immunity News and Research

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High risk of COVID-19 breakthrough infections among vaccinated individuals with cancer

Researchers examined the risk of breakthrough COVID-19 infections, hospitalizations, and mortality among COVID-19-vaccinated cancer patients.

13 Apr 2022

SARS-CoV-2 spreads extensively in households, with children being an important source of spread

A study released today indicates that SARS-CoV-2 (COVID-19) spreads extensively in households, with children being a significant source of that spread. Approximately 50% of household members were infected from the first-infected individual during the study period.

13 Apr 2022

Zika virus can mutate to become more infective and dangerous, finds study

LA JOLLA, CA - Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective - and potentially break through pre-existing immunity.

13 Apr 2022

Research shows effectiveness of a 3rd mRNA COVID-19 vaccine dose

A recent study assessed the efficacy of the second and third doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) messenger ribonucleic acid (mRNA) vaccines against the SARS-CoV-2 Omicron and Delta variants in outpatient settings.

13 Apr 2022

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers characterized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S)-specific cluster of differentiation 8 (CD8+) T cell responses.

12 Apr 2022

Antibody response following Omicron BA.2 infection is lower than BA.1

In a recent report posted to the medRxiv* preprint server, researchers determined immune responses generated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineage infections in prior virus-infected and naïve subjects.

12 Apr 2022

Severe COVID-19 extremely rare among children

A new Journal of Infection study describes the findings in children who contracted SARS-CoV-2 infection in England.

12 Apr 2022

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

CoVac-1, a new vaccine against SARS-CoV-2, induced T-cell immune responses in 93 percent of patients with B-cell deficiencies, including many patients with leukemia and lymphoma, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

12 Apr 2022

Parallel approach to vaccine trials can lead to faster and more accurate assessment

Some of Rutgers' top health researchers are calling for a change in our approach to developing COVID-19 vaccines, and vaccines to fight future pandemics, to incorporate both conventional and challenge trails.

12 Apr 2022

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

In a new study, researchers quantified the serological responses following the third dose of mRNA-based COVID-19 vaccines in patients with hematological malignancies.

12 Apr 2022

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications are uncommon, yet treatable for children and young adults after COVID-19 disease or SARS-CoV-2 infection, according to a new scientific statement from the American Heart Association that details what has been learned about how to treat, manage and even prevent cardiovascular complications from the SARS-CoV-2 virus in youth.

12 Apr 2022

Early COVID-19 reinfections possible within 60 days of initial infection

Researchers reported that COVID-19 reinfections could occur within 60 days of the initial infection.

12 Apr 2022

Experimental tool can precisely pick out interactions between immune cell and target antigen

The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells' ability to recognize harmful microbes is critical to successfully fighting off infection.

12 Apr 2022

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Researchers evaluated the immunogenicity of Pfizer’s BNT162b2 and Moderna’s mRNA-1273 vaccines offered as the fourth dose against SARS-CoV-2.

12 Apr 2022

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

Study finds molecular features responsible for the development of metastatic breast cancer

Susana Garcia-Recio, PhD, a research associate in the lab of Charles M. Perou, PhD, at UNC Lineberger Comprehensive Cancer Center, will present findings that identified molecular features responsible for the development and progression of metastatic breast cancer at the 2022 American Association for Cancer Research annual meeting. (Presentation: Abstract LB176/4, Tuesday, April 12, 3:20 p.m. ET, Room 217-219, Ernest N. Morial Convention Center in New Orleans.)

11 Apr 2022

Chromatin accessibility as an early marker of severe COVID-19

A new study explores the possible use of chromatin remodeling in predicting a severe clinical trajectory for COVID-19.

11 Apr 2022

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

Researchers tested whether a subunit vaccine could generate mucosal immunity in mice and prevent SARS-CoV-2 infection and related pathology.

11 Apr 2022

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

A new study illustrated that inadequate population immunity exacerbated the SARS-CoV-2 Omicron BA.2 sublineage outbreak in Hong Kong.

11 Apr 2022

The human antibody response to the SARS-CoV-2 spike protein N-terminal domain in a group of previously infected individuals

Researchers evaluated the human antibody response to the NTD of the S protein by investigating a group of individuals who had previously been infected with SARS-CoV-2 or who had received an mRNA vaccine.

11 Apr 2022

immunity News and Research

High risk of COVID-19 breakthrough infections among vaccinated individuals with cancer

SARS-CoV-2 spreads extensively in households, with children being an important source of spread

Zika virus can mutate to become more infective and dangerous, finds study

Research shows effectiveness of a 3rd mRNA COVID-19 vaccine dose

mRNA vaccines induce CD8+ T cells that may reduce COVID-19 severity

Antibody response following Omicron BA.2 infection is lower than BA.1

Severe COVID-19 extremely rare among children

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

Parallel approach to vaccine trials can lead to faster and more accurate assessment

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Early COVID-19 reinfections possible within 60 days of initial infection

Experimental tool can precisely pick out interactions between immune cell and target antigen

Safety, reactogenicity, and immunogenicity of the BNT and half-m1273 mRNA COVID-19 vaccines given as a fourth dose booster

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

Study finds molecular features responsible for the development of metastatic breast cancer

Chromatin accessibility as an early marker of severe COVID-19

Prime-pull immunization of mice with novel subunit vaccine elicits mucosal immunity to prevent severe SARS CoV-2 infection

SARS-CoV-2 Omicron BA.2 sublineage outbreak aggravated by low population immunity in Hong Kong

The human antibody response to the SARS-CoV-2 spike protein N-terminal domain in a group of previously infected individuals

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