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Opiate addiction disorders associated with opioid-induced hyperalgesia

Patients with addictive disorders who take methadone or other opioid medications for pain will experience heightened sensitivity to pain, known as hyperalgesia, and new research published in The Journal of Pain shows that the condition does not improve over the course of treatment.

23 Apr 2012

OncoSec reports positive interim data from ElectroChemotherapy Phase IV head and neck cancer study

OncoSec Medical Inc., which is developing its advanced-stage OncoSec Medical System (OMS) ElectroOncology therapies to treat solid tumors, today announced positive interim analysis of data from 81 subjects in a Phase IV study of primary and locally recurrent squamous cell carcinoma of the head and neck (HNSCC) treated with OMS ElectroChemotherapy in Europe.

23 Apr 2012

First Edition: April 23, 2012

Today's headlines feature advance information about what the trustees who oversee Medicare and Social Security will say about the financial well-being of these massive programs when they release their annual report later today.

23 Apr 2012

RaySearch receives order for its RayStation treatment planning system from HUMC

RaySearch Laboratories has received an order for its RayStation treatment planning system from Hallym University Medical Center in Seoul, South Korea.

23 Apr 2012

Preliminary data hint at how neem extracts may stop replication of HIV virus

Tall, with dark-green pointy leaves, the neem tree of India is known as the "village pharmacy." As a child growing up in metropolitan New Delhi, Sonia Arora recalls on visits to rural areas seeing villagers using neem bark to clean their teeth. Arora's childhood memories have developed into a scientific fascination with natural products and their power to cure illnesses.

23 Apr 2012

HBO2 therapy can reduce neuropathic pain

Chronic pain affects about 76 million people in the U.S. and carries an economic burden of nearly $100 billion annually. The most frequently used medications, narcotic and non-narcotic analgesic drugs (e.g., morphine, ibuprofen, etc.), do not provide complete or sustained relief of chronic pain. Scientists are currently seeking alternative solutions for chronic pain management.

23 Apr 2012

Scientists grow hair on bald mice

Japanese researchers have successfully regrown hair on a bald mouse. This could mean hair related solutions for many men and women with baldness in future.

22 Apr 2012

VeriStrat test may be useful for NSCLC clinical decision-making

Results from the combined analysis of two European Phase II trials were presented today at the 3rd European Lung Cancer Conference in Geneva, Switzerland. The VeriStrat retrospective analysis was performed on serum samples from advanced non-squamous non-small cell lung cancer (NSCLC) patients treated with the combination therapy bevacizumab plus erlotinib.

21 Apr 2012

Orthopaedic research studies in the Journal of Bone and Joint Surgery

Below are highlights of orthopaedic research studies appearing in the April 18th issue of the Journal of Bone and Joint Surgery (JBJS), as well as the issue's full Table of Contents.

21 Apr 2012

UNAIDS welcomes new WHO guidelines for HIV testing, counseling, ART for couples

UNAIDS on Thursday "called on all countries to implement new WHO guidelines that encourage couples to go together for HIV testing to ascertain their status" and recommend offering antiretroviral therapy (ART) to people living with HIV who have a partner without HIV, "even when they do not require it for their own health," the U.N. News Centre reports.

21 Apr 2012

First treatment guidelines for NMDA-receptor encephalitis

A mysterious, difficult-to-diagnose, and potentially deadly disease that was only recently discovered can be controlled most effectively if treatment is started within the first month that symptoms occur, according to a new report by researchers from the Perelman School of Medicine at the University of Pennsylvania.

21 Apr 2012

EMA CHMP recommends approval of AMAG’s ferumoxytol

AMAG Pharmaceuticals, Inc. today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued a positive opinion for the approval of ferumoxytol, an intravenous (IV) iron therapy, for the treatment of iron deficiency anemia (IDA) in adult patients with chronic kidney disease.

21 Apr 2012

Scientists discover tumor-targeting neural stem cells

Could engineered human stem cells hold the key to cancer survival? Scientists at the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, have discovered that neural stem cells possess the innate ability to target tumor cells outside the central nervous system. This finding, which was demonstrated successfully on breast cancer cells, was recently published in leading peer reviewed journal, Stem Cells.

21 Apr 2012

Researchers uncover 22 new genes linked with autism, other neurodevelopmental disorders

When chromosomes replicate, sometimes there is an exchange of genetic material within a chromosome or between two or more chromosomes without a significant loss of genetic material. This exchange, known as a balanced chromosomal abnormality (BCA), can cause rearrangements in the genetic code.

21 Apr 2012

Study finds under-treatment of RHD in India, Africa

Rheumatic heart disease (RHD) is significantly under-treated in Africa and India according to the preliminary findings of a new global study presented today at the World Congress of Cardiology.

21 Apr 2012

Chemotherapy, radiation affect cognitive function of women with breast cancer

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and University of Kentucky have found that breast cancer survivors who have had chemotherapy, radiation or both do not perform as well on some cognitive tests as women who have not had cancer.

21 Apr 2012

Researchers revisit Charcot's vibration therapy for Parkinson's disease

In the 19th century, Jean-Martin Charcot, the celebrated neurologist, developed a "vibration chair," to relieve symptoms of Parkinson's disease. Charcot reported improvements in his patients, but he died shortly thereafter and a more complete evaluation of the therapy was never conducted.

20 Apr 2012

Nanoscale films promote bone growth

Every year, more than a million Americans receive an artificial hip or knee prosthesis. Such implants are designed to last many years, but in about 17 percent of patients who receive a total joint replacement, the implant eventually loosens and has to be replaced early, which can cause dangerous complications for elderly patients.

20 Apr 2012

New data provides hope for HCV non-responders

New data from a number of clinical trials presented for the first time at the International Liver Congress- 2012 provides hope for previously difficult to treat hepatitis C (HCV) patient populations.

20 Apr 2012

Study supports previously reported positive links between vitamin D and testosterone

A new study conducted by the Harvard School of Public Health, released in the Journal of Clinical Endocrinology, suggests that maintaining a high level of vitamin D supplementation increases the level of testosterone in men.

20 Apr 2012