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Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

In the five decades since camptothecin was first isolated from the bark of a tree used in traditional Chinese medicine and identified as a powerful anticancer agent, several thousand chemicals with similar structures and functions have been investigated. And while two of these analog compounds, irinotecan and topotecan, have been approved in the U.S. as treatments for cancer, both are associated with significant shortcomings.

26 Nov 2015

Personal glucose meters can also measure biomarkers in patient's blood, say US scientists

Not only glucose: It is possible that people use their personal glucose meters for the quantification of other biomarkers than glucose in their blood, say American scientists from the University of Illinois.

25 Nov 2015

Finding may lead to better understanding of male genital birth defects

University of Florida Health researchers have identified genes that are disrupted by abnormal hormone signaling at crucial points during development, a finding that may lead to a better understanding of how the most common male genital birth defects arise in humans.

24 Nov 2015

Prenatal smoking exposure can potentially affect someone's health for years after birth

New Johns Hopkins Bloomberg School of Public Health-led research finds that blood taken from children up to the age of five contains molecular evidence about whether their mothers smoked during pregnancy.

23 Nov 2015

Identifying new mechanism for aspirin in cancer prevention

Aspirin has been shown to decrease the risk of colorectal cancer and possibly other cancers. However, the risk of side effects, including in some cases severe gastrointestinal bleeding, makes it necessary to better understand the mechanisms by which aspirin acts at low doses before recommending it more generally as a preventative, says Cornelia Ulrich, PhD, Senior Director of Population Sciences at Huntsman Cancer Institute in Salt Lake City.

19 Nov 2015

University of York researchers unveil 3-D structure of cancer target enzyme

A team from the University of York has published research unveiling the 3-D structure of human heparanase, a sugar-degrading enzyme which has received significant attention as a key target in anti-cancer treatments.

19 Nov 2015

International task force aims to develop new approach to cancer prevention and treatment

Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

19 Nov 2015

New Global Energy and International Sustainability Group agree to manufacture, distribute MoringaUP Protein Bars

New Global Energy, Inc., a public company focused on Aqua-Farming, Agriculture, and Health & Wellness, has signed a distribution agreement with International Sustainability Group to manufacture and distribute MoringaUP Protein Bars based on ISG's popular AlgaeUp bars.

10 Nov 2015

Meat-rich diet may increase kidney cancer risk

A new study indicates that a meat-rich diet may increase the risk of developing kidney cancer through mechanisms related to particular cooking compounds. Also, these associations may be modified by genetic susceptibility to kidney cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study illustrates how diet and genetics may interact to impact cancer risk.

10 Nov 2015

City of Hope awarded NIH grant to study potential link between environmental factors and breast cancer

The National Institutes of Health has awarded City of Hope a five-year, $4.8 million grant to study the possible role of chemicals in the environment in the development of breast cancer during the menopausal transition in women.

6 Nov 2015

Utah chemists devise new way to detect DNA damage

University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.

6 Nov 2015

UCSF scientists identify eye drop chemical that may reverse cataracts

A chemical that could potentially be used in eye drops to reverse cataracts, the leading cause of blindness, has been identified by a team of scientists from UC San Francisco (UCSF), the University of Michigan (U-M), and Washington University in St. Louis (WUSTL).

6 Nov 2015

Ingenza and Imperial researchers work together to improve nasogastric feeding tube placement

Ingenza has teamed up with clinical scientists at Imperial College London to trial an improved diagnostic assay for confirming nasogastric (NG) tube placement. Professor George Hanna, Director of the National Institute for Health Research Diagnostic Evidence Co-operative London at Imperial College Healthcare NHS Trust, which specialises in In Vitro Diagnostics, explained: “Correct placement of NG tubes is vital, as accidental insertion of the tube into the lung instead of the gut can have serious consequences.

3 Nov 2015

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Eating a diet rich in both soy protein and isoflavones can protect menopausal women from bone weakening and osteoporosis, according to the results of a preliminary study presented today at the Society for Endocrinology annual conference in Edinburgh.

2 Nov 2015

Athletes and non-athletes gather at TCS New York City Marathon

Well known for its culture, theater, and cuisine, New York is also one of the 25 healthiest cities in the United States. It's this fitness side that will be on show this weekend with the TCS New York City Marathon.

31 Oct 2015

University of Kansas professor recognized with MERIT Award

Emily Scott, professor of medicinal chemistry at the University of Kansas, has been recognized with a MERIT Award from the National Institutes of Health's National Institute of General Medical Sciences. It's a rare and important recognition -- researchers can receive them only once in a career.

30 Oct 2015

Study reports discovery of new class of DNA repair enzyme

This year's Nobel Prize in chemistry was given to three scientists who each focused on one piece of the DNA repair puzzle. Now a new study, reported online Oct. 28 in the journal Nature, reports the discovery of a new class of DNA repair enzyme.

30 Oct 2015

Scientists call for coordinated effort to drive cutting edge microbiome research

A consortium of 48 scientists from 50 institutions in the United States - including Pamela Silver, Ph.D., a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University - are calling for a Unified Microbiome Initiative that would span national cross-institutional and cross-governmental agency support.

29 Oct 2015

New screening method can detect secondhand marijuana exposure

With increased legalization of marijuana for medicinal and recreational purposes, interest is growing in the potential health effects of its secondhand smoke. A team now reports in ACS' journal Analytical Chemistry the development of a urine screening method that is sensitive enough to detect even small amounts of chemicals that result from this exposure.

29 Oct 2015

Experts call for better risk profiling for GI cancers

Cancers of the gastrointestinal (GI) tract continue to exert their toll across Europe, with many diagnosed too late for effective treatment. Bowel cancer screening programmes are now underway in most European countries, but screening for other GI cancers is patchy and not necessarily well-targeted.

28 Oct 2015

Chemicals News and Research

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

Personal glucose meters can also measure biomarkers in patient's blood, say US scientists

Finding may lead to better understanding of male genital birth defects

Prenatal smoking exposure can potentially affect someone's health for years after birth

Identifying new mechanism for aspirin in cancer prevention

University of York researchers unveil 3-D structure of cancer target enzyme

International task force aims to develop new approach to cancer prevention and treatment

New Global Energy and International Sustainability Group agree to manufacture, distribute MoringaUP Protein Bars

Meat-rich diet may increase kidney cancer risk

City of Hope awarded NIH grant to study potential link between environmental factors and breast cancer

Utah chemists devise new way to detect DNA damage

UCSF scientists identify eye drop chemical that may reverse cataracts

Ingenza and Imperial researchers work together to improve nasogastric feeding tube placement

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Athletes and non-athletes gather at TCS New York City Marathon

University of Kansas professor recognized with MERIT Award

Study reports discovery of new class of DNA repair enzyme

Scientists call for coordinated effort to drive cutting edge microbiome research

New screening method can detect secondhand marijuana exposure

Experts call for better risk profiling for GI cancers

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