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Highly sensitive DNA test identifies neuroborreliosis in horses

A Rutgers scientist aiming to help heal a sick horse created an ultra-sensitive DNA test that could have applications for difficult-to-detect illnesses in humans such as Lyme disease.

18 Aug 2022

Researchers create novel mouse model for mapping protein communication between organs

Our many different organ systems are in constant communication with each other. During exercise, for example, muscles send out signals to fat and liver tissue to release their energy sources.

17 Aug 2022

Genomic surveillance highlights the challenges posed by "shapeshifting" strains

A pioneering genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumonia and meningitis, and the vaccines designed to protect against the most dominant types. A strain called GPSC10 was found to be a particular threat, due to its increased virulence, ability to transform its structure to evade vaccines and its resistance to several common antibiotics.

17 Aug 2022

How useful is PCR for diagnosing monkeypox?

Researchers explore the reliability of PCR for monkeypox diagnosis.

16 Aug 2022

SARS-CoV-2 evolution within hosts and vaccination effects

A new study explores the mutational profiles within individuals infected with SARS-CoV-2.

16 Aug 2022

Mechanism of vaccinia virus assembly in infected-cells

In a new study, researchers explored the driving factors of the vaccinia virus assembly across infected cells.

16 Aug 2022

Computational pipeline for the early identification of emerging SARS-CoV-2 variants

Researchers developed a computational pipeline for the early identification of emerging SARS-CoV-2 variants of interest by analyzing SARS-CoV-2 genome data and allocating risk scores on the basis of functional and epidemiological parameters.

16 Aug 2022

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

Verogen, Inc. and Gene by Gene today announced a partnership to accelerate the adoption of forensic investigative genetic genealogy.

From Verogen, Inc. 16 Aug 2022

Three genetic mutations seen in individuals with KCNMA1-linked channelopathy successfully mirrored in mice

Three genetic alterations associated with a rare seizure and a movement disorder primarily found in children were successfully mirrored in mice and their symptoms treated, in a new study from a University of Maryland School of Medicine researcher, Andrea Meredith, PhD, Professor of Physiology and her collaborators.

15 Aug 2022

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Researchers compare the length spectra of sperm mitochondrial DNA deletions in two seasons with varied air pollution levels.

14 Aug 2022

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Why does the risk of heart disease go up as we age? Known risk factors such as hypertension or high cholesterol don't explain all cases.

12 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

What is the genomic diversity of SARS-CoV-2 infections in households?

In a new study, researchers assessed the genomic diversity of SARS-CoV-2 in households.

12 Aug 2022

Novel zoonotic Langya virus identified in China

Scientists discuss their discovery of the novel Langya henipavirus in eastern China.

11 Aug 2022

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022

Recombination most often occurs on the COVID-19 phylogenetic tree in the form of 'long branches'

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to attach to and infect host cells.

11 Aug 2022

Transposable element controls the immune system to favor host survival during virus infection

Researchers from UNSW Sydney have discovered that a particular transposable element, or jumping gene, in the genome has a profound effect on the immune response to virus infection.

11 Aug 2022

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

11 Aug 2022

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression.

11 Aug 2022

Scientists discover new target for treatment of premature aging disorders

A stretch of DNA that hops around the human genome plays a role in premature aging disorders, scientists at the Salk Institute and King Abdullah University of Science and Technology in Saudi Arabia have discovered.

10 Aug 2022

Genome News and Research

Highly sensitive DNA test identifies neuroborreliosis in horses

Researchers create novel mouse model for mapping protein communication between organs

Genomic surveillance highlights the challenges posed by "shapeshifting" strains

How useful is PCR for diagnosing monkeypox?

SARS-CoV-2 evolution within hosts and vaccination effects

Mechanism of vaccinia virus assembly in infected-cells

Computational pipeline for the early identification of emerging SARS-CoV-2 variants

Verogen and Gene by Gene Form Groundbreaking Partnership to Accelerate Adoption of Forensic Investigative Genetic Genealogy

Three genetic mutations seen in individuals with KCNMA1-linked channelopathy successfully mirrored in mice

Men exposed to industrial air pollution exhibit sperm mitochondrial DNA deletions

Older heart muscle cells accumulate new genetic mutations -; while losing the ability to repair them

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

What is the genomic diversity of SARS-CoV-2 infections in households?

Novel zoonotic Langya virus identified in China

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Recombination most often occurs on the COVID-19 phylogenetic tree in the form of 'long branches'

Transposable element controls the immune system to favor host survival during virus infection

Nearly three-quarters of all stem cell lines are affected by DNA damage, say researchers

Study defines how the circadian clock influences cell growth, metabolism and tumor progression

Scientists discover new target for treatment of premature aging disorders

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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