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'Aggressive' surgery for early stage lung cancer provides better outcomes

Patients with early stage lung cancer live longer when they receive a lobectomy- the most common type of operation for the disease- rather than a less extensive operation or radiation treatment, according to a study published online today in The Annals of Thoracic Surgery.

30 Nov 2017

Study focuses on improving pharmacokinetic properties of therapeutic aptamers

Designing new therapeutic DNA aptamers with diverse side chains can improve their ability to interact with targets, and a new study describes characteristics of these side chains that may determine how long the aptamers remain in the bloodstream.

30 Nov 2017

Experts offer research strategies to yield more protective flu vaccine candidates

In a New England Journal of Medicine perspective, experts from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the World Health Organization Collaborating Centre for Reference and Research on Influenza in Melbourne discuss how the process of preparing seasonal influenza vaccines in eggs may contribute to their limited effectiveness.

30 Nov 2017

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

Regenerative medicine researchers at UT Southwestern Medical Center developed an improved and simplified gene-editing technique using CRISPR/Cas9 tools to correct a common mutation that causes Duchenne muscular dystrophy.

30 Nov 2017

NCCN creates new resource for patients who develop AIDS-related Kaposi sarcoma

The National Comprehensive Cancer Network –your best resource in the fight against cancer for more than two decades – has created a new resource for patients living with HIV who develop AIDS-related Kaposi sarcoma.

29 Nov 2017

Researchers unlock genetic processes underlying cancer

For many, breast cancer is more than just a disease – it's personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.

29 Nov 2017

Penn researchers reveal new approach to restart replication in cardiomyocytes after heart attack

In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury.

29 Nov 2017

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Most complex diseases, such as obesity, longevity, and diabetes, are largely influenced by genetic factors. But at the same time, they are also modulated by environmental stimuli, such as diet and physical activity.

29 Nov 2017

Nerve cell findings provide unique insights into neuromuscular conditions

The findings relate to a type of cell connection that allows electrical and chemical messages to flow from nerve to muscle cells, enabling motion.

29 Nov 2017

New microscope optimized to perform studies using optogenetic techniques

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication.

29 Nov 2017

Specific gene expression patterns could be key to younger looking skin

Some individuals' skin appears more youthful than their chronologic age. Although many people try to achieve this with creams, lotions, injections, and surgeries, new research published in the Journal of the American Academy of Dermatology indicates that increased expression of certain genes may be the key to intrinsically younger looking - and younger behaving - skin.

29 Nov 2017

UT Southwestern researchers take early step toward personalized care for breast cancer

UT Southwestern Medical Center researchers have developed a method to map protein changes that occur in different subtypes of breast cancer cells in response to DNA damage from a new class of chemotherapy drugs.

29 Nov 2017

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Helicobacter pylori is a bacterial pathogen that colonizes the stomach of approximately half of the world's population. Infection with H. pylori is acquired in childhood and lasts for decades.

29 Nov 2017

Powerful digital model replicates biological activity that precedes sudden cardiac death

Some heart disease patients face a higher risk of sudden cardiac death, which can happen when an arrhythmia -- an irregular heartbeat-- disrupts the normal electrical activity in the heart and causes the organ to stop pumping.

29 Nov 2017

New pluripotent stem cell technology provides insights into neuropsychiatric disorders

Studying the genetic code allows researchers to know whether some patients with neuropsychiatric disorders either have extra copies of the CHRNA7 gene or are missing copies. However, little was known about the functional consequences of this genetic imbalance in brain cells.

29 Nov 2017

USC researchers propose rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn't even require barbecue sauce.

29 Nov 2017

Study provides new insights into mechanisms contributing to ovarian cancer

Ovarian cancer is the most lethal gynecologic malignancy in the United States, resulting in an estimated 14,100 deaths and 22,500 new cases in 2017 alone. This high mortality is primarily caused by resistance to therapy and the diagnosis of ovarian cancer after it has already metastasized, which occurs in approximately 80 percent of patients.

29 Nov 2017

Cell News and Research

'Aggressive' surgery for early stage lung cancer provides better outcomes

Study focuses on improving pharmacokinetic properties of therapeutic aptamers

Experts offer research strategies to yield more protective flu vaccine candidates

UT Southwestern researchers develop improved gene-editing technique to correct DMD mutations

NCCN creates new resource for patients who develop AIDS-related Kaposi sarcoma

Researchers unlock genetic processes underlying cancer

Penn researchers reveal new approach to restart replication in cardiomyocytes after heart attack

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine

Nerve cell findings provide unique insights into neuromuscular conditions

New microscope optimized to perform studies using optogenetic techniques

Specific gene expression patterns could be key to younger looking skin

UT Southwestern researchers take early step toward personalized care for breast cancer

Scientists identify new strategies used by Helicobacter pylori to target mitochondria

Powerful digital model replicates biological activity that precedes sudden cardiac death

New pluripotent stem cell technology provides insights into neuropsychiatric disorders

USC researchers propose rules for making ribs

Study provides new insights into mechanisms contributing to ovarian cancer

Immediate ART treatment following HIV diagnosis increases retention in care, study suggests

Study provides potential explanation for increased prevalence of asthma in adult women

Mayo Clinic launches new clinical test that distinguishes IDDs from multiple sclerosis

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