Pharmaceuticals News and Research

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$Sostdc1 gene may play vital role in fracture healing process$

Sostdc1 gene may play vital role in fracture healing process

New identification of a gene involved in the fracture healing process could lead to the development of new therapeutic treatments for difficult-to-heal injuries.

2 Jun 2016

New technique could help reduce chances of drug failure during later stages of clinical trials

An approach that could reduce the chances of drugs failing during the later stages of clinical trials has been demonstrated by a collaboration between the University of Cambridge and pharmaceutical company GlaxoSmithKline.

2 Jun 2016

AbbVie, Sanofi and Novo Nordisk listed among top 10 companies in 2016 UK Pharma RepTrak rankings

AbbVie, Sanofi and Novo Nordisk top the RepTrak® ranking of the most reputable pharmaceutical companies in the UK, Reputation Institute announced today, based on more than 1,600 ratings collected in the first quarter of 2016 from members of the UK general public.

1 Jun 2016

Overcoming barriers in autism research: an interview with Gahan Pandina

There are currently no medications which address the core symptoms of ASD, and a significant barrier to their development is that researchers have historically lacked effective methods for measuring clinical outcomes.

30 May 2016

Pharmacist suggests education as foremost strategy to control opioid abuse

Technologies that make it harder for people to abuse opioids - like doctoring pills so that they produce unpleasant side effects if broken, crushed or injected -- likely will have limited effectiveness in stemming the global epidemic of opioid abuse, according to Adam Kaye, a professor of pharmacy at University of the Pacific.

28 May 2016

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Deep learning, frequently referred to as artificial intelligence, a branch of machine learning utilizing multiple layers of neurons to model high-level abstractions in data, has outperformed humans in tasks including image, text and voice recognition, autonomous driving and others, and is now being applied to drug discovery and biomarker development.

28 May 2016

Organic chemists succeed in synthesizing 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity

The pyran ring is present in so many useful compounds, such as pharmaceuticals (antibiotics, anti-infectives, cardiovascular agents, neurological modulators, anti-allergic, anti-asthmatic, anti-inflammatory agents, reproductive and genitourinary agents, growth promoters and antidiabetic agents), veterinary products, agrochemicals, toxins, polymers and additives, photosensitizers and photoinitiators, surfactants, food products, dyes and pigments.

28 May 2016

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System.

27 May 2016

New understanding of neurotransmitter transporter mechanism gives hope for treating depression, addicition

When nerve cells have to communicate with each other in our brains, it involves release of small signal molecules, the so-called neurotransmitters, which act as chemical messengers in specific points of contact between nerve cells, called synapses.

27 May 2016

Diabetes societies endorse 'metabolic surgery'

An "unprecedented" number of societies have endorsed guidelines recommending metabolic surgery for patients with diabetes - and not just for patients with severe obesity.

27 May 2016

Study reveals brain mechanism involved in switching between habitual behavior and decision-making

Not all habits are bad. Some are even necessary. It's a good thing, for example, that we can find our way home on "autopilot" or wash our hands without having to ponder every step. But inability to switch from acting habitually to acting in a deliberate way can underlie addiction and obsessive compulsive disorders.

27 May 2016

Study reveals males and females exhibit different stress responses

How does stress - which, among other things, causes our bodies to divert resources from non-essential functions - affect the basic exchange of materials that underlies our everyday life? Weizmann Institute of Science researchers investigated this question by looking at a receptor in the brains of mice, and they came up with a surprising answer.

27 May 2016

New tablet fabrication method can make personalized medicine cheaper, easier

A team of researchers from the National University of Singapore have found a way to make personalized medicine cheaper and easier.

26 May 2016

Research sheds new light on biological processes underlying neurodegeneration in AD

Progranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal theme shared across several common neurodegenerative diseases.

26 May 2016

$ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients$

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

Data from the 48-week ART trial, presented today at the Digestive Disease Week meeting, showed that remission and response rates were 37.2% and 53.2% respectively at week 12, in patients with moderate-to-severe, steroid-dependent active ulcerative colitis (UC) with insufficient response or intolerance to immunosuppressants and / or biologics when treated with between five and eight sessions with Adacolumn.

26 May 2016

TSRI scientists discover new method for harnessing venoms for therapeutic use

There are lessons to be learned from venoms. Scorpions, snakes, snails, frogs and other creatures are thought to produce tens or even hundreds of millions of distinct venoms. These venoms have been honed to strike specific targets in the body.

26 May 2016

Automated Liquid Handling in Pharmaceutical Research

In this interview, News Medical talks to Dr. Alfred Chappell of Ionis Pharmaceuticals about automated liquid handling in pharmaceutical research.

From Beckman Coulter Life Sciences - Automation and Genomics 26 May 2016

SBP scientists discover new regulator of immune responses

Research led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a new regulator of immune responses. The study, published recently in Immunity, sheds new light on why T cells fail to clear chronic infections and eliminate tumors.

26 May 2016

Researchers discover new potential treatment target for liver cancer

Researchers at the University of Eastern Finland and Eberhard Karls Universität Tübingen have discovered a new molecular mechanism that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer.

24 May 2016

Researchers genetically modify microalgae to form complex molecules

Researchers from Copenhagen Plant Science Centre at University of Copenhagen have succeeded in manipulating a strain of microalgae to form complex molecules to an unprecedented extent.

23 May 2016

Pharmaceuticals News and Research

Sostdc1 gene may play vital role in fracture healing process

New technique could help reduce chances of drug failure during later stages of clinical trials

AbbVie, Sanofi and Novo Nordisk listed among top 10 companies in 2016 UK Pharma RepTrak rankings

Overcoming barriers in autism research: an interview with Gahan Pandina

Pharmacist suggests education as foremost strategy to control opioid abuse

Applying deep neural networks to predict pharmacologic properties of drugs and drug repurposing

Organic chemists succeed in synthesizing 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity

NR supplements can reduce diabetes-related complications in mice

New understanding of neurotransmitter transporter mechanism gives hope for treating depression, addicition

Diabetes societies endorse 'metabolic surgery'

Study reveals brain mechanism involved in switching between habitual behavior and decision-making

Study reveals males and females exhibit different stress responses

New tablet fabrication method can make personalized medicine cheaper, easier

Research sheds new light on biological processes underlying neurodegeneration in AD

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

TSRI scientists discover new method for harnessing venoms for therapeutic use

Automated Liquid Handling in Pharmaceutical Research

SBP scientists discover new regulator of immune responses

Researchers discover new potential treatment target for liver cancer

Researchers genetically modify microalgae to form complex molecules

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