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Drug combo safely decreases pancreatic cancer growth in mice

A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.

9 Oct 2023

New drug shows promise for epilepsy patients with resistant seizures

In cases where standard therapies fail, a medication called XEN1101 reduces seizure frequency by more than 50% in some patients and sometimes eliminates them altogether, a new study shows.

9 Oct 2023

Study provides evidence for combination therapy as first-line treatment for relapsed ITP

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, conducted a multicenter comprehensive retrospective analysis to assess the effectiveness and safety of primary single-agent and combination therapies in treating adult patients with relapsed immune thrombocytopenia (ITP).

9 Oct 2023

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.

9 Oct 2023

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Intrusive thoughts, involuntary repetition of undesirable gestures and behaviors combined with high anxiety... Obsessive-compulsive disorder (OCD), a disabling condition, affects around 2% of the population, regardless of age.

9 Oct 2023

Precision medicine for gestational diabetes management

Precision markers to predict effective lifestyle and pharmacological interventions to manage Gestational Diabetes Mellitus.

9 Oct 2023

International report paves way for precision diabetes medicine breakthrough

Precision medicine for prevention, diagnosis, treatment, and prognosis for Diabetes.

9 Oct 2023

WHO experts recommend the use of Takeda's dengue vaccine QDENGA

Takeda today announced that the World Health Organization’s (WHO) Strategic Advisory Group of Experts (SAGE) on Immunization shared recommendations for use of QDENGA® (Dengue Tetravalent Vaccine [Live, Attenuated]) (TAK-003).

9 Oct 2023

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Using antigenic cartography, researchers analyzed cross-reactivity patterns of SARS-CoV-2 variants and the effect of spike-protein changes on post-infection and vaccination immune responses. The study illuminated unique neutralization profiles and underscored the evolving defense mechanisms with repeated immunizations.

8 Oct 2023

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

Recent study assesses NVX-CoV2373 vaccine's effectiveness against Omicron variant. Findings show decreased efficacy over four months, but stable protection against symptomatic COVID-19.

8 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

Gut health and leukemia: Exploring the crucial connection between diet and microbiota changes

Gut microbiota's role in leukemia treatment responses is explored, with evidence suggesting diet and prebiotics may help manage microbiota alterations in patients. Diet during pregnancy, breastfeeding, and gut microbiota composition all intersect, potentially influencing leukemia risks and treatment outcomes.

8 Oct 2023

Nirmatrelvir and ritonavir combo cuts COVID-19 risks for high-vulnerability groups

Nirmatrelvir and ritonavir treatment significantly reduces the risk of hospitalization and death from COVID-19 in high-risk individuals, according to a recent JAMA Network Open study. However, the treatment's efficacy varied based on the degree of vulnerability, emphasizing tailored approaches for different risk groups.

8 Oct 2023

Non-invasive eye exam could be a valuable tool for early detection of cerebral small vessel disease

A research team led by the Keck School of Medicine of USC has discovered that a non-invasive eye exam may be a possible tool for screening Black Americans and other people from underdiagnosed and high-risk populations for cerebral small vessel disease, a major contributor to cognitive impairment and dementia.

6 Oct 2023

What is the burnout rate among US physicians over the past 5 years?

Physician burnout is a major issue affecting the quality and availability of healthcare in the US. The rising rate of this problem spurred a recent study aimed at identifying its roots.

6 Oct 2023

A telehealth model to support remote diabetes self-care

Researchers develop and test the effectiveness of a Virtual Diabetes Specialty Clinic (VDiSC), a virtual model facilitating comprehensive diabetes care remotely.

6 Oct 2023

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Researchers introduced and characterized a novel platform based on monoclonal antibodies (mAbs).

6 Oct 2023

Why are most Americans skipping the COVID-19 booster?

A study in the journal Vaccine reveals that misinformation and concerns about side effects are leading reasons why over 80% of eligible Americans have skipped the SARS-CoV-2 vaccine booster. The research underscores the need for more public education about the vaccine's benefits in combating severe COVID-19 infections.

5 Oct 2023

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alzheimer's disease.

5 Oct 2023

New technology helps pregnant women with type 1 diabetes to better manage blood sugar levels

For pregnant women with type 1 diabetes, a technology giving insulin doses, as informed by a smartphone algorithm, helps them better manage their blood sugars compared with traditional insulin pumps or multiple daily injections, according to a new randomized trial published in The New England Journal of Medicine (NEJM) and presented at the European Association for the Study of Diabetes (EASD) meeting in Hamburg (2-6 October).

5 Oct 2023

Efficacy News and Research

Drug combo safely decreases pancreatic cancer growth in mice

New drug shows promise for epilepsy patients with resistant seizures

Study provides evidence for combination therapy as first-line treatment for relapsed ITP

Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

Psychedelics may increase neuroplasticity by promoting the remodeling of synaptic connections

Precision medicine for gestational diabetes management

International report paves way for precision diabetes medicine breakthrough

WHO experts recommend the use of Takeda's dengue vaccine QDENGA

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Novavax vaccine shows resilient defense against symptomatic COVID-19 despite Omicron challenge

Researchers explore immunomodulating targets for improving glioblastoma therapies

Gut health and leukemia: Exploring the crucial connection between diet and microbiota changes

Nirmatrelvir and ritonavir combo cuts COVID-19 risks for high-vulnerability groups

Non-invasive eye exam could be a valuable tool for early detection of cerebral small vessel disease

What is the burnout rate among US physicians over the past 5 years?

A telehealth model to support remote diabetes self-care

Breakthrough antibody therapy targets Alzheimer's risk gene, offers hope for effective treatment

Why are most Americans skipping the COVID-19 booster?

New antibody shows promise in reducing tau proteins associated with Alzheimer's disease

New technology helps pregnant women with type 1 diabetes to better manage blood sugar levels

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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