Therapy News and Research

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High-dose glucocorticoids double risk of bacterial infections in children with JIA

Children with juvenile idiopathic arthritis have higher rates of bacterial infection requiring hospitalization, and use of high-dose steroids significantly increases that risk, according to research from the University of Alabama at Birmingham.

2 May 2012

High-dose steroids increase infection risk in children with juvenile idiopathic arthritis

Children with juvenile idiopathic arthritis (JIA) have higher rates of hospitalized bacterial infection than children without JIA according to an observational study appearing in Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

2 May 2012

Interferon linked with increased risk of depression in HCV patients

There's a high rate of depression among patients with hepatitis C, but a standard treatment for the disease includes a drug, interferon, that can cause depression.

2 May 2012

Gilead commences GS-1101 Phase 3 trial in CLL

Gilead Sciences, Inc. today announced that the first patient has been dosed in a Phase 3 clinical trial evaluating the efficacy and safety of GS-1101.

2 May 2012

FDA clears Great Basin’s first C. diff molecular diagnostic test

Great Basin Corporation, a privately-held life sciences company developing sample-to-result molecular diagnostic solutions, today announced that the U.S. Food and Drug Administration (FDA) has granted approval for its first molecular diagnostic test for Clostridium difficile.

2 May 2012

Pfizer receives FDA approval for Elelyso to treat Type 1 Gaucher disease

The U.S. Food and Drug Administration today approved Elelyso (taliglucerase alfa) for long-term enzyme replacement therapy to treat a form of Gaucher disease, a rare genetic disorder.

2 May 2012

Overweight and obese teenagers with diabetes may be difficult to treat: Study

According to a major study released Sunday, several ways to manage blood sugar in teens newly diagnosed with diabetes were tested. The researchers found that nearly half of them failed within a few years and 1 in 5 suffered serious complications. This is concerning since there is an epidemic rise of Type 2 diabetes brought on by obesity.

30 Apr 2012

Removing ruptured appendix sooner lowers hospital costs, charges

Removing a child's ruptured appendix sooner rather than later significantly lowers hospital costs and charges, according to a recently published study.

30 Apr 2012

AlderMed enters distribution agreement with Gulmay Medical for Xstrahl-100 therapy system

AlderMed announced today it has entered into a three-year exclusive distribution agreement with Gulmay Medical, manufacturer of the Xstrahl-100 therapy system.

From Xstrahl 30 Apr 2012

Kadimastem, Merck Serono enter agreement for MS drug-screening platform

Kadimastem, an Israeli Biotechnology company that develops human pluripotent stem cell-related products, today announced the signing of a five year framework agreement with Merck Serono, a division of Merck KGaA, Darmstadt, Germany.

30 Apr 2012

JCO publishes Syndax erlotinib-entinostat Phase 2 study for advanced non-small cell lung cancer

Syndax Pharmaceuticals, Inc., a late-stage oncology company focused on the clinical development of epigenetic therapies in solid tumors, announced that previously reported results from ENCORE 401, a randomized, placebo controlled Phase 2 study of erlotinib with or without entinostat in advanced non-small cell lung cancer patients were published in the Journal of Clinical Oncology (JCO).

30 Apr 2012

Conjoined twins bounce back after separation surgery

Angelica Sabuco runs to kiss her sister Angelina on the cheek, and then runs away giggling. Angelina squeals and starts chasing her twin around the grass, determined to get her kiss in, too. It's hard to believe that a short while ago, these same two girls were struggling to even walk, and facing an uncertain future.

30 Apr 2012

BTG launches Voraxaze for treatment of toxic plasma methotrexate

BTG International Inc., the specialist healthcare company today announces the launch of Voraxaze (glucarpidase) in the US. Voraxaze is indicated for the treatment of toxic plasma methotrexate concentrations (>1 micromole per liter) in patients with delayed methotrexate clearance due to impaired renal function.

30 Apr 2012

MR enterography accurate in diagnosing fibrosis in pediatric patients with Crohn disease

MR enterography is superior to CT enterography in diagnosing fibrosis in pediatric patients with Crohn disease and equally as good as CT enterography in detecting active inflammation, and a new study shows.

30 Apr 2012

MCC researchers aim to improve cancer patient's quality of life and care

Researchers at Moffitt Cancer Center have placed new emphasis on gathering data on cancer patient quality of life during both treatment and survivorship. Their focus is on gathering and using that data to develop interventions to improve the quality of life for patients in treatment and for cancer survivors.

30 Apr 2012

Infusion Nurses Society to release journal iPad app

Keeping up with the latest research and commentary in infusion nursing just got easier, with the premiere of the new Journal of Infusion Nursing iPad app. The official journal of the Infusion Nurses Society (INS) will showcase the app during the INS 2012 Annual Conference in Las Vegas, April 28- May 3rd. The Journal of Infusion Nursing is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

30 Apr 2012

Detrimental effect of tetracycline on male reproductive function, sperm viability of pseudoscorpions

In a paper published today in Nature's open access journal Scientific Reports, researchers at the University of Nevada, Reno report that male pseudoscorpions treated with the antibiotic tetracycline suffer significantly reduced sperm viability and pass this toxic effect on to their untreated sons. They suggest that a similar effect could occur in humans and other species.

30 Apr 2012

Study reveals direct correlation between negative thinking about pain and poor sleep

Chronic pain sufferers who learn to dwell less on their ailments may sleep better and experience less day-to-day pain, according to results of research conducted on 214 people with chronic face and jaw pain.

27 Apr 2012

IRIDEX launches non-invasive MicroPulse Laser Trabeculoplasty for glaucoma

IRIDEX Corporation today announced the launch of a new non-invasive, in-office glaucoma procedure based on its proprietary MicroPulse technology. The new glaucoma therapy, a tissue-sparing, repeatable therapy called MicroPulse Laser Trabeculoplasty (MLT), was introduced by IRIDEX at the recent American Society of Cataract and Refractive Surgery (ASCRS).

27 Apr 2012

Blog continues coverage of International Treatment as Prevention conference in Vancouver

The Center for Global Health Policy's "Science Speaks" blog continued its coverage of the 2nd International Treatment as Prevention Workshop in Vancouver.

27 Apr 2012

Therapy News and Research

High-dose glucocorticoids double risk of bacterial infections in children with JIA

High-dose steroids increase infection risk in children with juvenile idiopathic arthritis

Interferon linked with increased risk of depression in HCV patients

Gilead commences GS-1101 Phase 3 trial in CLL

FDA clears Great Basin’s first C. diff molecular diagnostic test

Pfizer receives FDA approval for Elelyso to treat Type 1 Gaucher disease

Overweight and obese teenagers with diabetes may be difficult to treat: Study

Removing ruptured appendix sooner lowers hospital costs, charges

AlderMed enters distribution agreement with Gulmay Medical for Xstrahl-100 therapy system

Kadimastem, Merck Serono enter agreement for MS drug-screening platform

JCO publishes Syndax erlotinib-entinostat Phase 2 study for advanced non-small cell lung cancer

Conjoined twins bounce back after separation surgery

BTG launches Voraxaze for treatment of toxic plasma methotrexate

MR enterography accurate in diagnosing fibrosis in pediatric patients with Crohn disease

MCC researchers aim to improve cancer patient's quality of life and care

Infusion Nurses Society to release journal iPad app

Detrimental effect of tetracycline on male reproductive function, sperm viability of pseudoscorpions

Study reveals direct correlation between negative thinking about pain and poor sleep

IRIDEX launches non-invasive MicroPulse Laser Trabeculoplasty for glaucoma

Blog continues coverage of International Treatment as Prevention conference in Vancouver

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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