Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant.

11 Apr 2016

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Patients treated with CMX-2043--an investigational drug that has previously shown some ability to protect heart muscle from damage during stenting--saw no improved protection in their kidneys compared to placebo, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

5 Apr 2016

Researchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy aging

The average life expectancy in the United States is approximately 78 years old. Americans live longer, with better diets and improved health care, than ever before, but only 0.02 percent will hit the century mark.

30 Mar 2016

New report offers startling statistics about chronic kidney disease in the U.S.

A sweeping new report assessing chronic kidney disease in the United States offers startling statistics about a condition that affects almost 14 percent of the U.S. population and costs billions in Medicare spending each year.

30 Mar 2016

New thematic issue highlights link between hyperuricemia, gout and kidney disease

The increasing prevalence of both gout and chronic kidney disease has led to a growing interest in the association between hyperuricemia (an abnormally high level of uric acid in the blood) and kidney disease.

29 Mar 2016

Wnt secretion inhibitors may reduce renal fibrosis

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease to progressively worsen.

25 Mar 2016

Common genetic defect in beta cells may underlie both known forms of diabetes

New research by Dr. Sylvie Lesage, scientist at Maisonneuve-Rosemont Hospital and associate research Professor at University of Montreal, just published in the prestigious international scientific journal Nature Genetics, has discovered that a common genetic defect in beta cells may underlie both known forms of diabetes.

25 Mar 2016

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

University of Alabama at Birmingham researchers have made a microscopic snapshot of the early renal lipid changes in acute kidney injury, using the laser-scanning method called MALDI tissue imaging to localize the changes.

24 Mar 2016

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry, investigators at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD).

21 Mar 2016

Sodium MRI could provide more detailed picture of tissue health and disease

MRI experts at The University of Nottingham win £1m grant to adapt scanning techniques to pick up sodium in the body. The research could lead to much more detailed MRI scans in the future with significant improvements to the diagnosis and treatment of many diseases.

18 Mar 2016

Study could lead to potential new therapeutic target with fewer side effects for hypertension

A team of Vermont investigators has been issued a patent for their discovery of a molecule that rescues damaged blood vessels, yet preserves healthy vessels and could serve as a springboard for a new pharmaceutical therapy with fewer side effects for hypertension - a major risk factor for cardiovascular and kidney disease that effects roughly one in three people in the U.S.

15 Mar 2016

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

On World Kidney Day, leading experts from the European ADPKD Forum today issue a collaborative letter to over 350 European decision makers (European Parliament, European Commission, Council representatives) celebrating the year one progress of the Brussels Declaration on ADPKD, while calling for urgent backing from policy makers to reduce the widespread inequalities and variations in care that remain.

10 Mar 2016

World Kidney Day 2016 focuses on children

On Thursday March 10th we are celebrating the 11th edition of World Kidney Day (WKD), a joint initiative organized by the International Society of Nephrology (ISN) and the International Federation of Kidney Foundations (IFKF).

10 Mar 2016

Pioneering progress on ADPKD: an interview with Tess Harris

ADPKD is a chronic, progressive and inherited kidney disease characterized by fluid-filled cysts that develop in the kidneys and other organs. It is the most common inherited kidney disease, and affects millions worldwide.

10 Mar 2016

Renal risk factors for NA-treated HBV patients identified

A South Korean research team has identified several clinical and medical factors associated with renal function decline in patients with chronic hepatitis B virus infection treated with oral nucleos(t)ide analogues.

10 Mar 2016

Resistance to prior antiviral agents impacts TDF response

Taiwanese researchers find that virological response to tenofovir disoproxil fumarate in treatment-experienced patients with chronic hepatitis B virus infection can vary depending on the nucleos(t)ide analogue the patient is resistant to.

10 Mar 2016

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).

10 Mar 2016

Physicians miss opportunities for detection and management of people with prediabetes

Less than one-quarter of patients who met the criteria for prediabetes received drug or lifestyle modification treatment from their primary care physician, according to University of Florida researchers, who say the findings indicate physicians are missing opportunities for diabetes prevention.

9 Mar 2016

Preterm neonatal progenitor cells may be a powerful tool for regeneration of damaged kidneys

Cells collected noninvasively from the urine of preterm infants may lead to breakthroughs in regenerative kidney repair for patients with kidney disease and injury, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

4 Mar 2016

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

A new study examines whether recent changes in the use of anemia drugs for patients on dialysis have contributed to changes in rates of death or cardiovascular events. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, indicate that these risks appear to be decreasing for patients on dialysis as well as for older adults (Medicare beneficiaries) who are not on dialysis.

27 Feb 2016

Nephropathy News and Research

Further Reading

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Investigational drug provides no improved protection to patients with contrast-induced acute kidney injury

Researchers to study people over 100 years old in Acciaroli, Italy to unlock secrets of healthy aging

New report offers startling statistics about chronic kidney disease in the U.S.

New thematic issue highlights link between hyperuricemia, gout and kidney disease

Wnt secretion inhibitors may reduce renal fibrosis

Common genetic defect in beta cells may underlie both known forms of diabetes

MALDI tissue imaging spots early renal lipid changes in acute kidney injury

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

Sodium MRI could provide more detailed picture of tissue health and disease

Study could lead to potential new therapeutic target with fewer side effects for hypertension

EAF celebrates first anniversary of Brussels Declaration on ADPKD, urges MEPs to unite for better patient care

World Kidney Day 2016 focuses on children

Pioneering progress on ADPKD: an interview with Tess Harris

Renal risk factors for NA-treated HBV patients identified

Resistance to prior antiviral agents impacts TDF response

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

Physicians miss opportunities for detection and management of people with prediabetes

Preterm neonatal progenitor cells may be a powerful tool for regeneration of damaged kidneys

Changes in use of anemia drugs affects risk of death or cardiovascular events in dialysis patients

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