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Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Anosmia, the loss of smell, is a frequent and often long-term symptom associated with COVID-19 that can severely burden a person's quality of life, making it extremely difficult to taste foods, detect airborne hazards in the environment and carry out other functions dependent on the sense.

11 Apr 2022

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Researchers used cryogenic electron microscopy (cryo-EM) to determine the structure of the spike (S) protein of BA.2 sub-variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and compared them with previously determined S structures of Omicron's BA.1 sub-variant.

11 Apr 2022

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

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11 Apr 2022

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

What happens below the cellular level when the heart contracts and relaxes has long been unexplored. Thanks to new ultra-high-resolution electron microscopy techniques, scientists can now watch the heart beating – almost at a molecular level.

8 Apr 2022

Researchers reveal why people with allergic asthma are protected from severe COVID

The vast majority of people infected with the omicron variant of SARS-CoV-2 experience mild cold-like symptoms, moderate flu-like symptoms, or no symptoms at all, but the virus is so transmissible that it still spread deep into lung tissue to cause severe disease and death in thousands of people in the United States in 2022 alone.

7 Apr 2022

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.

6 Apr 2022

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Imaging at near-atomic resolution of a key immune protein commonly known as STING has revealed a previously unrecognized binding site that appears to be pivotal for launching immune attacks, UT Southwestern scientists report in a new study.

6 Apr 2022

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

A new preprint study depicted the generation of self-assembling coronavirus disease 2019 (COVID-19) nanoparticle vaccines.

6 Apr 2022

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

A new study discovered immunoglobulins with powerful broad-acting neutralizing capacity against SARS-CoV-2 from SARS-CoV-2 convalescents.

5 Apr 2022

Dr. Annette Rinck appointed as President of Leica Microsystems

Leica Microsystems, a leading manufacturer of microscopes and scientific instruments, has announced the appointment of Dr. Annette Rinck as its President, with effect from 1 April 2022.

From Leica Microsystems GmbH 1 Apr 2022

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

An exciting study recently published in the PNAS underscores the role of a well-established cytokine IL-13 in protecting our cells against SARS-CoV-2.

31 Mar 2022

Investigating SARS-CoV-2 detection using Raman microscopy

Researchers investigated the specific intracellular signature of SARS-CoV-2 infection using Raman microscopy.

29 Mar 2022

Study explores macrophage susceptibility to SARS-CoV-2 virions

A new study investigated the susceptibility of macrophages to SARS-CoV-2 virions.

25 Mar 2022

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Researchers evaluated the stability and expression of mutations in the spike protein of SARS-CoV-2.

24 Mar 2022

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Researchers determine the differential dynamic behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins.

22 Mar 2022

Scientists reveal how 911 DNA checkpoint clamp helps repair the damaged DNA

When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem -; a failsafe that is critical to maintaining health and staving off disease.

22 Mar 2022

Researchers offer a clear picture of how the 9-1-1 clamp is recruited to sites of DNA damage

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.

21 Mar 2022

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

A new study reported the development of colorimetric sensors for the detection of SARS-CoV-2 ribonucleic acid-dependent RNA polymerase, envelope, and spike genes.

21 Mar 2022

Two clever human antibodies can target Ebola and Sudan virus

Researchers at La Jolla Institute for Immunology (LJI) are designing better therapies for treating Ebola virus and its deadly relatives.

17 Mar 2022

Electron Microscopy News and Research

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

Inflammation weakens odor signals and may be responsible for COVID19 loss of smell

Cryo-electron microscopy shows how Omicron BA.2 structure differs from BA.1 substantially

Evidence of an increased risk of neurodegeneration after SARS-CoV-2 infection

Advanced microscopy reveals exciting insights into dynamic ultrastructure of the heart

Researchers reveal why people with allergic asthma are protected from severe COVID

Researchers demonstrate how a narrow-spectrum antibiotic selectively targets C. diff

Cryo-EM imaging of a key immune protein reveals previously unrecognized binding site

Self-assembling SARS-CoV-2 spike protein-directed nanoparticle vaccines

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

Dr. Annette Rinck appointed as President of Leica Microsystems

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

Investigating SARS-CoV-2 detection using Raman microscopy

Study explores macrophage susceptibility to SARS-CoV-2 virions

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Scientists reveal how 911 DNA checkpoint clamp helps repair the damaged DNA

Researchers offer a clear picture of how the 9-1-1 clamp is recruited to sites of DNA damage

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

Two clever human antibodies can target Ebola and Sudan virus

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