Protein C News and Research

RSS

JAMIA highlights several perspectives, five research articles on translational bioinformatics

With the summer edition of JAMIA--currently online at www.JAMIA.org--AMIA's peer-reviewed journal on informatics in biomedicine and health opens the door to translational science, highlighting several perspectives and five research articles on translational bioinformatics (TBI), and suggesting that future publications in greater volume will help keep JAMIA readers abreast of new developments and applications of translational bioinformatics, just as more hospital and academic health centers are embracing molecular measurements for diagnosis and planning therapies.

4 Aug 2011

Innovative delivery systems and methods to treat breast cancer

In their lifetime, women have more than a 12 percent risk of being diagnosed with breast cancer. 1 This week, research on novel approaches to breast cancer treatment is being presented at the Era of Hope (EOH) conference, a scientific meeting hosted by the Department of Defense Breast Cancer Research Program (BCRP).

4 Aug 2011

Accurate, non-invasive and inexpensive test can detect Alzheimer's

Scientists from Durin Technologies, Inc., and the University of Medicine and Dentistry of New Jersey (UMDNJ)-School of Osteopathic Medicine have developed a blood test that uses human protein microarrays to detect the presence of specific antibodies in the blood that can be used to diagnose Alzheimer's disease with unprecedented accuracy.

4 Aug 2011

Acceleron, Celgene enter development collaboration for ACE-536 protein therapeutic to treat anemia

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, and Celgene Corporation today announced that the companies have entered into a joint development and commercialization agreement for ACE-536 for the treatment of anemia.

3 Aug 2011

Researchers discover biological mechanism behind sarcopenia

Researchers at Columbia University Medical Center have discovered the biological mechanism behind age-related loss of muscle strength and identified a drug that may help reverse this process.

3 Aug 2011

New approach reduces cyanogen, enhances nutritional value in root crop

Researchers working at The Donald Danforth Plant Science Center have made an another advancement in their efforts to improve the root crop cassava which is a major source of calories to 700 million people worldwide, primarily living in the developing world.

3 Aug 2011

Prolonged estrogen deprivation reduces ability to prevent strokes

Prolonged estrogen deprivation in aging rats dramatically reduces the number of brain receptors for the hormone as well as its ability to prevent strokes, researchers report.

3 Aug 2011

New approach to overcome complexities of developing more effective drugs for treating diseases

Pharmaceutical scientists typically face a meager five percent success rate for anti-cancer drugs in clinical trials. To help improve this success rate, Japanese scientists, led by Dr. Tetsuya Terasaki, one of the top pharmaceutical scientists focused on drug transporters, have developed a new approach designed to overcome complexities of developing new, more effective drugs to treat diseases, including cancer.

3 Aug 2011

Combination molecules with BRAF inhibitors may help overcome drug resistance in melanoma patients

About 50 to 60 percent of patients with melanoma have a mutation in the BRAF gene that drives the growth of their cancer. Most of these patients respond well to two novel agents being studied in clinical trials that inhibit the gene, with remarkable responses that are, unfortunately, almost always limited in duration.

3 Aug 2011

Insight into how brain organizes during development

Scientists at the Allen Institute for Brain Science have taken an important step in identifying how the brain organizes itself during development. The findings, published in the Journal of Comparative Neurology today, describe - in more detail than ever before - the consequences of the loss of a key molecule involved in establishing proper brain architecture during brain development.

3 Aug 2011

Mood-related brain protein linked to sadness during cigarette withdrawal

Heavy smokers may experience sadness after quitting because early withdrawal leads to an increase in the mood-related brain protein monoamine oxidase A (MAO-A), a new study by the Centre for Addiction and Mental Health (CAMH) has shown. This finding, which was published in the Archives of General Psychiatry, may also explain why heavy smokers are at high risk for clinical depression.

