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Research reveals role of IGFBP3 in human lung development

Researchers of the University of Barcelona and the August Pi y Sunyer Biomedical Research Institute (IDIBAPS) have shown that the IGFBP3 protein plays a relevant role in human lung development.

1 Nov 2024

Radioprotective effects of Licochalcone B against radiation-induced cell damage

Radiation injury poses a serious threat to human health, causing complex and multifaceted damage to cells and tissues. Such injury can be caused by various factors, including nuclear accidents, medical radiation therapy, and space travel.

29 Oct 2024

Study aims to construct a circRNA-miRNA-mRNA network in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most fatal malignancies. Epigenetic mechanisms have revealed that noncoding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), are involved in HCC progression.

27 Oct 2024

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité – Universitätsmedizin Berlin have elucidated the role of the p53 gene in ulcerative colitis.

26 Oct 2024

RNA modifications and their role in cancer development

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications.

25 Oct 2024

Research uncovers new insights into neuronal aging and rejuvenation

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal aging — inevitable with the passing of time — is particularly accelerated and becomes a risk factor in neurodegenerative pathologies such as Alzheimer's disease.

24 Oct 2024

Scientists reveal how miRNAs shape cancer and offer new paths for treatment

Review explores how microRNAs (miRNAs) interact in cancer development, their potential in diagnosis, and innovative therapeutic strategies, including overcoming chemotherapy resistance.

20 Oct 2024

Breakthrough in understanding microtubule formation in cells

Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to another.

15 Oct 2024

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Researchers identify distinct gut microbiome metabolites in women with endometriosis, offering potential for non-invasive diagnosis and new therapies.

14 Oct 2024

Cell stress from crowding leads to slower growth and circular patterns

Like so many organisms on the planet, when cells experience mosh-pit-level crowding, they may just become stressed. Yet unlike most other life forms, cells subject to physical stress from crowding by neighbors can find some relief by dramatically slowing their own growth - and in doing so form an eye-catching pattern of concentric circles as a spectacular consequence.

12 Oct 2024

New surgical stitches capable of generating electrical charge may accelerate wound healing

Researchers developed the BioES-suture, a bioabsorbable suture that accelerates wound healing through electrical stimulation, showing superior healing outcomes.

10 Oct 2024

New insights into how DAPK3 regulates the migration of triple-negative breast cancer cells

Triple-negative breast cancer (TNBC) is the subtype of breast cancer that is the hardest to treat. TNBC patients account for more than 20,000 cases of this condition annually in the U.S. alone.

8 Oct 2024

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Inflammatory proteins linked to higher risk of endometrial cancer

Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

1 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Traditional Chinese medicine shows potential in cancer treatment

Cancer, a pervasive global health concern, remains a leading cause of mortality worldwide. Current cancer treatment modalities encompass surgery, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, all of which have significantly contributed to improving patient survival.

1 Oct 2024

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Announcing a new publication for Acta Materia Medica journal. Chemoresistance to gemcitabine (Gem) remains a substantial obstacle in the treatment of pancreatic ductal adenocarcinoma carcinoma (PDAC).

29 Sep 2024

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential to tumor progression, may be effective in treating breast cancer.

27 Sep 2024

Why children with Down’s syndrome are predisposed to developing leukaemia

The study uncovers mechanisms linking Down syndrome to leukemia, emphasizing the role of oxidative stress and genetic alterations in fetal blood development.

26 Sep 2024

Breakthrough research offers hope for improved treatment of chronic wounds

Novel research, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, has identified key molecular targets that could significantly enhance the healing of both acute and chronic wounds.

25 Sep 2024

Cell Proliferation News and Research

Research reveals role of IGFBP3 in human lung development

Radioprotective effects of Licochalcone B against radiation-induced cell damage

Study aims to construct a circRNA-miRNA-mRNA network in hepatocellular carcinoma

Study sheds new light on p53 tumor suppressor gene's role in ulcerative colitis

RNA modifications and their role in cancer development

Research uncovers new insights into neuronal aging and rejuvenation

Scientists reveal how miRNAs shape cancer and offer new paths for treatment

Breakthrough in understanding microtubule formation in cells

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Cell stress from crowding leads to slower growth and circular patterns

New surgical stitches capable of generating electrical charge may accelerate wound healing

New insights into how DAPK3 regulates the migration of triple-negative breast cancer cells

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Inflammatory proteins linked to higher risk of endometrial cancer

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

Traditional Chinese medicine shows potential in cancer treatment

Brusatol may serve as potential adjuvant therapy for pancreatic ductal adenocarcinoma

Novel approach combines glutaminase and HuR blockade to suppress breast cancer growth

Why children with Down’s syndrome are predisposed to developing leukaemia

Breakthrough research offers hope for improved treatment of chronic wounds

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