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Merck, Endocyte enter vintafolide development and commercialization agreement

Merck, known as MSD outside the United States and Canada, and Endocyte Inc., today announced that they have entered into an agreement to develop and commercialize Endocyte's novel investigational therapeutic candidate vintafolide (EC145).

16 Apr 2012

Immunotherapy may also help elderly cancer patients

Cancer is much more likely in the elderly than the young, and their bodies often are less prepared to fight the disease and the often-toxic side effects of treatment.

16 Apr 2012

Decreasing GPA adherence among COX-2 users increases risk of upper GI complications

To relieve pain, arthritis sufferers are prescribed medications that may include non-steroidal anti-inflammatory drugs (NSAIDs) or cyclooxygenase-2 (COX-2) inhibitors, both of which can irritate the digestive tract. At times additional drugs are co-prescribed with NSAIDs or COX-2 inhibitors to prevent adverse gastrointestinal (GI) effects.

16 Apr 2012

Study calls for research into all aspects of follow-up care in lung cancer

Scientist say there is an urgent need for research into all aspects of follow-up care in lung cancer. The study presented in the May 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology focused on different follow-up strategies for patients with lung cancer.

16 Apr 2012

New drug to detect beta-amyloid plaques may help diagnose AD earlier

Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer's disease may help doctors diagnose the disease earlier, according to research that will be presented as part of the Emerging Science program (formerly known as Late-Breaking Science) at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012.

16 Apr 2012

Neurosurgeons from NYU Langone to present at AANS annual meeting

Neurosurgeons from NYU Langone Medical Center will present research and discuss surgical approaches and use of new technologies to treat neurosurgical conditions at the annual meeting of the American Association of Neurological Surgeons (AANS), held April 14-18, 2012 in Miami Beach, FL.

16 Apr 2012

SMART Heart improves cardiovascular surgical outcomes

Two years ago, 57-year-old Allus Brown underwent a simultaneous heart-kidney transplant and spent months in and out of the hospital after battling dilated cardiomyopathy, a condition that enlarges and weakens the heart. Now fully recovered, Brown is still in and out of Northwestern Memorial Hospital's Bluhm Cardiovascular Institute each week. Only nowadays when he visits, he's laughing it up, playing board games, and sharing accounts of his own struggles with heart disease as part of the Bluhm Institute's new and innovative program, SMART Heart, stress management and recreational therapy for heart patients.

16 Apr 2012

UVA engineer and biologist named recipients of Hartwell Individual Biomedical Research Awards

University of Virginia engineer Silvia Salinas Blemker and biologist Christopher Deppmann have been named recipients of 2011 Hartwell Individual Biomedical Research Awards, which provide $100,000 in annual research support for three years to each awardee.

16 Apr 2012

TJUH opens new treatment center for Barrett's esophagus

Thomas Jefferson University Hospital announces the opening of its new Jefferson Barrett's Esophagus Treatment Center, one of only a few dedicated Barrett's centers in the country and the first multidisciplinary center solely dedicated to treating Barrett's esophagus disease in Philadelphia.

16 Apr 2012

Physical activity reduces depression, enhances QOL during treatment for breast cancer

Women undergoing treatment for breast cancer might fight off distressing side effects and improve psychological well-being by staying off the couch. According to the University of Miami (UM) study, women who are physically active during treatment have less depression and an enhanced quality of life and report less debilitating fatigue.

16 Apr 2012

The key to treating AML may lie within FTL3 gene mutations

The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center.

16 Apr 2012

Viewpoints: Politics distorting views of the health system; US is more efficient than most people think

If health insurers can keep denying coverage to anyone, millions of Americans could be left to fend for themselves in a system that openly discriminates against the sick and leaves many destitute.

16 Apr 2012

Attitude may play an important role in how exercise affects menopausal women

Attitude may play an important role in how exercise affects menopausal women, according to Penn State researchers, who identified two types of women -- one experiences more hot flashes after physical activity, while the other experiences fewer.

16 Apr 2012

FDA approves HUD designation for SynCardia temporary Total Artificial Heart for destination therapy

SynCardia Systems, Inc., manufacturer of the world's first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart, announced today that the U.S. Food and Drug Administration has approved a Humanitarian Use Device (HUD) designation for the SynCardia temporary Total Artificial Heart to be used for destination therapy in addition to its current PMA approval as a bridge to transplant.

12 Apr 2012

C3BS' new production facilities in Mont-Saint-Guibert granted GMP Certification

The Belgian biotechnology company Cardio3 BioSciences (C3BS), a leader in the discovery and development of regenerative and protective therapies for the treatment of cardiac diseases, today announces that it has been granted Good Manufacturing Practice (GMP) Certification for its new production facilities in Mont-Saint-Guibert.

12 Apr 2012

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

International study that included St. Jude Children's Research Hospital reports some young acute lymphoblastic leukemia patients who fail induction therapy can achieve high cure rates without bone marrow transplantation.

12 Apr 2012

Novian Health commences multicenter Novilase Interstitial Laser Therapy clinical trial for breast cancer

Novian Health, developer of Novilase Breast Therapy, announced the company has begun a multicenter clinical trial on the use of Novilase Interstitial Laser Therapy (ILT) for the destruction of malignant breast tumors.

12 Apr 2012

Abnormally low level of SMN protein linked to movement problems in spinal muscular atrophy

An abnormally low level of a protein in certain nerve cells is linked to movement problems that characterize the deadly childhood disorder spinal muscular atrophy, new research in animals suggests.

12 Apr 2012

PPIs improve sleep and daytime quality of life for sufferers of GERD

The use of proton pump inhibitors improves the sleep and daytime quality of life for sufferers of gastroesophageal reflux disease, according to a systematic literature review in the April 2012 issue of Otolaryngology-Head and Neck Surgery.

12 Apr 2012

KineMed receives NIH RAID grant to advance FX-5A for heart disease

KineMed Inc. today announced its successful award of a Rapid Access to Intervention Development (RAID) peer-reviewed grant by the National Institute of Health to advance an HDL mimetic, designated FX-5A, designed to reverse atherosclerosis and heart disease.

12 Apr 2012

Therapy News and Research

Merck, Endocyte enter vintafolide development and commercialization agreement

Immunotherapy may also help elderly cancer patients

Decreasing GPA adherence among COX-2 users increases risk of upper GI complications

Study calls for research into all aspects of follow-up care in lung cancer

New drug to detect beta-amyloid plaques may help diagnose AD earlier

Neurosurgeons from NYU Langone to present at AANS annual meeting

SMART Heart improves cardiovascular surgical outcomes

UVA engineer and biologist named recipients of Hartwell Individual Biomedical Research Awards

TJUH opens new treatment center for Barrett's esophagus

Physical activity reduces depression, enhances QOL during treatment for breast cancer

The key to treating AML may lie within FTL3 gene mutations

Viewpoints: Politics distorting views of the health system; US is more efficient than most people think

Attitude may play an important role in how exercise affects menopausal women

FDA approves HUD designation for SynCardia temporary Total Artificial Heart for destination therapy

C3BS' new production facilities in Mont-Saint-Guibert granted GMP Certification

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

Novian Health commences multicenter Novilase Interstitial Laser Therapy clinical trial for breast cancer

Abnormally low level of SMN protein linked to movement problems in spinal muscular atrophy

PPIs improve sleep and daytime quality of life for sufferers of GERD

KineMed receives NIH RAID grant to advance FX-5A for heart disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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