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FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

The U.S. Food and Drug Administration (FDA) has issued a press release making the first even gene therapy available for treatment of children with a form of acute lymphoblastic leukemia (ALL).

30 Aug 2017

MIT engineers devise automated approach to monitor neurons

Recording electrical signals from inside a neuron in the living brain can reveal a great deal of information about that neuron's function and how it coordinates with other cells in the brain.

30 Aug 2017

Tips for packing nutritious, delicious, and affordable lunch

Lunch - a favorite subject for school kids and often a pleasant where-should-we-go dilemma for adults. Whether you're a parent filling your child's lunchbox, or a university student on a budget, UNLV instructor and registered dietitian nutritionist Samantha Coogan has tips for keeping that midday meal nutritious, delicious, and affordable.

30 Aug 2017

FDA approves first cell-based gene therapy for use in the United States

The U.S. Food and Drug Administration issued a historic action today making the first gene therapy available in the United States, ushering in a new approach to the treatment of cancer and other serious and life-threatening diseases.

30 Aug 2017

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists have discovered a network of genes and genetic regulatory elements in the lining of the intestines that has stayed remarkably the same from fishes to humans. Many of these genes are linked to human illnesses, such as inflammatory bowel diseases, diabetes and obesity.

30 Aug 2017

Stabilizing TREM2 could be viable therapeutic strategy to combat Alzheimer's disease

A gene called triggering receptor expressed on myeloid cells 2, or TREM2, has been associated with numerous neurodegenerative diseases, such as Alzheimer's disease, Frontotemporal lobar degeneration, Parkinson's disease, and Nasu-Hakola disease. Recently, a rare mutation in the gene has been shown to increase the risk for developing Alzheimer's disease.

30 Aug 2017

Researchers demystify interdomain communication pathway in Hsp70 protein

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of interdomain communication in a family of proteins known as Hsp70s - a top target of dozens of research laboratories trying to develop new anti-cancer drugs, antibiotics and treatments for Alzheimer's and Parkinson's diseases.

30 Aug 2017

Study sheds new light on gene fusion in bladder and brain cancer

A study by the University of Warwick sheds new light on gene fusion in bladder and brain cancer.

30 Aug 2017

Researchers develop new approach to efficiently produce versatile antibody therapies

A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy.

29 Aug 2017

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Scientists at Children's Hospital of Philadelphia report that a drug candidate that blocks abnormal protein signals may lead to the first pharmacologic treatment for hereditary multiple exostoses (HME), a rare pediatric genetic disease.

29 Aug 2017

Tiny tears in membranes of bone cells may be key to strong bones

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say.

29 Aug 2017

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

By combining new system-biological analyses and advanced data analysis, researchers at Karolinska Institutet have been able to monitor the maturation process of the immune system of leukemia patients who have undergone stem cell transplantation.

29 Aug 2017

Spaceflight causes many significant changes in the human body, research shows

A team of scientists from Russia and Canada has analyzed the effect of space conditions on the protein composition in blood samples of 18 Russian cosmonauts. The results indicated many significant changes in the human body caused by space flight.

29 Aug 2017

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

Parkinson's disease is an insidious disease: by the time it manifests as the typical motor dysfunctions such as tremors or muscle rigidity, portions of the brain have already been irreversibly destroyed.

29 Aug 2017

New antibodies may halt key pathological mechanisms across several neurological diseases

A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach.

29 Aug 2017

Study reveals new opportunities for treatment of Type 2 diabetes

Bacteria may be responsible for more than we suspect. Especially when it comes to inflammatory diseases such as Type 2 diabetes.

29 Aug 2017

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

The benefit of lowering low-density lipoprotein (LDL) cholesterol depends on how it is lowered, according to late-breaking results from a naturally randomised genetic trial presented today in a Hot Line - LBCT Session at ESC Congress1 and published in JAMA.

29 Aug 2017

Researchers explore freshwater turtles to understand mechanisms that protect from heart damage

In humans, going just minutes without oxygen-;such as during a heart attack or stroke-;can cause devastating damage to the heart.

29 Aug 2017

Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Targeting bone marrow protein could be effective way to improve stem cell transplants

Bone marrow contains hematopoetic stem cells, the precursors to every blood cell type. These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

28 Aug 2017

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G Protein News and Research

FDA makes the first gene therapy Kymriah available for treatment of pediatric ALL

MIT engineers devise automated approach to monitor neurons

Tips for packing nutritious, delicious, and affordable lunch

FDA approves first cell-based gene therapy for use in the United States

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Stabilizing TREM2 could be viable therapeutic strategy to combat Alzheimer's disease

Researchers demystify interdomain communication pathway in Hsp70 protein

Study sheds new light on gene fusion in bladder and brain cancer

Researchers develop new approach to efficiently produce versatile antibody therapies

Research may lead to first-ever pharmacological treatment for rare genetic bone disease

Tiny tears in membranes of bone cells may be key to strong bones

Extensive analysis reveals immune system dynamics after stem cell transplantation in leukemia patients

Spaceflight causes many significant changes in the human body, research shows

Bacterial community in the gut of Parkinson's patients differs from that of healthy people

New antibodies may halt key pathological mechanisms across several neurological diseases

Study reveals new opportunities for treatment of Type 2 diabetes

Clinical benefit of LDL cholesterol lowering therapies could depend on reduction in apoB particles

Researchers explore freshwater turtles to understand mechanisms that protect from heart damage

Research reveals LEGO-like stacking of protein complexes

Targeting bone marrow protein could be effective way to improve stem cell transplants

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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