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Bone cell factor can lull prostate tumor cells to sleep

Prostate tumor cells can be lulled to sleep by a factor released by bone cells, according to a study published online this week in the Journal of Experimental Medicine. Disease recurs in up to half of prostate cancer patients after treatment, often as a result of metastases that spread to distant organs.

29 Nov 2011

DFG approves establishment of new research training groups

To further enhance the promotion of early-career researchers in Germany, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) has approved the establishment of 16 new Research Training Groups. This decision was made by the DFG's relevant Grants Committee in Bonn.

29 Nov 2011

New protein involved in defense mechanism against cancer

Researchers of the Swedish medical university Karolinska Institutet and the University of Cologne, Germany, have identified a new protein involved in a defense mechanism against cancer.

28 Nov 2011

Rare syndrome's workings could help explain how brain wiring goes awry

Potential clues to how autism miswires the brain are emerging from a study of a rare, purely genetic form of the disorders that affects fewer than 20 people worldwide. Using cutting-edge "disease-in a-dish" technology, researchers funded by the National Institutes of Health have grown patients' skin cells into neurons to discover what goes wrong in the brain in Timothy Syndrome.

28 Nov 2011

Moleac launches NurAiD II in France and Belgium

Biopharmaceutical Company Moleac has announced the launch in France and Belgium of NurAiD II. NurAiD II is a natural health supplement engineered to stimulate neuroplasticity and recovery.

25 Nov 2011

Transplantation of new neurons into damaged area of the brain could restore brain functions

Without neurons reacting to the blood leptin level, the brain does not control the feeling of hunger and fullness. This type of genetic defects results in severe obesity in humans and animals.

25 Nov 2011

Even normal salt intake can cause hypertension in people suffering from sodium dysregulation

Hypertension is an endemic condition with far-reaching consequences. For instance, high blood pressure is the main cause of heart attacks and strokes. Other organs are also damaged by the chronic condition.

25 Nov 2011

Scientists decode how Machado-Joseph disease arises

Neurodegenerative diseases represent one of the greatest challenges of our aging society. However, investigation into these diseases is made particularly difficult due to the limited availability of human brain tissue. Scientists from the Life & Brain Research Center and Neurology Clinic of Bonn University have now taken a roundabout path: They reprogrammed skin cells from patients with a hereditary movement disorder into so-called induced pluripotent stem cells (iPS cells) and obtained functional nerve cells from them.

24 Nov 2011

Ribosomes spontaneously change their form during protein production

Ribosomes, the construction sites for proteins, are far more complex than previously assumed. During the production of proteins they constantly and spontaneously change their form. This performance of eukaryotic ribosomes has now been demonstrated for the first time by scientists at Charité - Universitätsmedizin Berlin, the Max-Planck-Institut für Molekulare Genetik in Berlin, and Cornell University in New York, with the aid of special electron microscopic and biophysical methods.

24 Nov 2011

Dantrolene reduces severity of walking and balance problems linked with HD

Huntington's disease (HD) is characterized by ongoing destruction of specific neurons within the brain. It affects a person's ability to walk, talk, and think - leading to involuntary movement and loss of muscle co-ordination. New research published in BioMed Central's open access journal Molecular Neurodegeneration shows that the RyanR inhibitor Dantrolene is able to reduce the severity of walking and balance problems in a mouse model of HD.

24 Nov 2011

Carefully selected young, healthy neurons can repair brain circuitry

Neuron transplants have repaired brain circuitry and substantially normalized function in mice with a brain disorder, an advance indicating that key areas of the mammalian brain are more reparable than was widely believed.

24 Nov 2011

Randox expand range of immunoturbidimetric proteins

With the recent launch of the Haptoglobin and Ceruloplasmin assays Randox now have one of the largest ranges of immunoturbidimetric proteins on the market. All reagents are liquid ready to use for added convenience; furthermore, automated applications are available for most chemistry systems eliminating the need for specialised protein analysers.

From Randox Laboratories Ltd. 24 Nov 2011

ABCC9 gene also influences duration of sleep in humans

A collaborative European study led by LMU researchers has shown that ABCC9, a known genetic factor in heart disease and diabetes, also influences the duration of sleep in humans.

24 Nov 2011

NIH-led study advances HIV vaccine research

HIV is coated in sugars that usually hide the virus from the immune system. Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus. The antibody binding site, called the V1/V2 region, represents a suitable HIV vaccine target, according to the scientists who conducted the study. In addition, their research reveals the detailed structure of the V1/V2 region, the last part of the virus surface to be visualized at the atomic level.

24 Nov 2011

Two-drug combination may alleviate radiation sickness in people

A combination of two drugs may alleviate radiation sickness in people who have been exposed to high levels of radiation, even when the therapy is given a day after the exposure occurred, according to a study led by scientists from Dana-Farber Cancer Institute and Children's Hospital Boston.

24 Nov 2011

NIH grant to support Cedars-Sinai's Department of Neurology research

The National Institutes of Health has awarded a four-year, $1.4 million grant to Cedars-Sinai's Department of Neurology to study an unexpected recent discovery: After ischemic stroke - the type caused by a clogged artery but with no bleeding into the brain - a normal protein that plays a positive role in blood clotting escapes intact arteries and damages healthy brain cells.

24 Nov 2011

Scientists identify MEGF10 defective gene responsible for muscle weakness

An international team of researchers from England and the Charité - Universitätsmedizin Berlin has presented new findings regarding the function of muscle stem cells, which are published in the current issue of the journal Nature Genetics.

23 Nov 2011

CIC microGUNE and Biodonostia test a new technique for evaluating intestinal diseases in patients

The CIC microGUNE research centre and the Biodonostia Institute have recently started testing a new technique for assessing the severity of inflammatory intestinal diseases, such as Crohn's Disease, in patients at the Donostia Hospital.

23 Nov 2011

TLRs contribute to brain damage following hypoxia in newborns

Two out of every thousand babies are at risk of brain damage in connection with birth. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have identified mechanisms behind these injuries, which could lead to better treatment and a richer life for the infants affected.

23 Nov 2011

AMP opposes NIH proposal to license cancer-related proteonomics patent

The Association for Molecular Pathology (AMP) opposed the National Institutes of Health (NIH) proposal to exclusively license the subject matter of a cancer-related proteonomics patent application filed by the Agency.

23 Nov 2011