Proliferation News and Research

RSS

Promising technique for treating eye disease proves effective in preclinical studies

A promising technique for treating human eye disease has proven effective in preclinical studies and may lead to new treatments to prevent blindness, according to experiments conducted at The Scripps Research Institute in La Jolla, California.

23 Oct 2013

P400 predicts RCC outcome

Reduced expression of a senescence-associated protein is associated with worse outcome in patients with renal cell carcinoma, study findings show.

22 Oct 2013

Scientists highlight novel way to develop universal influenza vaccine that can protect against multiple flu strains

A study led by St. Jude Children's Research Hospital scientists highlights a new approach for developing a universal influenza vaccine that could protect against multiple flu strains, including deadly pandemic strains. The research appears today in the advance online edition of the scientific journal Nature Immunology.

22 Oct 2013

Verastem presents positive results from VS-6063 clinical and preclinical studies at 2013 AACR-NCI-EORTC meeting

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced positive results from the Phase 1 portion of its Phase 1/1b study of defactinib (VS-6063) in combination with paclitaxel in patients with ovarian cancer that were presented at the 2013 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston.

21 Oct 2013

Cell Therapeutics presents preclinical study results of PIXUVRI at AACR-NCI-EORTC meeting

Cell Therapeutics, Inc. (CTI) today announced the presentation of findings from a preclinical study of PIXUVRI® (pixantrone) that suggest its mechanism of inducing tumor cell death is novel and distinct from that of anthracyclines such as doxorubicin.

21 Oct 2013

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

LEE011, a small-molecule inhibitor of cyclin-dependent kinases (CDK) 4/6 being developed by Novartis Oncology, showed promising results in drug-resistant melanoma and drug-resistant breast cancer when tested in combination with other targeted therapies, and based on these preclinical results, several phase I clinical trials were launched recently, according to results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held October 19-23.

21 Oct 2013

Study: Pds5 proteins modulate behavior of cohesins to ensure proper division of cells

Cohesins are protein complexes that join the two copies of each chromosome-called sister chromatids-to ensure that they are shared fairly between the daughter cells during cell division. In this way, each daughter cell receives exactly the same genetic information from the parent cell.

19 Oct 2013

Researchers find novel drug target for anaplastic thyroid carcinomas

Anaplastic thyroid carcinomas are aggressive tumors that do not respond to traditional radio- or chemotherapeutic agents, and there currently is no cure or effective treatment available. Median survival from diagnosis is 5 months, and although ATC accounts for only 1.7% of all thyroid cancers in the U.S., it is responsible for a large proportion of thyroid cancer-related deaths.

17 Oct 2013

Study provides novel link between cellular aging and diffuse large B-cell lymphoma

Scientists at the University of Massachusetts Medical School have shown that diffuse large B-cell lymphoma (DLBCL) may be susceptible to treatment by re-activating the normal aging program in tumor cells so they can no longer divide.

15 Oct 2013

First Edition: October 11, 2013

Today's headlines include news about what experts are diagnosing as the trouble spots in the federal online health insurance exchange and how to fix them.

11 Oct 2013

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

In an unprecedented move, the California Academy of Sciences today will induct two scientists from the Gladstone Institutes', President R. Sanders "Sandy" Williams, MD, and Investigator Katherine Pollard, PhD, as Academy Fellows, bestowing yet another honor on two of San Francisco's most esteemed scientists.

11 Oct 2013

Genetic mutation that protects skin from UV radiation may cause testicular cancer in Caucasian

A Ludwig Cancer Research study published in Cell today identifies a common mutation that dramatically increases the risk for testicular cancer—and describes a likely molecular mechanism by which it exerts that effect.

11 Oct 2013

Small interfering RNAs in mammals act as specific antiviral weapons

Many viral infections are nipped in the bud by the innate immune response. This involves specific proteins within the infected cell that recognize the virus and trigger a signalling cascade - the so-called interferon response. This activates a protective mechanism in neighbouring cells and often results in the death of the primarily infected cell.

11 Oct 2013

Diverse Neurological Disorders Appear To Share Tangled Metabolic Roots

...

10 Oct 2013

High levels of HDL have been linked to increased breast cancer risks, enhance cancer aggressiveness

High levels of high density lipoprotein (HDL), also known as the "good cholesterol," are thought to protect against heart disease. However, what's good for one disease may not be good for another.

10 Oct 2013

CNIO researcher identifies new molecular mechanism that regulates genome stability, cell proliferation

Cell division is an essential process for the development of an organism. This process, however, can cause tumour growth when it stops working properly. Tumour cells accumulate alterations in their genetic material, and this makes them divide in an uncontrolled fashion, thus encouraging growth of the tumour.

9 Oct 2013

Epigenetic regulation linked with pathogenesis of Alzheimer's disease

New evidence presented at the 26th ECNP Congress linking epigenetic regulation with Alzheimer's disease may one day lead to new early diagnostic tests and even novel treatment options for the most common form of dementia.

7 Oct 2013

Active ingredient of ipecac syrup inhibits growth of cancer cells

An old home remedy called ipecac syrup, once stocked in medicine cabinets in case of accidental poisoning, is showing promise as a new chemotherapy drug for bladder cancer.

4 Oct 2013

Researchers suggest new view of how stem cells may help repair brain following trauma

University of South Florida researchers have suggested a new view of how stem cells may help repair the brain following trauma. In a series of preclinical experiments, they report that transplanted cells appear to build a "biobridge" that links an uninjured brain site where new neural stem cells are born with the damaged region of the brain.

4 Oct 2013

Scientists identify new drug for inherited form of cancer with no known cure

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure.

3 Oct 2013

Proliferation News and Research

Promising technique for treating eye disease proves effective in preclinical studies

P400 predicts RCC outcome

Scientists highlight novel way to develop universal influenza vaccine that can protect against multiple flu strains

Verastem presents positive results from VS-6063 clinical and preclinical studies at 2013 AACR-NCI-EORTC meeting

Cell Therapeutics presents preclinical study results of PIXUVRI at AACR-NCI-EORTC meeting

New small-molecule inhibitor shows promising results in drug-resistant melanoma, breast cancer

Study: Pds5 proteins modulate behavior of cohesins to ensure proper division of cells

Researchers find novel drug target for anaplastic thyroid carcinomas

Study provides novel link between cellular aging and diffuse large B-cell lymphoma

First Edition: October 11, 2013

Two scientists from Gladstone Institutes recognized for their contributions to science, medicine

Genetic mutation that protects skin from UV radiation may cause testicular cancer in Caucasian

Small interfering RNAs in mammals act as specific antiviral weapons

Diverse Neurological Disorders Appear To Share Tangled Metabolic Roots

High levels of HDL have been linked to increased breast cancer risks, enhance cancer aggressiveness

CNIO researcher identifies new molecular mechanism that regulates genome stability, cell proliferation

Epigenetic regulation linked with pathogenesis of Alzheimer's disease

Active ingredient of ipecac syrup inhibits growth of cancer cells

Researchers suggest new view of how stem cells may help repair brain following trauma

Scientists identify new drug for inherited form of cancer with no known cure

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News