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ORACLE test enhances prediction of lung cancer outcomes

A new test, developed by researchers from UCL Cancer Institute and the Francis Crick Institute, can better predict lung cancer survival at the point of diagnosis, which could inform treatment decisions and potentially reduce the risk of the cancer returning or spreading.

13 Jan 2025

Scientists uncover genetic secrets of Staphylococcus aureus survival in humans

The most detailed study to date on the mechanisms by which a common type of bacterium, Staphylococcus aureus, adapts to living on the human body could help improve the prevention, diagnosis, and treatment of certain infections.

13 Jan 2025

Genetic risk for dementia shapes parenting and family planning choices

Living in a family where there is genetic risk for dementia significantly affects choices about having children and how to parent, finds a new study led by UCL researchers.

13 Jan 2025

By 2060, 1 million U.S. adults are projected to develop dementia annually

The lifetime risk of dementia is 42%, with significant variations by race and sex, underscoring the importance of public health strategies for prevention.

13 Jan 2025

Gut bacterium associated with reduced dietary sugar intake

This study links Ffar4, gut microbiota, and sugar preference, highlighting potential strategies for managing diabetes and obesity through dietary interventions.

13 Jan 2025

Plant chemical discovered to prevent biofilm formation

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

10 Jan 2025

New study highlights gender differences in diagnosing heart condition

Women may be missing a diagnosis of a potentially deadly heart condition due to guidelines that don't account for natural differences in sex and body size, according to a new study led by UCL (University College London) researchers.

10 Jan 2025

Brain maturation delays linked to unhealthy eating behaviors in youth

More than half of 23-year-olds in a European study show restrictive, emotional or uncontrolled eating behaviors, according to new research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London.

10 Jan 2025

Most disease-causing mutations that swap amino acids do so by making proteins less stable

Research shows 60% of missense mutations destabilize proteins, linking protein folding to genetic diseases, including cataracts and neurological disorders.

10 Jan 2025

Dairy products linked to lower colorectal cancer risk, thanks to calcium

This study reveals strong links between calcium intake and reduced colorectal cancer risk, highlighting dietary factors influencing cancer incidence in women.

10 Jan 2025

Health care AI, intended to save money, turns out to require a lot of expensive humans

Preparing cancer patients for difficult decisions is an oncologist's job. They don't always remember to do it, however.

10 Jan 2025

Researchers identify shared genes driving cancer spread

Cancer metastasis-the spread of cancer to other organs-is the leading cause of death among cancer patients. Researchers have now uncovered a "genetic signature" of 177 genes shared across multiple cancer types that drives this deadly process.

10 Jan 2025

Developing and refining muscle atrophy models for drug discovery

With the intensification of global population aging, muscle atrophy, characterized by the loss of muscle mass and function, has become an important health issue affecting the elderly. Researchers have widely used various animal and cellular models to gain a deeper understanding of the pathophysiological mechanisms of muscle atrophy and develop effective treatment strategies.

9 Jan 2025

A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025