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Telemedicine approach remains a viable alternative for lung cancer screening

A novel telemedicine lung cancer screening effort during the COVID-19 pandemic shows that virtual single-visit screenings are just as effective as single-visit screenings done in person at the hospital, according to a study presented at the American College of Surgeons Virtual Clinical Congress 2021.

25 Oct 2021

SARS-CoV-2 Delta variant transmitted by fully vaccinated individuals in Provincetown, Massachusetts

A new study, posted to the medRxiv* preprint server, describes the genomic epidemiology of this outbreak. It provides a deeper understanding of viral transmission from and between fully vaccinated individuals.

25 Oct 2021

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Study shows immune profile heterogeneity amongst healthy adults

Researchers opted to use single-cell RNA-seq to observe single cells in detail as they encounter a specific antigen.

22 Oct 2021

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Targeting the dentate nucleus with deep brain stimulation (DBS) was safe and feasible for promoting post-stroke rehabilitation in a first-in-human study at Cleveland Clinic.

21 Oct 2021

Discovery could lead to new treatments for axial spondyloarthritis

In a paper published today in the journal Science Translational Medicine, researchers at the Schroeder Arthritis Institute, part of University Health Network in Toronto, have made a discovery that could lead to new treatments for axial spondyloarthritis (SpA), a painful and debilitating form of arthritis which affects 1-2% of Canadians and causes inflammation in the spine, joints, eyes, gut and skin.

20 Oct 2021

Study investigates whether continued magnetic seizure therapy can prevent relapse of depression

Treatment-resistant depression or TRD is exactly what it sounds like: a form of mental illness that defies effective therapy. It is not rare, with an estimated 3 million persons in the United States suffering from TRD.

20 Oct 2021

Children show lower seroconversion rates than adults with mild COVID-19

A new study finds that following mild COVID-19, children are more likely to remain seronegative than adults, irrespective of the viral load or symptom severity.

20 Oct 2021

The effect of a SARS-CoV-2 delta variant mutation associated with higher viral loads

A new study has focused on the effect of a deletion found in the genome of the SARS-CoV-2 Delta variant that has severely reduced the amplification of ARTIC V3 amplicon 72.

20 Oct 2021

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

Researchers have been investigating the response of antibodies created against SARS-CoV-2 by the Pfizer-BioNTech six months after vaccination.

20 Oct 2021

An investigation of three SARS-CoV-2 mRNA doses in multiple sclerosis vaccine non-responders

A clinical study by a team of scientists from Norway aimed to assess the immunogenicity and safety of a third dose of COVID-19 mRNA vaccine in MS patients treated with anti-CD20 therapy or fingolimod. A preprint version of the study, which is yet to undergo peer review, is available on the medRxiv* server.

20 Oct 2021

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

A new study published in the journal Annals of Internal Medicine conducted systematic surveillance involving 2,397 HCWs who were fully vaccinated with the Pfizer-BioNTech BNT162 vaccine at the ASST Settelaghi hospitals, Italy, in February 2021.

19 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

COVID-19 protocols may remain important even for college campuses with 100% vaccine rates

Most universities are encouraging vaccination, and many have mandated vaccination for all students. Given the availability of effective vaccines, there is a growing need to reevaluate the importance of university COVID-19 protocols.

18 Oct 2021

Telehealth to the rescue for children’s mental health during COVID

A new study concludes that the lack of transportation led to impairments in child mental health services.

18 Oct 2021

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

Researchers from Singapore conducted a study to assess the spike protein-specific humoral and cellular immunity in Ad26.COV2.S vaccinated individuals either primed with Ad26.COV2.S only, or boosted with a homologous or heterologous second dose.

18 Oct 2021

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

To address the gaps in the knowledge, a team of researchers from the University of California and the Gladstone Institute of Virology conducted 39-parameter phenotyping by cytometry by time of flight (CyTOF) on 33 longitudinal specimens from 11 mRNA-vaccinated individuals, of which six had previously been infected and recovered from COVID-19.

18 Oct 2021

Researchers identify common side effects of three COVID-19 vaccines

COVID-19 vaccines remain the best tool in the pandemic toolbox against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). But they are not perfect; reports have surfaced of mild to severe side effects after vaccination. A new study from researchers in the Lampe & Company GmbH & Co. KG compared the severity of adverse events from each coronavirus vaccine.

17 Oct 2021

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

The efficacy and safety of a DNA-based vaccine are investigated, finding that the unique vaccine imparts a robust and long-lasting immunogenic response.

15 Oct 2021

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

The results of a phase 2 clinical trial featuring a SARS-CoV-2 recombinant protein vaccine developed by GlaxoSmithKline are reported, demonstrating a favorable immune response amongst both naïve and non-naïve adults with an acceptable safety profile.

15 Oct 2021

Frequency News and Research

Telemedicine approach remains a viable alternative for lung cancer screening

SARS-CoV-2 Delta variant transmitted by fully vaccinated individuals in Provincetown, Massachusetts

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Study shows immune profile heterogeneity amongst healthy adults

First-in-human study of DBS for post-stroke rehabilitation shows encouraging results

Discovery could lead to new treatments for axial spondyloarthritis

Study investigates whether continued magnetic seizure therapy can prevent relapse of depression

Children show lower seroconversion rates than adults with mild COVID-19

The effect of a SARS-CoV-2 delta variant mutation associated with higher viral loads

BNT162b2 mRNA COVID-19 vaccine-induced antibodies wane over six month period

An investigation of three SARS-CoV-2 mRNA doses in multiple sclerosis vaccine non-responders

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

COVID-19 protocols may remain important even for college campuses with 100% vaccine rates

Telehealth to the rescue for children’s mental health during COVID

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

Researchers identify common side effects of three COVID-19 vaccines

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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