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Research shows enlarged genotype-phenotype correlation for three-base pair deletion in NF1

International collaborative research led by Ludwine Messiaen, Ph.D., shows that while a three-base pair, in-frame deletion called p.Met992del in the NF1 gene has a mild phenotype for people with the genetic disorder neurofibromatosis type 1, or NF1, the mutation does cause complications.

18 Sep 2018

Day-tripping to the dispensary: Seniors in pain hop aboard the canna-bus

Shirley Avedon, 90, had never been a cannabis user. But carpal tunnel syndrome that sends shooting pains into both of her hands and an aversion to conventional steroid and surgical treatments is prompting her to consider some new options.

18 Sep 2018

Machine learning program could distinguish between two lung cancer types

A new computer program can analyze images of patients' lung tumors, specify cancer types, and even identify altered genes driving abnormal cell growth, a new study shows.

17 Sep 2018

Salk research in yeast leads to serendipitous finding about hypomyelinating leukodystrophy

Studying the fundamental aspects of biology can sometimes lead to unexpected findings that directly relate to human disease. In one of the latest examples of scientific serendipity, researchers from the Salk Institute found that an important quality control mechanism in baker's yeast is closely connected to hypomyelinating leukodystrophy, a debilitating disease found in children.

17 Sep 2018

Kessler Foundation joins new study to improve cognition in people with progressive MS

Nancy Chiaravalloti, PhD, and John DeLuca, PhD, have been awarded a $410,000 grant from the Multiple Sclerosis Society of Canada and the MS Scientific ResearchFoundation to assess the efficacy of a mixed-method intervention to improve cognition in people with progressive MS.

14 Sep 2018

Researchers identify a new cause of chronic stress in the brain

In an international collaboration between MedUni Vienna, Semmelweis University in Budapest, the Karolinska Institute in Stockholm and Yale University in the USA, researchers have identified a new process in the brain that is responsible for the delayed stress response and the long-term effects of stress: with a delay of 10 minutes after the "danger", the area of the brain that reacts to stress and responsible for further action is activated via the cerebral fluid.

14 Sep 2018

Scientists get unprecedented view of brain development through high-resolution genomic map

Researchers at St. Jude Children's Research Hospital have created a massive database of the changes in gene activity of individual cells in the cerebellum during embryonic development and immediately after birth.

14 Sep 2018

Discovery of key mechanism may lead to more functional skin grafts for burn victims

University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.

14 Sep 2018

Breakthrough shows immune cells may play a role in schizophrenia

A type of immune cell called the “macrophages” are known to be one of the first soldiers of the body that can fight off infections and plays a role in maintaining immunity and in inflammation. According to latest research in schizophrenia, these macrophages can become altered and may cause changes in the brain leading to changes in the brain similar to schizophrenia.

14 Sep 2018

Study uncovers four neuron types in the peripheral auditory system

Researchers at Karolinska Institutet have identified four types of neurons in the peripheral auditory system, three of which are new to science.

12 Sep 2018

Male and female brains are affected differently by repeated binge drinking

Gene expression in an area of the brain linked to addiction is affected differently by repeated binge drinking in males and females, finds a new study published today in Frontiers in Genetics.

10 Sep 2018

Scientists discover key aspect in the development of multiple sclerosis

In multiple sclerosis, not only the T cells of the immune system, but also its B cells, play an important role.

7 Sep 2018

Mimicking Human Brain Development Using Organoids

Dr. Paul Tesar from the Tesar Laboratory at Case Western University, Ohio, discusses the importance of organoids in biological research and the development of organoids which are capable of simulating the early stages of human myelin.

7 Sep 2018

Study links spinal muscular atrophy disease expression with haplotypes

A natural history study has provided the first comprehensive clinical description of spinal muscular atrophy within the Amish and Mennonite communities and correlates ancestral chromosome 5 haplotypes and SMN2 copy number with disease severity.

7 Sep 2018

Newly discovered marker can identify patients who would benefit from novel asthma treatments

Researchers at RCSI, Stanford University and Oregon Health Sciences University have discovered a marker which can help determine which asthma patients are likely to benefit from a new treatment which targets inflammatory cells called Eosinophils.

6 Sep 2018

Doctor with Guillain Barré syndrome recovers back to normal life

Doctors do the darndest things. Take the one who walked right up to Dan Thomas, MD, at a lecture, got into the ready position, and proceeded to perform several squats as Thomas watched, puzzled.

6 Sep 2018

Denser airway nerves connected with more severe asthma symptoms

A new study implicates remodeling of nerves in the airways as a key contributor to heightened sensitivity and airway constriction in patients with asthma.

6 Sep 2018

Medical marijuana may alter brain connections to provide relief from chronic nerve pain

When medical marijuana is taken for chronic nerve pain, it may provide pain relief by reducing connections between the areas of the brain that process emotions and sensory signals, according to a study published in the September 5, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

6 Sep 2018

UCLA Seizure Disorder Center offers hope to patients with drug-resistant epilepsy

More than 20 new anti-seizure drugs have been introduced in recent decades - a number that means little to people with drug-resistant epilepsy. For them, treatment has not improved.

6 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

Nerve News and Research

Research shows enlarged genotype-phenotype correlation for three-base pair deletion in NF1

Day-tripping to the dispensary: Seniors in pain hop aboard the canna-bus

Machine learning program could distinguish between two lung cancer types

Salk research in yeast leads to serendipitous finding about hypomyelinating leukodystrophy

Kessler Foundation joins new study to improve cognition in people with progressive MS

Researchers identify a new cause of chronic stress in the brain

Scientists get unprecedented view of brain development through high-resolution genomic map

Discovery of key mechanism may lead to more functional skin grafts for burn victims

Breakthrough shows immune cells may play a role in schizophrenia

Study uncovers four neuron types in the peripheral auditory system

Male and female brains are affected differently by repeated binge drinking

Scientists discover key aspect in the development of multiple sclerosis

Mimicking Human Brain Development Using Organoids

Study links spinal muscular atrophy disease expression with haplotypes

Newly discovered marker can identify patients who would benefit from novel asthma treatments

Doctor with Guillain Barré syndrome recovers back to normal life

Denser airway nerves connected with more severe asthma symptoms

Medical marijuana may alter brain connections to provide relief from chronic nerve pain

UCLA Seizure Disorder Center offers hope to patients with drug-resistant epilepsy

Hypertension drugs may be used to preserve memory of lupus patients

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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