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EC grants marketing authorization for ONPATTRO (patisiran) in Europe

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the European Commission (EC) has granted marketing authorization for ONPATTRO (patisiran) for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

30 Aug 2018

Modified T lymphocytes prevent nerve cell damage in encephalitis

Scientists have found a way to prevent neuron death in Rasmussen’s encephalitis, by exploiting T lymphocytes in the immune system.

30 Aug 2018

SMA treatment may be effective even if started in children seven months and older

A drug shown to be effective in the treatment of babies with the rare muscle-wasting disease spinal muscular atrophy may be effective for muscle control even when treatment is started in children seven months and older, according to a study published in the August 29, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology. Previous studies focused on children younger than seven months old.

30 Aug 2018

Three-pronged therapy triggers axons to regrow after spinal cord injury in rodents

Neuroscientists at UCLA, Harvard University and the Swiss Federal Institute of Technology have identified a three-pronged treatment that triggers axons – the tiny fibers that link our nerve cells and enable them to communicate – to regrow after complete spinal cord injury in rodents. Not only did the axons grow through scars, they could also transmit signals across the damaged tissue.

29 Aug 2018

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Researchers at the University of Florida have discovered that a modified version of an important immune cell protein could be used to treat Alzheimer's disease.

29 Aug 2018

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Hesperos, Inc., announced today the receipt of a NIH Phase I Small Business Innovation Research grant from the National Institutes of Health National Institute on Aging to help create a new multi-organ "human-on-a-chip" model that can realistically mimic the biology of Alzheimer's Disease and the effects of potential new therapies under realistic human physiological conditions.

29 Aug 2018

Scientists regenerate nerve fibers after spinal cord injury

Scientists have discovered the biological mechanisms needed for nerve fibers to regenerate in spinal cord injury.

29 Aug 2018

Scientists discover potential treatment for Alzheimer’s disease

Scientists discovered a modified version of an immune cell receptor called a toll-like receptor that could be used as a treatment for Alzheimer’s disease.

29 Aug 2018

Ketamine's acute antidepressant effect requires opioid system activation, finds study

A new study appearing online today from the American Journal of Psychiatry finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any antidepressant's mechanism of action.

29 Aug 2018

Scientists reveal novel brain network linked to pain in Parkinsonism

Scientists have revealed a novel brain network that links pain in Parkinson's disease (PD) to a specific region of the brain, according to a report in the journal eLife.

28 Aug 2018

Researchers study motor, cognitive effects of DBS in patients with Parkinson's disease

Researchers from Charité - Universitätsmedizin Berlin have studied motor and cognitive effects of deep brain stimulation in patients with Parkinson's disease.

28 Aug 2018

New treatment can offer relief to people with chronic runny nose, postnasal drip and cough

A new treatment that delivers a freezing or near-freezing temperature to the back of the nose of patients can offer relief to people suffering from chronic stuffy or runny nose, postnasal drip and cough. These symptoms result from persistently inflamed nose and sinuses, a condition known as chronic rhinitis.

28 Aug 2018

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart - a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.

27 Aug 2018

New improved method to judge effectiveness of experimental therapies for neurodegeneration

Researchers at UBC's Okanagan campus have developed a new and improved method to judge the effectiveness of experimental therapies for neurodegeneration--the progressive loss of neurons.

27 Aug 2018

Researchers identify series of molecules involved in regeneration of damaged nerves

Researchers at Nagoya University have identified the series of molecules involved in the regeneration of damaged nerves in roundworm, showing that it largely overlaps with the signals used by the intrinsic removal system to take up and process dying cells.

24 Aug 2018

Proteins that protect neurons from destruction can be delivered through nose

Protective proteins that mitigate the destruction of nerve cells after a stroke can be administered into the brain through the nose, as Heidelberg University researchers demonstrated using a mouse model.

24 Aug 2018

Study findings shed light on fundamental feature of nerve repair

Through a study of roundworm nerve cells with severed axons, researchers at Nagoya University showed that a signaling cascade that normally functions in promoting the phagocytosis of apoptotic cells also acts in inducing axon regeneration.

24 Aug 2018

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

To successfully infect its host, the rabies virus must move from the nerve ending to the nerve cell body where it can replicate.

24 Aug 2018

Hand-held ophthalmology probe can image photoreceptors in the eyes of infants

Duke University researchers have developed a handheld probe that can image individual photoreceptors in the eyes of infants.

24 Aug 2018

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

The Muscular Dystrophy Association today announced the award of 34 new grants totaling more than $9.9 million for its summer round of funding. These new grants represent a continued commitment by MDA to fund groundbreaking research that will accelerate treatments and cures for the more than 40 diseases in its program.

24 Aug 2018

Nerve News and Research

EC grants marketing authorization for ONPATTRO (patisiran) in Europe

Modified T lymphocytes prevent nerve cell damage in encephalitis

SMA treatment may be effective even if started in children seven months and older

Three-pronged therapy triggers axons to regrow after spinal cord injury in rodents

Soluble versions of immune cell protein could help treat Alzheimer's disease, study reveals

Hesperos receives SBIR grant to create ‘human-on-a-chip’ model to mimic Alzheimer's disease

Scientists regenerate nerve fibers after spinal cord injury

Scientists discover potential treatment for Alzheimer’s disease

Ketamine's acute antidepressant effect requires opioid system activation, finds study

Scientists reveal novel brain network linked to pain in Parkinsonism

Researchers study motor, cognitive effects of DBS in patients with Parkinson's disease

New treatment can offer relief to people with chronic runny nose, postnasal drip and cough

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

New improved method to judge effectiveness of experimental therapies for neurodegeneration

Researchers identify series of molecules involved in regeneration of damaged nerves

Proteins that protect neurons from destruction can be delivered through nose

Study findings shed light on fundamental feature of nerve repair

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

Hand-held ophthalmology probe can image photoreceptors in the eyes of infants

MDA announces 34 new grants totaling $9.9 million to accelerate neuromuscular research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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