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UCLA researchers reveal reversibility of Friedreich's ataxia in mouse models

In children and adults with Friedreich's ataxia, an inherited disease that causes damage to the nervous system, a loss of coordination typically progresses to muscle weakness and can involve vision, diabetes, and other problems over the course of several years.

20 Dec 2017

Use of smoking cessation drug may put people at higher risk for cardiovascular events

Varenicline, one of the most commonly prescribed drugs for helping people quit smoking, may put them at higher risk for a cardiovascular event, according to new research published online in the American Journal of Respiratory and Critical Care Medicine.

20 Dec 2017

Ludwig study elucidates mechanism behind metabolic vulnerability of some breast tumors

Scientists have known since the 1980s that many cancer cells are relatively sensitive to the deprivation of an essential amino acid known as methionine. It has, however, long been unclear what causes such marked dependency on methionine.

20 Dec 2017

Study finds new way to explain hearing loss caused by cancer drug

Scientists have found a new way to explain the hearing loss caused by cisplatin, a powerful drug used to treat many forms of cancer. Using a highly sensitive technique to measure and map cisplatin in mouse and human inner ear tissues, researchers found that forms of cisplatin build up in the inner ear.

20 Dec 2017

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

UC San Francisco physician-scientists have developed a test that can predict how patients with juvenile myelomonocytic leukemia (JMML) will respond to treatment, and may also be able to identify patients who are likely to recover spontaneously with little to no treatment.

19 Dec 2017

Study identifies potential markers for early diagnosis, treatment of oral tongue cancer

Squamous cell carcinoma of the tongue, also known as oral tongue cancer, is an aggressive form of cancer that generally affects older people. Patients with the disease often find it difficult to eat, swallow food, or speak.

19 Dec 2017

Dysfunctional gene may be cause of Crohn's disease in some patients

This holiday season, millions of people will gather at airports ready to board planes for destinations around the world. Depending on the environment at their destination, their suitcases may be filled with sunscreen and bathing suits, or heavy parkas and mittens.

19 Dec 2017

New scalp device delivering electric fields improves survival in patients with glioblastoma

A device attached to a patient's scalp that delivers a continuous dose of low-intensity electric fields improves survival and slows the growth of a deadly brain tumor, according to a new clinical trial led by a Northwestern Medicine scientist and published Dec. 19 in the journal JAMA.

19 Dec 2017

Study: People with rare diseases at high risk for experiencing poor quality of life

People with rare diseases are at high risk for experiencing poor quality of life, including increased levels of anxiety, depression, pain, fatigue and limited ability to participate in society, a new study from an Oregon State University shows.

19 Dec 2017

Study finds combination therapy as effective strategy to treat ovarian cancers

Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.

19 Dec 2017

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence, recently earned a second phase of grant funding in the amount of $10.8 million for an additional five years.

19 Dec 2017

Electric fields therapy leads to better overall, progression-free survival in glioblastoma patients

Patients with glioblastoma, an aggressive brain tumor who received a type of electric fields therapy that interferes with cell division had better overall survival and survival without progression of the tumor compared to standard chemotherapy.

19 Dec 2017

Researchers use genomics to advance understanding of Parkinson´s disease

It is widely known that genomics has already begun to influence medicine and that bioinformatics holds the key for developing new medical approaches, but how does medical genomics really work?

19 Dec 2017

Immune system plays key role in development of atherosclerosis

The immune system plays an important role in the development of atherosclerosis, the underlying cause of cardiovascular diseases. Thomas van der Heijden has discovered that immunosuppressants may play a preventative role. PhD defense 19 December.

19 Dec 2017

Zinc present in semen determines male fertility, study shows

Trace levels of zinc present in semen is a vital determinant of male fertility, a recent study in Bangladesh capital Dhaka concludes.

19 Dec 2017

Ottawa researchers use viruses to target and destroy HIV

While Ottawa researchers are known for their work on cancer-fighting viruses, one team is applying these viruses to a new target: HIV.

19 Dec 2017

TSRI scientists uncover new insights into regulatory network behind axon termination

All things must come to an end. This is particularly true for neurons, especially the extensions called axons that transmit electrochemical signals to other nerve cells. Without controlled termination of individual neuron growth, the efficient and accurate construction of a nervous system is in serious jeopardy.

19 Dec 2017

Study suggests new treatment option for most lethal form of breast cancer

The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine.

18 Dec 2017

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

By encapsulating bilirubin within tiny nanoparticles, researchers from North Carolina State University and the Ohio State University have improved the survival rates of pancreatic islet cells in vitro in a low-oxygen environment.

18 Dec 2017

EPFL scientists create gold nanoparticles to combat all viruses

HIV, dengue, papillomavirus, herpes and Ebola - these are just some of the many viruses that kill millions of people every year, mostly children in developing countries. While drugs can be used against some viruses, there is currently no broad-spectrum treatment that is effective against several at the same time, in the same way that broad-spectrum antibiotics fight a range of bacteria.

18 Dec 2017

Cell News and Research

UCLA researchers reveal reversibility of Friedreich's ataxia in mouse models

Use of smoking cessation drug may put people at higher risk for cardiovascular events

Ludwig study elucidates mechanism behind metabolic vulnerability of some breast tumors

Study finds new way to explain hearing loss caused by cancer drug

Scientists develop test to predict treatment outcomes in patients with childhood leukemia

Study identifies potential markers for early diagnosis, treatment of oral tongue cancer

Dysfunctional gene may be cause of Crohn's disease in some patients

New scalp device delivering electric fields improves survival in patients with glioblastoma

Study: People with rare diseases at high risk for experiencing poor quality of life

Study finds combination therapy as effective strategy to treat ovarian cancers

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

Electric fields therapy leads to better overall, progression-free survival in glioblastoma patients

Researchers use genomics to advance understanding of Parkinson´s disease

Immune system plays key role in development of atherosclerosis

Zinc present in semen determines male fertility, study shows

Ottawa researchers use viruses to target and destroy HIV

TSRI scientists uncover new insights into regulatory network behind axon termination

Study suggests new treatment option for most lethal form of breast cancer

Nano-encapsulation of bilirubin could enhance survival rates of pancreatic islet cells

EPFL scientists create gold nanoparticles to combat all viruses

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