Spectrometry News and Research

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Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

Researchers identify distinct gut microbiome metabolites in women with endometriosis, offering potential for non-invasive diagnosis and new therapies.

14 Oct 2024

New insights on protein degraders open doors to treatment for 'undruggable' diseases

Researchers at the University of Dundee have revealed in the greatest detail yet the workings of molecules called 'protein degraders' which can be deployed to combat what have previously been regarded as 'undruggable' diseases, including cancers and neurodegenerative diseases.

12 Oct 2024

New computational pipeline revolutionizes personalized cancer vaccine design

Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular targets of T cells and harnesses artificial intelligence algorithms to use its output to design personalized cancer vaccines for patients.

12 Oct 2024

Study unveils new molecular switch protecting cells from death

Researchers at LMU University Hospital have discovered a new molecular switch that protects against cell death.

12 Oct 2024

Decoding Cannabis: Differentiating Hemp and Marijuana

In this interview conducted at Pittcon 2024 in San Diego, Rabi Musah delves into her innovative use of DART-HRMS and chemometric analysis to differentiate between hemp and marijuana varieties of Cannabis sativa, exploring the forensic and legal implications of these findings.

From Pittcon 10 Oct 2024

Unexpected benzene levels in popular acne and rosacea products

Investigators have determined that a substantial portion of topical benzoyl peroxide (BPO) acne and rosacea treatments currently on the market are unstable and contain unacceptably high levels of benzene, a known human carcinogen.

7 Oct 2024

Researchers uncover secret to regulating the body's internal clock

Scientists from Duke-NUS Medical School and the University of California, Santa Cruz, have discovered the secret to regulating our internal clock.

7 Oct 2024

Researchers boost natural defenses to fight cataracts and delay the need for surgery

Researchers have reviewed strategies to increase glutathione levels in the eye lens, focusing on endogenous molecular mechanisms to prevent cataracts by countering oxidative stress.

3 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

High levels of microplastics found in prostate tumors, possibly linked to take-out food

Researchers discovered microplastics in both tumor and para-tumor prostate tissues, with higher concentrations found in tumor samples, raising concerns about their potential role in cancer development.

1 Oct 2024

New breath-based test for lower respiratory tract infections shows 100% sensitivity in critical care settings

Researchers have developed a breath-based in vitro assay that accurately detects lower respiratory tract infections (LRTIs) by measuring neutrophil elastase activity. This non-invasive test offers high diagnostic sensitivity and could revolutionize LRTI detection.

29 Sep 2024

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

Scientists from the University of Copenhagen have detected lipid biomarkers in children and teenagers with obesity that indicate an increased risk of developing type 2 diabetes, liver and heart disease as adults.

20 Sep 2024

New blood test identifies obesity-related health risks in children

A new type of blood test using lipids could make it easier to identify children at risk of complications around obesity including type two diabetes, liver and heart disease, say scientists.

20 Sep 2024

Researchers discover how oral cancer cells may block the body's immune response

Macquarie University researchers have discovered new information about how oral cancer cells may block the body's immune response. This could lead to better treatments for this aggressive disease.

18 Sep 2024

New insights into the mechanisms of efavirenz-induced neurotoxicity

Efavirenz is an important drug for treating HIV infection, but it has negative effects that can significantly impact patients' quality of life over time. It causes neuropsychiatric disorders and neurocognitive impairment in roughly 50 percent of patients. The drug is associated with abnormal lipid levels in blood plasma, but the molecular mechanisms responsible for negative clinical observations are unknown.

18 Sep 2024

Research reveals only a few brain regions remain untouched by transition to motherhood

Research shows pregnancy triggers neuroanatomical changes in the brain, with decreased cortical volume and increased white matter integrity over gestation.

17 Sep 2024

Salt can boost antitumor responses of T cells

Elevated sodium levels in tumors boost T-cell metabolic fitness and cytotoxicity, revealing potential avenues for improving cancer therapies.

13 Sep 2024

Early lifestyle changes lead to lasting impacts on metabolism

A new study from the University of Eastern Finland (UEF) uncovers how early lifestyle changes can have long-lasting impacts.

12 Sep 2024

New IndiPHARM initiative aims to revolutionize personalized medication management

A Columbia University-led multicenter research effort called IndiPHARM: individual metabolome and exposome assessment for pharmaceutical optimization will develop a platform and monitoring system to prevent unwanted interactions between medications and other environmental, genetic, and lifestyle factors, in order to optimize therapeutic efficacy.

12 Sep 2024

Cruciferous vegetables like broccoli reduce blood pressure compared to root and squash vegetables

Daily intake of cruciferous vegetables significantly lowers blood pressure in mildly hypertensive adults, highlighting their role in cardiovascular health.

10 Sep 2024

Spectrometry News and Research

Distinct fecal metabolites identified for non-invasive diagnosis of endometriosis

New insights on protein degraders open doors to treatment for 'undruggable' diseases

New computational pipeline revolutionizes personalized cancer vaccine design

Study unveils new molecular switch protecting cells from death

Decoding Cannabis: Differentiating Hemp and Marijuana

Unexpected benzene levels in popular acne and rosacea products

Researchers uncover secret to regulating the body's internal clock

Researchers boost natural defenses to fight cataracts and delay the need for surgery

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

High levels of microplastics found in prostate tumors, possibly linked to take-out food

New breath-based test for lower respiratory tract infections shows 100% sensitivity in critical care settings

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

New blood test identifies obesity-related health risks in children

Researchers discover how oral cancer cells may block the body's immune response

New insights into the mechanisms of efavirenz-induced neurotoxicity

Research reveals only a few brain regions remain untouched by transition to motherhood

Salt can boost antitumor responses of T cells

Early lifestyle changes lead to lasting impacts on metabolism

New IndiPHARM initiative aims to revolutionize personalized medication management

Cruciferous vegetables like broccoli reduce blood pressure compared to root and squash vegetables

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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