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Glowing mice could mark major step forward for new gene therapy

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

16 Feb 2017

Taking prostate cancer drug with low-fat breakfast can be effective and less expensive, study finds

Taking one-fourth the standard dose of a widely used drug for prostate cancer with a low-fat breakfast can be as effective - and four times less expensive - as taking the standard dose as recommended: on an empty stomach.

14 Feb 2017

Scientists identify gene variants that predispose children to developing Kawasaki disease

Kawasaki disease (KD) is the most common acquired heart disease in children. Untreated, roughly one-quarter of children with KD develop coronary artery aneurysms -- balloon-like bulges of heart vessels -- that may ultimately result in heart attacks, congestive heart failure or sudden death.

9 Feb 2017

Precision-medicine approach could improve accuracy of PSA-based prostate cancer screening tests

A new study led by researchers at UC San Francisco and Kaiser Permanente has identified genetic predictors of normal prostate-specific antigen (PSA) levels in healthy men, which could be used to improve the accuracy of PSA-based prostate cancer screening tests.

3 Feb 2017

New PET radiotracer effectively detects early and advanced stages of prostate cancer

In the featured article from the February 2017 issue of the Journal of Nuclear Medicine, researchers document the first-in-human application of a new imaging agent to help find prostate cancer in both early and advanced stages and plan treatment.

1 Feb 2017

Valo Therapeutics develops novel oncolytic viral vaccines for treatment of multiple forms of cancer

A spin-out from the University of Helsinki, Valo Therapeutics is developing novel oncolytic viral vaccines for the treatment of multiple forms of cancer.

31 Jan 2017

ALCMI and Scancell collaborate to advance cancer vaccine clinical trials in NSCLC patients

The Addario Lung Cancer Medical Institute, the Bonnie J. Addario Lung Cancer Foundation and Scancell Holdings PLC today announce a collaboration to evaluate the use of Scancell's second innovative cancer vaccine, SCIB2, from its ImmunoBody platform to treat non-small cell lung cancer.

30 Jan 2017

New computer program helps discover 1000 new mutations in blood group genes

1000 new mutations in the blood group genes: that is what physician and former programmer Mattias Möller found in his research study in which he developed new software and investigated blood group genes in 2504 people.

28 Jan 2017

UAB researchers find how gut fails to prevent HIV-1 infection

The barrier between the gut and the bloodstream is severely damaged in the first few weeks of infection by HIV-1 virus.

28 Jan 2017

Quest Diagnostics introduces new HBV test service to help evaluate patient’s response to drug therapies

24 Jan 2017

A test to evaluate Hepatitis B therapy launched by Quest Diagnostics

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced the launch of a new test service that helps physicians evaluate a patient’s response to drug therapies used to treat infection with the hepatitis B virus (HBV). The first test of its kind available in the United States, the test is significant because it may help physicians tailor more effective treatments for the up to 2.2 million individuals infected with HBV.

23 Jan 2017

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

Using a novel approach for imaging the movement of immune cells in living animals, researchers from the Massachusetts General Hospital Center for Immunology and Inflammatory Diseases have identified what appear to be the initial steps leading to joint inflammation in a model of inflammatory arthritis.

20 Jan 2017

A quarter of men could safely avoid prostate biopsy if MRI is used

Performing an MRI scan of men with suspected prostate cancer could spare a quarter of men from having to undergo prostate biopsy, according to a study published in The Lancet.

20 Jan 2017

UCF researcher combines new and old science to create method for speedy medical tests

A UCF researcher has combined cutting-edge nanoscience with a magnetic phenomenon discovered more than 170 years ago to create a method for speedy medical tests.

20 Jan 2017

New research exposes cellular responses linked to bird flu vaccine

New research from Vanderbilt eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu.

19 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Research findings could lead to development of novel therapeutic approaches against viral infections

Life is a question of balance, and the body is no exception. Expression levels of certain proteins can affect the immune system's ability to neutralize a virus.

12 Jan 2017

Scientists develop 3-D organoid to unravel immune response during infection

What if you could design an adaptable, biomaterials-based model of an organ to track its immune response to any number of maladies, including cancer, transplant rejection and the Zika virus? The lab of Ankur Singh, assistant professor in the Sibley School of Mechanical and Aerospace Engineering, has asked - and begun to answer - that very question.

6 Jan 2017

Study shows promising results for treating lymphoma patients with immune cell therapy

Lymphoma is the most common blood cancer. The disease occurs when immune cells called lymphocytes multiply uncontrollably. Cancerous lymphocytes can travel throughout the body and form lymph node tumors.

6 Jan 2017

Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells.

6 Jan 2017

Antigen News and Research

Glowing mice could mark major step forward for new gene therapy

Taking prostate cancer drug with low-fat breakfast can be effective and less expensive, study finds

Scientists identify gene variants that predispose children to developing Kawasaki disease

Precision-medicine approach could improve accuracy of PSA-based prostate cancer screening tests

New PET radiotracer effectively detects early and advanced stages of prostate cancer

Valo Therapeutics develops novel oncolytic viral vaccines for treatment of multiple forms of cancer

ALCMI and Scancell collaborate to advance cancer vaccine clinical trials in NSCLC patients

New computer program helps discover 1000 new mutations in blood group genes

UAB researchers find how gut fails to prevent HIV-1 infection

Quest Diagnostics introduces new HBV test service to help evaluate patient’s response to drug therapies

A test to evaluate Hepatitis B therapy launched by Quest Diagnostics

Novel approach for imaging immune cell movements identifies initial steps in inflammatory arthritis

A quarter of men could safely avoid prostate biopsy if MRI is used

UCF researcher combines new and old science to create method for speedy medical tests

New research exposes cellular responses linked to bird flu vaccine

Could pathogen infection really lead to Alzheimer’s?

Research findings could lead to development of novel therapeutic approaches against viral infections

Scientists develop 3-D organoid to unravel immune response during infection

Study shows promising results for treating lymphoma patients with immune cell therapy

Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

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