Proliferation News and Research

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Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.

5 Sep 2013

Boosting Your Brain Power With Sleep

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4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Research findings could lead to new therapeutic approaches for liver cancer

Liver cancer (Hepatocellular Carcinoma, HCC) usually arises as the result of a chronic, inflammatory liver disease. The most common causes here are excessive alcohol consumption as well as a high-fat diet and also chronic infection with the hepatitis viruses B and C. In the course of the inflammatory process, the liver cells (hepatocytes) die more frequently due to programmed cell death.

30 Aug 2013

Research suggests clingy blood platelets may offer hope for people with rheumatoid arthritis

No one likes clingy people, but "clingy" blood platelets may offer hope for millions of people with rheumatoid arthritis. According to new research findings published in The Journal of Leukocyte Biology, a sub population of immune cells (lymphocytes) known to play a significant role in rheumatoid arthritis has platelets attached to their surface.

30 Aug 2013

BTNL2 gene mutation that impacts immune function increases risk of prostate cancer

A team of researchers led by Janet Stanford, Ph.D., of Fred Hutchinson Cancer Research Center has discovered that mutations in the gene BTNL2, which encodes a protein involved in regulating T-cell proliferation and cytokine production - both of which impact immune function - increase the risk of developing prostate cancer.

30 Aug 2013

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine.

29 Aug 2013

Research links increased breast cancer risk to more alcohol drinking before motherhood

Here's a sobering fact for millions of young women heading back to school: The more alcohol they drink before motherhood, the greater their risk of future breast cancer.

29 Aug 2013

MFDCs have advantages over adult skin cells, including proliferation and differentiation

Multipotent fetal dermal cells (MFDCs) may be an ideal source for cell therapy for repairing damaged tissues and organs. Their performance is superior to that of adult dermal cells, said a research team in Italy that developed a cell isolation technique for MFDCs and subsequently published a study that appears as an early e-publication for the journal Cell Transplantation.

23 Aug 2013

MC1R mutation responsible for red hair phenotype also promotes cancer-causing pathway

A person's skin pigment, which determines hair color and skin tone, is influenced by the melanocortin-1 (MC1R) gene receptor. For the population's one to two percent of redheads, a mutation in MC1R accounts for their red hair color and typical light skin.

23 Aug 2013

Use of psychotherapy on a clear decline in US

Psychotherapy has issues. Evidence shows that some psychosocial treatments work well for common mental health problems such as anxiety and depression and that consumers often prefer them to medication.

22 Aug 2013

Radiation Oncologist receives Young Investigator Award from PCF

Jefferson Radiation Oncologist, Nicole Simone, M.D., was recently awarded one of 21 Young Investigator Awards from the Prostate Cancer Foundation (PCF).

21 Aug 2013

Two proteins identified as prime suspects in proliferation of breast cancer

Two proteins have been identified as prime suspects in the proliferation of breast cancer in a study by an international consortium of researchers from Rice University, the University of North Texas, Denton (UNT); the University of California, San Diego (UCSD); and the Hebrew University of Jerusalem.

21 Aug 2013

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for Perinatal Research and pediatric surgeon for the Department of Pediatric Surgery at Nationwide Children's Hospital, and her team have found that this may just be the case with HB-EGF, or heparin-binding EGF-like growth factor.

21 Aug 2013

Chinese herbal medicine JSK protects against injury caused by damage to spinal cord blood vessels

A new study published in Restorative Neurology and Neuroscience demonstrates that Chinese herbal medicine Ji-Sui-Kang (JSK), given systemically for three weeks after injury in rats, improved locomotor function, reduced tissue damage, and preserved the structure of neural cells compared to control rats.

20 Aug 2013

Dermatology researcher receives NIH grant to investigate role of nervous system in psoriasis

Dermatology researcher Nicole Ward, PhD, has earned her third National Institutes of Health grant in a year - including two that scored in the first percentile. With this most recent award, an R21, she will investigate the role the nervous system plays in psoriasis - an inflammatory autoimmune disease characterized by raised areas of red, scaly, itchy and sometimes painful patches of skin.

17 Aug 2013

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Osteoarthritis is an extremely common condition affecting about 8 million people in the UK. The elderly are particularly susceptible, with up to 45% of people over 65 years, having the disease.

14 Aug 2013

Neural stem cells transplantation in tumor-bearing rats can hinder tumor cell growth

Neural stem cells transplanted into tumor-bearing rats can hinder tumor cell growth and prolife-ration; however, the mechanism remains unclear.

14 Aug 2013

Researchers discover why early pregnancy reduces breast cancer

An international scientific collaborative led by the Harvard Stem Cell Institute's Kornelia Polyak, MD, PhD, has discovered why women who give birth in their early twenties are less likely to eventually develop breast cancer than women who don't, triggering a search for a way to confer this protective state on all women.

13 Aug 2013

Proliferation News and Research

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Boosting Your Brain Power With Sleep

Study: Changes in expression of various isoforms might play role in cancer development

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Research findings could lead to new therapeutic approaches for liver cancer

Research suggests clingy blood platelets may offer hope for people with rheumatoid arthritis

BTNL2 gene mutation that impacts immune function increases risk of prostate cancer

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Research links increased breast cancer risk to more alcohol drinking before motherhood

MFDCs have advantages over adult skin cells, including proliferation and differentiation

MC1R mutation responsible for red hair phenotype also promotes cancer-causing pathway

Use of psychotherapy on a clear decline in US

Radiation Oncologist receives Young Investigator Award from PCF

Two proteins identified as prime suspects in proliferation of breast cancer

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

Chinese herbal medicine JSK protects against injury caused by damage to spinal cord blood vessels

Dermatology researcher receives NIH grant to investigate role of nervous system in psoriasis

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Neural stem cells transplantation in tumor-bearing rats can hinder tumor cell growth

Researchers discover why early pregnancy reduces breast cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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