Peptides News and Research

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Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for developing new antibiotic treatments.

2 Jul 2024

Nanorobots with hidden weapons for precision cancer therapy

Researchers at Karolinska Institutet in Sweden have developed nanorobots that kill cancer cells in mice.

1 Jul 2024

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

27 Jun 2024

Study finds women lost more of their body weight on average with semaglutide than men

Researchers performed a secondary analysis of the semaglutide treatment effect in people with obesity and heart failure with a preserved left ventricular ejection fraction program that included individuals with diabetes mellitus, stratified by biological sex.

26 Jun 2024

New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Semaglutide provides double benefit for women with heart failure

Semaglutide, a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options.

24 Jun 2024

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

A new paper from an interdisciplinary team at MUSC Hollings Cancer Center describes how the bacteria Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy, allowing oral cancer tumors to become resistant to the drug's effects.

18 Jun 2024

Deep learning revives ancient peptides to battle antibiotic resistance

Researchers used deep learning to resurrect antibiotic peptides from extinct organisms, offering new solutions for combating antibiotic resistance.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Discovery could accelerate efforts to produce new antibiotics in the fight against antimicrobial resistance

A discovery made by scientists at King's College London could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.

10 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Simple peptide modification could unlock a whole class of targets for drug discovery

A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.

7 Jun 2024

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.

6 Jun 2024

Oral insulin drops offer needle-free alternative for diabetes management

Diabetes rates continue to rise, with 11.7 million Canadians living with diabetes or pre-diabetes. At UBC, scientists have created a pain-free drug delivery method to help people with diabetes manage the disease and maintain their health more easily.

5 Jun 2024

Artificial intelligence accelerates natural-product antibiotic discovery

Almost a century ago, the discovery of antibiotics like penicillin revolutionized medicine by harnessing the natural bacteria-killing abilities of microbes.

5 Jun 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge of essential cell functions.

29 May 2024

Proline-based nano cages offer targeted drug delivery, limit side effects of chemotherapy

A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.

29 May 2024

Secarna Pharmaceuticals and Orbit Discovery enter collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide therapeutics

Secarna Pharmaceuticals GmbH & Co. KG (Secarna), a leading independent European antisense drug discovery and development company, and Orbit Discovery Ltd. (Orbit), a leader in the discovery of therapeutic peptide hits, today announced that they have entered into a collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide (ASO) therapeutics.

From Secarna Pharmaceuticals 29 May 2024

Study identifies key gluten peptide triggering leaky gut in celiac patients

Today is International Celiac Day. Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population.

17 May 2024

Peptides News and Research

Antimicrobial peptide mixtures: A viable approach to long-lasting antibiotic treatments

Nanorobots with hidden weapons for precision cancer therapy

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Study finds women lost more of their body weight on average with semaglutide than men

New enzyme targets hold promise for cancer therapies

Semaglutide provides double benefit for women with heart failure

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

Deep learning revives ancient peptides to battle antibiotic resistance

UD researchers pioneer universal, economical method for proteomics sample preparation

Discovery could accelerate efforts to produce new antibiotics in the fight against antimicrobial resistance

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Simple peptide modification could unlock a whole class of targets for drug discovery

Antibacterial lipopeptide shown to be highly effective in killing Staphylococcus aureus

Oral insulin drops offer needle-free alternative for diabetes management

Artificial intelligence accelerates natural-product antibiotic discovery

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Proline-based nano cages offer targeted drug delivery, limit side effects of chemotherapy

Secarna Pharmaceuticals and Orbit Discovery enter collaboration to discover and develop peptide-conjugated targeted antisense oligonucleotide therapeutics

Study identifies key gluten peptide triggering leaky gut in celiac patients

Editorial Focus eBook - Peptides and Oligonucleotides (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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