Genetic Engineering News and Research

RSS

Genetically engineered kidney organoids solve mystery of a rare disease

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumors in patients with tuberous sclerosis complex (TSC).

6 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

Kyoto scientists reveal characteristic behaviors of erythropoietin-producing cells

A research team at Kyoto University has revealed characteristic behaviors of erythropoietin (Epo)-producing cells.

30 Jun 2022

New molecular information could help develop more effective treatments for melanoma

A new study reveals important molecular information that could help scientists develop more effective treatment and prevention strategies for a difficult-to-treat form of melanoma skin cancer.

24 Jun 2022

Non-traditional pet owners at increased risk of zoonotic diseases

Contact with non-traditional pets increases the risk of exposure to zoonotic pathogens, which are pathogens that spread between animals and people.

23 Jun 2022

Study offers new insight into the growth of blood vessels

Blood vessels must adapt their growth to the nutrients available in their surroundings so that they can keep organs adequately supplied. A team led by Michael Potente has identified two proteins that are important for this process and published their findings in Nature Metabolism.

20 Jun 2022

Study offers a new and unique treatment for AIDS

A new study from Tel Aviv University offers a new and unique treatment for AIDS which may be developed into a vaccine or a one time treatment for patients with HIV.

13 Jun 2022

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to treat the human condition according to data being presented Monday, June 13 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Advances in cellular immunotherapy that spur genetically modified T cells to attack cancer cells have revolutionized the treatment of certain blood cancers.

13 Jun 2022

Deciphering the structure of nuclear pore complex piece by piece

Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work.

10 Jun 2022

Using a harmless amoeba to protect children from dangerous infections

Innovative efforts at the University of Virginia School of Medicine to use a harmless amoeba to protect children from dangerous infections has won critical financial support from The Hartwell Foundation.

10 Jun 2022

Creating CAR T cells without an immune brake

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

Novel approach to drug repurposing incorporates two-stage prediction and machine learning

A new study presents a novel approach to drug repurposing that incorporates two-stage prediction and machine learning.

7 Jun 2022

Color-changing mouse model aids in better visualization of internal physiology

Biomedical and genetic engineers at Duke University and the Albert Einstein College of Medicine have developed a process to change the color of a mouse's tissue in imaging to better visualize its internal physiology.

6 Jun 2022

Molecular 'connector' may underlie gender differences in cocaine’s effects, mice study shows

Scientists have long known that cocaine works by latching on to molecular connectors on the surface of brain cells, allowing dopamine, a chemical that promotes feelings of pleasure and reward, to accumulate in the space between brain cells.

3 Jun 2022

Genetically engineered immune cells target cancer cells that may be responsible for leukemia relapse

Genetically engineered immune cells successfully target the specific cancer cells that may be responsible for relapse of acute myeloid leukemia (AML), a type of blood cancer, and proved effective in animal models of the disease, according to a preclinical study by investigators at Weill Cornell Medicine.

2 Jun 2022

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

Blocking an immune response-related enzyme holds promise in preventing or treating severe COVID-19 symptoms by reducing inflammation, tissue injury and blood clots in the lungs, new research in mice suggests.

1 Jun 2022

Genetically modified herpes virus can be used in the fight against cancer

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

1 Jun 2022

Novel mechanism to turn on cancer-killing T cells identified

Over the past decade, researchers have made great strides in the development and administration of cancer immunotherapies, which use the body's own immune system to treat disease.

25 May 2022

Genetic Engineering News and Research

Genetically engineered kidney organoids solve mystery of a rare disease

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

Kyoto scientists reveal characteristic behaviors of erythropoietin-producing cells

New molecular information could help develop more effective treatments for melanoma

Non-traditional pet owners at increased risk of zoonotic diseases

Study offers new insight into the growth of blood vessels

Study offers a new and unique treatment for AIDS

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Treatment with immunity-boosting protein enhances the function of CAR-T cells in fighting blood cancers

Deciphering the structure of nuclear pore complex piece by piece

Using a harmless amoeba to protect children from dangerous infections

Creating CAR T cells without an immune brake

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

Novel approach to drug repurposing incorporates two-stage prediction and machine learning

Color-changing mouse model aids in better visualization of internal physiology

Molecular 'connector' may underlie gender differences in cocaine’s effects, mice study shows

Genetically engineered immune cells target cancer cells that may be responsible for leukemia relapse

Inhibiting immune response-related enzyme holds promise in preventing or treating severe COVID-19

Genetically modified herpes virus can be used in the fight against cancer

Novel mechanism to turn on cancer-killing T cells identified

Biochemistry eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo