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Will new hepatitis C treatments strain payers’ budgets? An interview with Dr Chhatwal

Our analysis shows that these drugs would not save overall healthcare money, but would add to the budget. When something is cost effective, it does not necessarily mean it is going to save money. It essentially implies that we're willing to spend additional money to gain additional benefits...

28 Apr 2015

Combination therapy effective in HCV patients with advanced cirrhosis and post-transplant recurrence

Phase 3 results presented today at The International Liver Congress 2015 show that a combination of daclatasvir (DCV), sofosbuvir (SOF) and ribavirin (RBV) for 12 weeks was effective and well tolerated amongst patients with hepatitis C virus (HCV) infection with advanced cirrhosis and post-transplant recurrence.

27 Apr 2015

Humanized mouse model may lead to better anti-cancer therapies

Human tumors grown in mouse models have long been used to test promising anti-cancer therapies. However, when a human tumor is transplanted into a mouse, the mouse immune system must be knocked down so that it doesn't attack the foreign tumor tissue, thus allowing the tumor to grow.

27 Apr 2015

New data supports use DAAs in patients with HCV recurrence following liver transplantation

New data presented today at The International Liver Congress 2015, supports the use of sofosbuvir (SOF)- and daclatasvir (DCV)-based regimens in patients with recurrence of the hepatitis C virus (HCV) following liver transplantation (LT).

25 Apr 2015

AUDs have negative prognostic outcome with higher mortality risks in patients with HCV infection

Results presented today at The International Liver Congress 2015, show that alcohol use disorders (AUD) have a serious, negative prognostic outcome with higher mortality risks in the general population and patients with hepatitis C virus (HCV) infection in particular.

25 Apr 2015

Record number of abstracts submitted to Heart Failure 2015

A record number of abstracts have been submitted to the world's leading heart failure congress, promising more original science than ever before.

25 Apr 2015

Recommended alcoholic hepatitis treatments fail to increase patients' survival

The main drugs used to treat alcoholic hepatitis are not effective at increasing patients' survival, a major study has found. In a trial of over 1,000 patients, prednisolone and pentoxifylline, treatments recommended in international guidelines, did not achieve a statistically significant reduction in mortality after 28 days, 90 days or a year.

24 Apr 2015

Study: Combination therapy shows high SVR rates in HCV patients with decompensated liver disease

Results presented today at The International Liver Congress 2015 show that the use of the fixed-dose combination of ledipasvir/sofosbuvir (LDV/SOF) in combination with ribavirin (RBV) was well tolerated and demonstrated high sustained virologic response rates 12 weeks post treatment (SVR12) in patients with chronic hepatitis C virus (HCV) infection who have decompensated liver disease (cirrhosis) or have undergone liver transplantation.

23 Apr 2015

Transportable MP Airdrive device enhances donor liver viability for transplantation

A new device has demonstrated it has the potential to enhance the viability of donor livers for transplantation. Results revealed today at The International Liver Congress 2015 show that the transportable machine perfusion (MP) Airdrive is able to effectively maintain the quality of livers derived from donation after circulatory death (DCD).

23 Apr 2015

Civacir can effectively prevent HCV recurrence following liver transplants

New data from an ongoing Phase III trial revealed today at The International Liver Congress 2015 show that the use of hepatitis C immune globulin (HCIG, Civacir) can effectively prevent hepatitis C virus (HCV) recurrence in patients following a liver transplant (LT).

23 Apr 2015

UofL receives NIH REACH award to create new ExCITE Hub program

The University of Louisville announced today that a grant from the National Institutes of Health will combine with matching funds from the university to create a new $6.1 million initiative to commercialize discoveries made by UofL researchers.

23 Apr 2015

Stem cell treatment repairs birth defect, provides facial regeneration for people suffering traumatic injury

Researchers have pinpointed a primary cause of a rare skull disorder in infants, and the discovery could help wounded soldiers, car-wreck victims and other patients recover from disfiguring facial injuries.

23 Apr 2015

Survivors of Ebola epidemic donate plasma to tackle disease outbreaks in West Africa

The first donations of plasma, from survivors of the Ebola epidemic in Sierra Leone, have been received by an international research team working to help tackle current and future disease outbreaks in West Africa.

23 Apr 2015

James Shapiro's latest research could soon mark new standard for diabetes treatment

James Shapiro, one of the world's leading experts in emerging treatments of diabetes, can't help but be excited about his latest research. The results he says, could soon mark a new standard for treatment--not only in diabetes, but in several other diseases as well.

22 Apr 2015

UVA research identifies new role of immune system in Rett syndrome

The immune system is designed to protect us from disease. But what if it was malfunctioning? Would it make a disease worse? That appears to be the case with Rett syndrome, a neurodevelopmental disorder, and possibly in other neurological disorders as well, new research from the University of Virginia School of Medicine has found.

22 Apr 2015

Mayo Clinic heart transplant surgeons present findings from three clinical studies at ISHLT 2015

Heart transplant surgeons from Mayo Clinic are presenting findings from three recent clinical studies involving heart transplant patients. The presentations took place during the 2015 International Society of Heart & Lung Transplant in Nice, France, on April 15-18.

21 Apr 2015

New Detroit-designed hospital gown moves from creative concept to patient's bedside

Model G - the new Detroit-designed hospital gown that finally closes the drafty, embarrassing backside - has moved from creative concept to the patient's bedside, with more than 35,000 gowns rolling out this month throughout Henry Ford Health System's hospitals.

17 Apr 2015

HeartWare Ventricular Assist System meets primary endpoint in ENDURANCE clinical trial

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced that data from its first destination therapy clinical trial cohort, ENDURANCE, successfully demonstrated that the trial achieved the primary endpoint.

16 Apr 2015

Early decline in 6MWT distance predicts PAH worsening

Research shows that an early decline in 6-minute walk test distance can predict worsening of disease in patients with pulmonary arterial hypertension.

14 Apr 2015

Researchers cultivate fully functional cardiac tissues from cobweb protein

Genetically engineered fibers of the protein spidroin, which is the construction material for spider webs, has proven to be a perfect substrate for cultivating heart tissue cells, MIPT researchers found. They discuss their findings in an article that has recently come out in the journal PLOS ONE.

13 Apr 2015

Transplant News and Research

Will new hepatitis C treatments strain payers’ budgets? An interview with Dr Chhatwal

Combination therapy effective in HCV patients with advanced cirrhosis and post-transplant recurrence

Humanized mouse model may lead to better anti-cancer therapies

New data supports use DAAs in patients with HCV recurrence following liver transplantation

AUDs have negative prognostic outcome with higher mortality risks in patients with HCV infection

Record number of abstracts submitted to Heart Failure 2015

Recommended alcoholic hepatitis treatments fail to increase patients' survival

Study: Combination therapy shows high SVR rates in HCV patients with decompensated liver disease

Transportable MP Airdrive device enhances donor liver viability for transplantation

Civacir can effectively prevent HCV recurrence following liver transplants

UofL receives NIH REACH award to create new ExCITE Hub program

Stem cell treatment repairs birth defect, provides facial regeneration for people suffering traumatic injury

Survivors of Ebola epidemic donate plasma to tackle disease outbreaks in West Africa

James Shapiro's latest research could soon mark new standard for diabetes treatment

UVA research identifies new role of immune system in Rett syndrome

Mayo Clinic heart transplant surgeons present findings from three clinical studies at ISHLT 2015

New Detroit-designed hospital gown moves from creative concept to patient's bedside

HeartWare Ventricular Assist System meets primary endpoint in ENDURANCE clinical trial

Early decline in 6MWT distance predicts PAH worsening

Researchers cultivate fully functional cardiac tissues from cobweb protein

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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