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Long-sought protein structure may help reveal how 'gene switch' works

The bacterium behind one of mankind's deadliest scourges, tuberculosis, is helping researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and the Department of Energy's Brookhaven National Laboratory (BNL) move closer to answering the decades-old question of what controls the switching on and off of genes that carry out all of life's functions.

8 Feb 2009

Multifidus muscle design contributes to spine stability

The novel design of a deep muscle along the spinal column called the multifidus muscle may in fact be key to spinal support and a healthy back, according to researchers at the University of California, San Diego School of Medicine.

7 Jan 2009

Scientists gain new insights into regulation of calpains

Scientists at St. Jude Children's Research Hospital have gained new insights into regulation of one of the body's enzyme workhorses called calpains.

19 Nov 2008

Enzyme discovery may lead to better heart and stroke treatments

A Queen's University study sheds new light on the way one of our cell enzymes, implicated in causing tissue damage after heart attacks and strokes, is normally kept under control.

19 Nov 2008

Research provides new insights into how cells accessorize their proteins

St. Jude Children's Research Hospital investigators have gained new insight into how the cell's vast array of proteins would instantly be reduced to a confusion of lethally malfunctioning molecules without a system for proteins to "accessorize" in order to regulate their function.

21 Sep 2008

Scientists find structure of critical Ebola virus protein

Scientists at the Scripps Research Institute have uncovered the structure of a critical protein from the Ebola Virus that allows viral entry in human cells.

23 Jul 2008

New super-resolution X-ray microscope

A novel super-resolution X-ray microscope developed by a team of researchers from the Paul Scherrer Institut (PSI) and EPFL in Switzerland combines the high penetration power of x-rays with high spatial resolution, making it possible for the first time to shed light on the detailed interior composition of semiconductor devices and cellular structures.

17 Jul 2008

Electrostatic-based RNA assays technique could revolutionize medical diagnostics

The dream of personalized medicine - in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profile - may be on the verge of being expanded beyond the wealthiest of nations with state-of-the-art clinics.

30 Jun 2008

New invaluable tool in drug manufacture

Drug companies could save millions thanks to a new technology to monitor crystals as they form.

8 Jun 2008

Researchers map iron transport protein - may help people suffering from blood iron disorders

Montana State University scientists in the Department of Chemistry and Bio-chemistry published new research this week that could one day affect the lives of millions around the world who suffer from blood iron disorders.

21 May 2008

Simple, painless hair test detects breast cancer

A test developed by Australian scientists which promises to be able to pick up breast cancer from a hair sample, could be commercially available later this year.

13 May 2008

Researchers mimic bacteria to synthesize magnetic nanoparticles for drug targeting and delivery

When it comes to designing something, it's hard to find a better source of inspiration than Mother Nature.

15 Apr 2008

Astrotechnology brings nanoparticle probes into sharper focus

While pondering the challenges of distinguishing one nanosize probe image from another in a mass of hundreds or thousands of nanoprobes, two investigators at Emory University and the Georgia Institute of Technology made an interesting observation. The tiny, clustered dots of light looked a lot like a starry sky on a clear night.

27 Mar 2008

First 3-D view of anti-cancer agent

Researchers from the Indiana University School of Medicine and the Purdue School of Science at Indiana University-Purdue University Indianapolis have created the first three-dimensional image of how a well-established chemotherapy agent targets and binds to DNA.

19 Mar 2008

New understanding of structure and behavior of collagen

The structure and behavior of one of the most common proteins in our bodies has been resolved at a level of detail never before seen, thanks to new research performed at the Advanced Photon Source (APS) at the U.S. Department of Energy's (DOE) Argonne National Laboratory.

27 Feb 2008

Scientists solve structure of gene regulator that plays key role in cancer

Scientists at The Wistar Institute have collaborated on a major advance in understanding a gene regulator that contributes to some of the deadliest cancers in humans.

14 Feb 2008

Structure of important neurotransmitter regulator solved

Researchers from Virginia Tech and the Brookhaven National Laboratory have solved the structure of an enzyme that is critical in the regulation of the neurotransmitter system in the human brain.

4 Feb 2008

New prototype colour 3D X-ray system

Scientists at The University of Manchester have developed a new x-ray technique that could be used to detect hidden explosives, drugs and human cancers more effectively.

From The University of Manchester 3 Dec 2007

Researchers outline structure of largest nonvirus particle ever crystallized

Researchers at UCLA's California NanoSystems Institute, the David Geffen School of Medicine at UCLA and the Howard Hughes Medical Institute have modeled the structure of the largest cellular particle ever crystallized, suggesting ways to engineer the particles for drug delivery.

27 Nov 2007

Tiny DNA molecules show liquid crystal phases, pointing to new scenario for first life on earth

A team led by the University of Colorado at Boulder and the University of Milan has discovered some unexpected forms of liquid crystals of ultrashort DNA molecules immersed in water, providing a new scenario for a key step in the emergence of life on Earth.

22 Nov 2007