3 Aug 2011

VIB researchers develop mouse model for Charcot-Marie-Tooth neuropathy

VIB researchers have developed a mouse model for Charcot-Marie-Tooth (CMT) neuropathy, a hereditary disease of the peripheral nervous system.

3 Aug 2011

Novel therapy reduces elevated blood levels of toxic protein in women with preeclampsia

A novel therapy that reduces elevated blood levels of a potentially toxic protein in women with preeclampsia, a dangerous complication of pregnancy, may someday address the therapeutic dilemma posed by the condition - balancing life-threatening risks to the mother with the dangers that early delivery poses to an immature fetus.

3 Aug 2011

BARDA awards contracts for development of drugs for radiation injury to the GI tract

The first two contracts for advanced development of drugs to treat gastrointestinal (GI) tract injuries associated with acute radiation syndrome were awarded today by the U.S. Department of Health and Human Services' Biomedical Advanced Research and Development Authority (BARDA).

2 Aug 2011

New cold electron source could improve quality and speed of nanoimaging for drug development

A new source of very cold electrons will improve the quality and speed of nanoimaging for drug and materials development to a trillionth of a second.

2 Aug 2011

Scientists produce first systematic network map of plant protein interactions

An international consortium of scientists has produced the first systematic network map of interactions that occur between proteins in the plant Arabidopsis thaliana.

2 Aug 2011

Taxoxifen combined with dasatinib reverses chemo-resistance in breast cancer cells

Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests.

2 Aug 2011

Scientists design octapeptides to fight drug resistant ovarian cancer cells

Italian and German scientists have designed peptides to target the protein-protein interface of a key enzyme in DNA synthesis crucial for cancer growth. The peptides act by a novel inhibitory mechanism and curb cancer cell growth in drug resistant ovarian cancer cells.

2 Aug 2011

Nature Biotechnology publishes BGI, GT Life Sciences' study on CHO K1 genome

BGI, the world's largest genomics organization, and GT Life Sciences, Inc., a privately held biotechnology company that utilizes a proven metabolic modeling and experimental platform to drive the discovery and design of new products and processes for the life sciences field, announced today that their collaborative study on the genomic sequence of the Chinese hamster ovary (CHO) K1 cell line was published July 31, 2011 online in Nature Biotechnology.

1 Aug 2011

Researchers identify new plasma membrane sculpting protein

The research group of Professor Pekka Lappalainen at the Institute of Biotechnology, University of Helsinki, has identified a previously unknown mechanism which modifies the structure of plasma membranes in intestinal epithelial cells.

1 Aug 2011

Protein C News and Research

JAMIA highlights several perspectives, five research articles on translational bioinformatics

Innovative delivery systems and methods to treat breast cancer

Accurate, non-invasive and inexpensive test can detect Alzheimer's

Acceleron, Celgene enter development collaboration for ACE-536 protein therapeutic to treat anemia

Researchers discover biological mechanism behind sarcopenia

New approach reduces cyanogen, enhances nutritional value in root crop

Prolonged estrogen deprivation reduces ability to prevent strokes

New approach to overcome complexities of developing more effective drugs for treating diseases

Combination molecules with BRAF inhibitors may help overcome drug resistance in melanoma patients

Insight into how brain organizes during development

Mood-related brain protein linked to sadness during cigarette withdrawal

VIB researchers develop mouse model for Charcot-Marie-Tooth neuropathy

Novel therapy reduces elevated blood levels of toxic protein in women with preeclampsia

BARDA awards contracts for development of drugs for radiation injury to the GI tract

New cold electron source could improve quality and speed of nanoimaging for drug development

Scientists produce first systematic network map of plant protein interactions

Taxoxifen combined with dasatinib reverses chemo-resistance in breast cancer cells

Scientists design octapeptides to fight drug resistant ovarian cancer cells

Nature Biotechnology publishes BGI, GT Life Sciences' study on CHO K1 genome

Researchers identify new plasma membrane sculpting protein

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News