Protein C News and Research

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Stanford's muscle chips reveal microgravity's impact on muscle regeneration

A gentle rumble ran under Ngan Huang's feet as a rocket carrying her research - live, human muscle cells grown on scaffolds fixed on tiny chips - lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory.

25 Jul 2024

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

TMDU researchers demonstrate proof of concept of antisense nucleic acid therapy to prevent the spread of α-synuclein pathologies in synucleinopathies.

25 Jul 2024

New insights into how genetic variants influence disease risk

A new study by scientists at deCODE Genetics, a subsidiary of Amgen, shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to various diseases and other human traits.

25 Jul 2024

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Millions of adults have atrial fibrillation - an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

Comprehensive analysis of Alzheimer’s brain tissue identifies novel biomarkers

From studying the human genome, to analyzing the way proteins are encoded, or monitoring RNA expression, researchers are rapidly gaining a far richer understanding of the complex genetic and cellular mechanisms that underpin dementia. But there's a catch: While new technologies are revealing myriad avenues for Alzheimer's research, it's impossible to know in advance which research pathways will lead to effective treatments.

25 Jul 2024

New insights into p16 protein could lead to advances in cancer diagnosis and treatment

Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis of various cancers.

25 Jul 2024

Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood.

24 Jul 2024

WashU study reveals key mechanisms of biological clocks

In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life.

24 Jul 2024

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Researchers discovered that oligodendrocytes, not just neurons, produce amyloid β in Alzheimer's disease, and suppressing their activity improves disease pathology. This finding suggests new therapeutic targets for Alzheimer's treatment.

24 Jul 2024

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Indiana University School of Medicine researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

24 Jul 2024

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Researchers in George Mason University's Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature's Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications.

24 Jul 2024

Breakthrough in acute myeloid leukemia treatment targets stem cells

Acute myeloid leukemia is one of the deadliest cancers. Leukemic stem cells responsible for the disease are highly resistant to treatment.

24 Jul 2024

Simple blood test may predict CAR-T therapy success in multiple myeloma

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

24 Jul 2024

Study unveils key mechanisms behind colorectal cancer metastasis to the liver

In cases where cancer is fatal, nine out of ten times the culprit is metastasis.

24 Jul 2024

Creating the first genetically susceptible mice for late-onset Alzheimer's

Mice don't get Alzheimer's - and while that's good news for mice, it's a big problem for biomedical researchers seeking to understand the disease and test new treatments.

24 Jul 2024

Breakthrough research identifies fibrin as key factor in preterm brain bleeds

Mark Petersen, MD, has seen firsthand the devastating effects of brain bleeds in premature babies. It's an exceedingly common condition that affects up to 20 percent of infants born before 28 weeks of gestation, bringing an increased risk for developmental delays and autism.

24 Jul 2024

Kaempferol's promise in fighting triple-negative breast cancer

Review highlights kaempferol's potential in treating triple-negative breast cancer through various anticancer mechanisms and improving chemotherapeutic efficacy.

24 Jul 2024

Lifestyle and socioeconomic status affect health impacts of ultra-processed foods

A recent study found that lifestyle and socioeconomic factors influence the negative impact of ultra-processed foods (UPF) on health-related quality of life (HRQoL). Higher UPF intake is linked to poorer physical health, especially among women, smokers, and those with low socioeconomic status.

24 Jul 2024

Proteomic signatures enhance risk prediction for both common and rare diseases

Researchers have developed sparse prediction models combining plasma proteins and clinical data to predict the 10-year risk of 218 diseases. The study, involving over 41,000 participants, highlights the enhanced predictive power of proteomic signatures.

24 Jul 2024

Unveiling nature’s hunters: Dr. Skylar Johnson's research on carnivorous pitcher plants with Absorbance 96 & One in Borneo's rainforests

In this interview, Dr. Skylar Johnson shares her thrilling adventures and groundbreaking research on carnivorous Nepenthes pitcher plants in the lush rainforests of Borneo.

From Byonoy 24 Jul 2024

Protein C News and Research

Stanford's muscle chips reveal microgravity's impact on muscle regeneration

Novel antisense therapy targets α-synuclein pathologies in neurodegenerative diseases

New insights into how genetic variants influence disease risk

Tiny titin mutation linked to developmental heart defects and adult atrial fibrillation

Comprehensive analysis of Alzheimer’s brain tissue identifies novel biomarkers

New insights into p16 protein could lead to advances in cancer diagnosis and treatment

Cryo-electron microscopy reveals how membrane microdomains respond to mechanical stress

WashU study reveals key mechanisms of biological clocks

Oligodendrocytes identified as key amyloid β producers in Alzheimer's disease

Breakthrough gene therapy restores dystrophin protein in Duchenne muscular dystrophy

Proof-of-concept animal studies demonstrate a step forward in the fight against HIV

Breakthrough in acute myeloid leukemia treatment targets stem cells

Simple blood test may predict CAR-T therapy success in multiple myeloma

Study unveils key mechanisms behind colorectal cancer metastasis to the liver

Creating the first genetically susceptible mice for late-onset Alzheimer's

Breakthrough research identifies fibrin as key factor in preterm brain bleeds

Kaempferol's promise in fighting triple-negative breast cancer

Lifestyle and socioeconomic status affect health impacts of ultra-processed foods

Proteomic signatures enhance risk prediction for both common and rare diseases

Unveiling nature’s hunters: Dr. Skylar Johnson's research on carnivorous pitcher plants with Absorbance 96 & One in Borneo's rainforests

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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