Central Nervous System News and Research

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Teva acquires Cephalon

Teva Pharmaceutical Industries Ltd. announced today that it has completed its acquisition of Cephalon, Inc. The combined company will have a significant presence in over 60 countries and generated approximately $20 billion in revenues on a pro-forma basis for the twelve months ended June 2011.

15 Oct 2011

Micromet receives FDA feedback on blinatumomab registration for R/R ALL

Micromet, Inc. today outlined a clinical development plan intended to support U.S. registration of its lead product candidate blinatumomab in patients with B-precursor relapsed/refractory (r/r) acute lymphoblastic leukemia.

14 Oct 2011

GFAP protein levels can help identify HIE in newborns

Johns Hopkins researchers have discovered that increased blood levels of a protein specific to central nervous system cells that are vital to the brain's structure can help physicians identify newborns with brain injuries due to lack of oxygen.

14 Oct 2011

USPTO issues patent to Rexahn's new anti-cancer arylisoquinolinamine compounds

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that the United States Patent & Trademark Office has issued U.S. Patent No. 8,034,829 to Rexahn, entitled "5, 6, or 7-Substituted-3-(hetero) arylisoquinolinamine derivatives and therapeutic use thereof."

13 Oct 2011

Scientists discover two HIV variants in cerebrospinal fluid of HAD patients

When the virus that causes AIDS infects the central nervous system, it can lead to the development of a severe neurological disease called HIV- associated dementia.

7 Oct 2011

Teriflunomide drug reduces relapse rate of people with MS

A new oral drug has been shown in a large international clinical trial to significantly reduce the relapse rate of people with multiple sclerosis and to slow the progression of the disease.

7 Oct 2011

Measurable changes in brain function may be a consequence of early HIV infection

Measurable changes in brain function and communication between brain regions may be a consequence of virus-induced injury during the early stages of human immunodeficiency virus (HIV) infection.

7 Oct 2011

Researchers gain insight on how roundworm's brain operates as it moves

Using new optical equipment, a team of 11 researchers put roundworms into a world of virtual reality, monitored both their behavior and brain activity and gained unexpected information on how the organism's brain operates as it moves.

4 Oct 2011

Strong connection between preterm birth and risk of epilepsy

Being born prematurely may increase your risk of developing epilepsy as an adult, according to a new study published in the October 4, 2011, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Oct 2011

AMRI announces final results from ALB-127158(a) Phase I clinical studies on obesity

AMRI announced today the final results from its Phase I clinical studies on its novel MCH1 receptor antagonist, ALB-127158(a) during the 29th Annual Scientific Meeting of the Obesity Society in Orlando, Fla.

4 Oct 2011

IMRIS unveils VISIUS Surgical Theatre

IMRIS Inc. today officially launched VISIUS Surgical Theatre, its new global product branding at the Congress of Neurological Surgeons (CNS) being held in Washington DC.

3 Oct 2011

Planned clinical trial of Adeona's zinc-based therapy for ALS patients to be featured at ALS Summit

Adeona Pharmaceuticals, Inc., a developer of innovative medicines for serious central nervous system diseases, announced today that its planned clinical trial of the Company's proprietary zinc-based therapy for patients suffering from amyotrophic lateral sclerosis, also known as Lou Gehrig's Disease, will be featured during the Hot Topics session at the 2011 California ALS Research Summit on Saturday, October 1, 2011.

1 Oct 2011

UCI study shows promise of metabolic therapy for autoimmune diseases

A glucosamine-like dietary supplement suppresses the damaging autoimmune response seen in multiple sclerosis, according to a UC Irvine study.

1 Oct 2011

Takeda acquires Nycomed

Takeda Pharmaceutical Company Limited ("Takeda", TSE: 4502) announced it has completed its acquisition of Nycomed A/S for 9.6 billion Euro on a cash-free, debt-free basis and made Nycomed a wholly owned subsidiary of Takeda effective the same day. Dr. Frank Morich has been named CEO of Nycomed in addition to his current role as Executive Vice President (EVP), International Operations, Takeda Pharmaceuticals International, Inc., a wholly owned subsidiary of Takeda America Holdings, Inc.

30 Sep 2011

UCLA scientists create mouse model for autism

UCLA scientists have created a mouse model for autism that opens a window into the biological mechanisms that underlie the disease and offers a promising way to test new treatment approaches.

30 Sep 2011

Researchers reveal how motivation facilitates motor functional recovery in stroke, SCI patients

An effective recovery has been observed in stroke patients and those with spinal cord injuries who have strong vitality and motivation to rehabilitate in clinical practice. However, it was not really clear how motivation facilitates functional recovery in brain science.

29 Sep 2011

Enrollment complete in Rexahn's Archexin Phase II trial for metastatic pancreatic cancer

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company commercializing potential best in class oncology and CNS therapeutics, today announced that it has completed enrollment for its Phase II clinical trial of Archexin in metastatic pancreatic cancer.

29 Sep 2011

Afraxis to participate in NIH's Therapeutics for Rare and Neglected Disease Program

Afraxis, a San Diego-based biotechnology company developing drugs to treat rare genetic diseases through the modulation of p21-activated kinase (PAK), announced today that it has been selected to participate in the National Institutes of Health's (NIH) Therapeutics for Rare and Neglected Disease (TRND) Program.

27 Sep 2011

High consumption of caffeinated coffee appears to reduce risk of depression in women

The risk of depression appears to decrease for women with increasing consumption of caffeinated coffee, according to a report in the September 26 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

27 Sep 2011

New findings on Complex Regional Pain Syndrome

The Complex Regional Pain Syndrome (CRPS), also known as Morbus Sudeck, is characterised by "disinhibition" of various sensory and motor areas in the brain. A multidisciplinary Bochum-based research group, led by Prof. Dr. Martin Tegenthoff and Prof. Dr. Christoph Maier, has now demonstrated for the first time that with unilateral CRPS excitability increases not only in the brain area processing the sense of touch of the affected hand. In addition, the brain region representing the healthy hand is simultaneously "disinhibited".

22 Sep 2011

Central Nervous System News and Research

Teva acquires Cephalon

Micromet receives FDA feedback on blinatumomab registration for R/R ALL

GFAP protein levels can help identify HIE in newborns

USPTO issues patent to Rexahn's new anti-cancer arylisoquinolinamine compounds

Scientists discover two HIV variants in cerebrospinal fluid of HAD patients

Teriflunomide drug reduces relapse rate of people with MS

Measurable changes in brain function may be a consequence of early HIV infection

Researchers gain insight on how roundworm's brain operates as it moves

Strong connection between preterm birth and risk of epilepsy

AMRI announces final results from ALB-127158(a) Phase I clinical studies on obesity

IMRIS unveils VISIUS Surgical Theatre

Planned clinical trial of Adeona's zinc-based therapy for ALS patients to be featured at ALS Summit

UCI study shows promise of metabolic therapy for autoimmune diseases

Takeda acquires Nycomed

UCLA scientists create mouse model for autism

Researchers reveal how motivation facilitates motor functional recovery in stroke, SCI patients

Enrollment complete in Rexahn's Archexin Phase II trial for metastatic pancreatic cancer

Afraxis to participate in NIH's Therapeutics for Rare and Neglected Disease Program

High consumption of caffeinated coffee appears to reduce risk of depression in women

New findings on Complex Regional Pain Syndrome

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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