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Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

A recent study assessed the role of the SARS-CoV-2 Omicron spike H655Y mutation on viral entry pathways.

24 Mar 2022

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Researchers evaluated the stability and expression of mutations in the spike protein of SARS-CoV-2.

24 Mar 2022

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

Sino Biological is pleased to announce a CRO services partnership with Ainnocence, Inc. of San Jose, California.

From Sino Biological Inc. 24 Mar 2022

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers demonstrate the broad neutralization potential of a strategically engineered circRNA using mice as a model system.

21 Mar 2022

Biological timeline of COVID-19 immune recovery described in new research

In a recent study published on the bioRxiv* preprint server, a group of researchers from the University of California, San Francisco, looked at intra-patient immunological changes over time to see if there were any changes in immune responses associated with successful COVID-19 resolution.

21 Mar 2022

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Researchers evaluated the underlying cellular mechanisms of SARS-CoV-2-induced olfactory epithelium damage in golden Syrian hamsters.

18 Mar 2022

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Researchers demonstrated that the thiopurines block coronaviruses spike protein assembly and integration into progeny virions.

17 Mar 2022

Novel targets to inhibit SARS-CoV-2 variants

A new study identified additional targets on SARS-CoV-2 proteins to prevent the emergence of new SARS-CoV-2 variants of concern.

16 Mar 2022

Sino Biological Invests Over 200M RMB to Establish New Subsidiaries in Taizhou and Suzhou, China.

Sino Biological is pleased to announce the formation of two new operationally-focused subsidiaries in China.

From Sino Biological Inc. 14 Mar 2022

Antibody treatment improves symptoms of neuromyelitis optica in a rat model

Autoimmune diseases are the molecular equivalent of "friendly fire": the body attacks itself instead of harmful invaders.

11 Mar 2022

Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Researchers observed that Golgi fragmentation induced by SARS-CoV-2 facilitates viral trafficking.

11 Mar 2022

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Researchers elucidated antiviral activities of aminoglycoside geneticin against seven SARS-CoV-2 variants using different cell lines and respiratory tissues.

11 Mar 2022

CRIPSR identifies cell-type-specific ACE2 modifiers

Researchers compile a list of candidate genes to identify the surface abundance of functional regulators of ACE2.

9 Mar 2022

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

A new study has focused on developing a novel anti-SARS-CoV-2 therapy using HTA directed against the human host DEAD-box RNA helicase.

3 Mar 2022

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases.

2 Mar 2022

Biophysical fitness profile of SARS-CoV-2 Delta variant

In a recent study posted to the bioRxiv* preprint server, researchers investigated the biophysical fitness landscape of the receptor-binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

1 Mar 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

Protein Expression News and Research

Study finds that Omicron variant preferentially uses the endosome pathway through mutation in the spike protein

Study evaluates mutation-induced SARS-CoV-2 spike protein fold stability

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Biological timeline of COVID-19 immune recovery described in new research

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Novel targets to inhibit SARS-CoV-2 variants

Sino Biological Invests Over 200M RMB to Establish New Subsidiaries in Taizhou and Suzhou, China.

Antibody treatment improves symptoms of neuromyelitis optica in a rat model

Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

CRIPSR identifies cell-type-specific ACE2 modifiers

Study shows targeting DDX3 with RK-33 reduced the viral load in four isolates of SARS-CoV-2

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Biophysical fitness profile of SARS-CoV-2 Delta variant

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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