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Study illustrates a powerful and efficient approach for comparing different standard treatments

A clinical trial led by researchers at The Ottawa Hospital and the University of Ottawa and published in the New England Journal of Medicine illustrates a powerful and efficient approach for comparing different standard treatments.

13 Jun 2025

Advancing precision oncology in intrahepatic cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Boosting CAR T cell survival to improve solid tumor therapy

Chimeric Antigen Receptor (CAR)-T cells are a promising cancer therapy that are made from the patient's own T cells, which are reprogrammed to fight their cancer. One of the limitations of CAR-T cell therapy is the ability of these cells to survive long enough to target the entire tumor.

13 Jun 2025

STS launches mobile app for real time surgical risk assessment

The Society of Thoracic Surgeons (STS) has launched a new mobile app that offers surgeons and multidisciplinary medical providers real-time access to its suite of adult cardiac surgery and thoracic surgery risk calculators.

13 Jun 2025

Empagliflozin preserves kidney function in heart attack patients

SGLT2 inhibitors have become a major drug used to treat diabetes, heart failure, and chronic kidney disease.

13 Jun 2025

UK study finds small proportion of early Alzheimer’s patients suitable for latest treatments

Few people in the UK with early stage Alzheimer's disease are likely to be suitable for the latest drugs which aim to halt progress of the condition, yet many are nevertheless likely to be referred for these treatments, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

13 Jun 2025

Prenatal exposure to forever chemicals linked to higher teen blood pressure

Children exposed before birth to synthetic compounds called "forever chemicals" had higher blood pressure during their teenage years, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

13 Jun 2025

Low-dose vitamin D supplements can increase effectiveness of chemotherapy in breast cancer patients

A study conducted at the Botucatu School of Medicine at São Paulo State University (FMB-UNESP) in Brazil has shown that low-dose vitamin D supplementation can increase the effectiveness of chemotherapy treatment in women with breast cancer.

13 Jun 2025

AI and film animation tools lead to breakthrough in coronavirus drug discovery

About 30% of all respiratory tract infections are caused by coronaviruses, leading to widespread illnesses and, in some cases, to epidemic and even pandemic outbreaks, as we experienced with the COVID-19 pandemic.

13 Jun 2025

Gene therapy shows long-term success in hemophilia B patients

A gene transfer approach to treating the bleeding disorder hemophilia B remains safe and effective long-term, as scientists from St. Jude Children's Research Hospital and University College London today report thirteen years of follow-up data.

12 Jun 2025

New nanopore sequencing assay advances fragile X syndrome carrier screening

Researchers have developed an innovative new nanopore sequencing assay to identify carriers of fragile X syndrome (FXS), the leading cause of monogenic autism spectrum disorder and inherited intellectual disabilities.

12 Jun 2025

‘One big beautiful bill’ would batter rural hospital finances, researchers say

Cuts to Medicaid and other federal health programs proposed in President Donald Trump's budget plan would rapidly push more than 300 financially struggling rural hospitals toward a fiscal cliff, according to researchers who track the facilities' finances.

12 Jun 2025

Lab-grown mini intestines reveal how Shigella infects human gut

Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut.

12 Jun 2025

Telehealth does not increase risk of substance use disorder in ADHD patients

Telehealth can make health care easier to access for patients with attention-deficit/hyperactivity disorder (ADHD) who need treatment, but experts worry about an increased risk of substance use disorder for patients being prescribed controlled medications such as stimulants for ADHD during these appointments.

12 Jun 2025

Peripheral arterial disease leads to more leg amputations in deprived communities

Leg amputation rates caused by arterial disease are four times as high in the most disadvantaged areas in England.

12 Jun 2025

Exercise targets specific brain cells to protect against Alzheimer’s

Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer's disease, researchers from Mass General Brigham and collaborators at SUNY Upstate Medical University have identified specific brain cell types that responded most to exercise.

12 Jun 2025

VR training tool helps clinicians improve infection control practices

Infection control researchers at Mass General Brigham have developed a virtual reality (VR) tool to train clinicians on core concepts in infection control, including cleaning and disinfecting portable medical equipment, to prevent the spread of infections throughout healthcare facilities.

12 Jun 2025