetes preventive interventions

The American Diabetes Association recommends hemoglobin A1c (HbA1c) testing as one basis for identifying diabetes and prediabetes.

13 Mar 2012

Scientists believe that ageing can be programmed in the womb

Ageing is a complex process involving physical, psychological, and environmental factors. Scientists believe that ageing can be programmed in the womb. One example of stress during pregnancy is the administration of glucocorticoids, i. e. synthetic stress hormones to accelerate fetal lung maturation in premature labor to allow breathing after birth. Could exposure to these stress hormones have an effect on health later in life?

8 Mar 2012