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Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Pyroptosis, a highly inflammatory type of programmed cell death, has garnered attention for its potential in cancer treatment.

3 Mar 2025

Talk therapy delivered by non-specialists effective for pregnant and postpartum individuals

Approximately one in five of pregnant and postpartum individuals experience depression and anxiety, yet less than 10 per cent receive proper treatment.

3 Mar 2025

Hallucinogen use linked to increased risk of mortality in emergency care patients

People seeking emergency care for hallucinogen use were at 2.6-fold higher risk of death within 5 years than the general population, according to a new study published in CMAJ.

3 Mar 2025

Co-occurring mutations may limit effectiveness of KRAS G12C inhibitors in colorectal and pancreatic cancer

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic alterations that can be associated with resistance to KRAS G12C inhibitors, despite no prior treatment with this therapy, according to recent results from a large multidatabase analysis.

3 Mar 2025

Targeting SSAT enzyme offers new hope for psoriasis treatment

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting around 250,000 people in Austria.

3 Mar 2025

Medtronic receives FDA approval for BrainSense Adaptive DBS technology

For the one million people diagnosed with Parkinson's disease in the United States, Medtronic plc (NYSE:MDT), a global leader in healthcare technology, proudly announces U.S. Food and Drug Administration (FDA) approval of BrainSense™ Adaptive deep brain stimulation (aDBS) and BrainSense™ Electrode Identifier (EI).

3 Mar 2025

Pioneering the world’s first CRISPR medicine for sickle cell disease

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters was with a 24-year-old patient whose sickle cell disease left them with almost weekly pain episodes.

3 Mar 2025

Omalizumab outperforms oral immunotherapy in treating multi-food allergy

A clinical trial has found that the medication omalizumab, marketed as Xolair, treated multi-food allergy more effectively than oral immunotherapy (OIT) in people with allergic reactions to very small amounts of common food allergens.

2 Mar 2025

St. Jude scientists discover how retinoic acid selectively kills metastatic neuroblastoma cells

Neuroblastoma is a solid tumor that occurs in children. When high-risk, the disease has a poor prognosis. Decades ago, adding the drug retinoic acid to neuroblastoma treatment increased survival by 10-15%.

2 Mar 2025

Understanding the benefits and risks of hyperbaric oxygen therapy

Hyperbaric oxygen therapy is well known for treating scuba and deep-sea divers affected by the rapid change in pressure around them. But did you know that HBOT is also used to treat a variety of other health problems, including carbon monoxide poisoning and diabetic foot ulcers?

28 Feb 2025

Study demonstrates successful gene therapy for maple syrup urine disease

A study led by UMass Chan researchers demonstrated that a gene therapy to correct a mutation that causes maple syrup urine disease (MSUD) prevented newborn death, normalized growth, restored coordinated expression of the affected genes and stabilized biomarkers in a calf as well as in mice.

28 Feb 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

Stress & Distress: Designing clinical trials for maximum efficacy

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

Atlantia Clinical Trials investigates the role of microbiomes in immunity, focusing on gut and lung interactions to develop innovative health solutions.

From Atlantia Clinical Trials 28 Feb 2025

UCSF study reveals lungs as source of hematopoietic stem cells

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing.

28 Feb 2025

Nanoplatform strategy for multimodal cancer therapy and tumor visualization

Announcing a new publication for Acta Materia Medica journal. Treatment of cancer can be challenging, because of the disease's intricate and varied nature.

27 Feb 2025

New ASTRO guideline offers radiation therapy recommendations for anal cancer

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance on the use of radiation therapy to treat adult patients with primary squamous cell carcinoma (SCC) of the anal canal and anal margin.

27 Feb 2025

Study: One in eight African hospital patients critically ill with high mortality

One in eight patients in hospitals in Africa is critically ill, and one in five of the critically ill die within a week, according to a new study in The Lancet.

27 Feb 2025

$4.9 million grant aims to enhance PTSD treatment using MDMA and psychotherapy

Researchers at The University of Texas Health Science Center at San Antonio and their collaborators at Emory University have received a $4.9 million grant aimed at significantly improving treatment and recovery rates for individuals suffering from post-traumatic stress disorder.

27 Feb 2025

New gene therapy strategy could cure COPA Syndrome

Scientists compared five families and multiple generations to find a gene variant that prevents COPA Syndrome and opens the door to a new gene therapy for the condition.

27 Feb 2025

Therapy News and Research

Study elucidates mechanism connecting ER membrane remodeling to pyroptosis in cancer cells

Talk therapy delivered by non-specialists effective for pregnant and postpartum individuals

Hallucinogen use linked to increased risk of mortality in emergency care patients

Co-occurring mutations may limit effectiveness of KRAS G12C inhibitors in colorectal and pancreatic cancer

Targeting SSAT enzyme offers new hope for psoriasis treatment

Medtronic receives FDA approval for BrainSense Adaptive DBS technology

Pioneering the world’s first CRISPR medicine for sickle cell disease

Omalizumab outperforms oral immunotherapy in treating multi-food allergy

St. Jude scientists discover how retinoic acid selectively kills metastatic neuroblastoma cells

Understanding the benefits and risks of hyperbaric oxygen therapy

Study demonstrates successful gene therapy for maple syrup urine disease

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

Stress & Distress: Designing clinical trials for maximum efficacy

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

UCSF study reveals lungs as source of hematopoietic stem cells

Nanoplatform strategy for multimodal cancer therapy and tumor visualization

New ASTRO guideline offers radiation therapy recommendations for anal cancer

Study: One in eight African hospital patients critically ill with high mortality

$4.9 million grant aims to enhance PTSD treatment using MDMA and psychotherapy

New gene therapy strategy could cure COPA Syndrome

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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