Central Nervous System News and Research

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New insights into understanding of neurological disorders

Increasingly sophisticated imaging tools and techniques are emerging that make it possible to probe the organization and activity of the brain at the cellular and molecular level, leading to a better understanding of the complex networks that link brain structure and function.

8 Jun 2011

Survivors of childhood cancer at increased risk of developing subsequent primary neoplasms

In a study that included nearly 18,000 children who had cancer, with follow-up of about 25 years, the greatest excess risk associated with a subsequent primary neoplasm (a new tumor) at older than age 40 years was for digestive and genitourinary neoplasms (related to the genital or urinary tract organs), according to a study in the June 8 issue of JAMA, a theme issue on cancer.

7 Jun 2011

Genentech's Avastin, chemotherapy Phase III combination study data on ovarian cancer presented at ASCO

Genentech, a member of the Roche Group, today announced results from OCEANS, a Phase III study evaluating Avastin (bevacizumab) in combination with chemotherapy followed by the continued use of Avastin alone in women with previously treated (recurrent) platinum-sensitive ovarian cancer.

6 Jun 2011

Anti-ghrelin vaccine decreases food intake and increases calorie burning in mice

A new therapeutic vaccine to treat obesity by suppressing the appetite-stimulating hormone ghrelin decreases food intake and increases calorie burning in mice, a new study finds. The results will be presented Sunday at The Endocrine Society's 93rd Annual Meeting in Boston.

6 Jun 2011

DFG to form new collaborative research centers as of 1 July 2011

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) will establish 21 new Collaborative Research Centres (CRCs) as of 1 July 2011. This was decided by the relevant Grants Committee at its spring meeting in Bonn.

4 Jun 2011

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

A new therapy for type 1 diabetes? A promising treatment for deadly viruses? Does a common treatment for children with severe infection actually cause more harm than good? These are important questions being investigated by pediatric researchers at Mattel Children's Hospital UCLA.

4 Jun 2011

Medical researchers uncover a novel approach to treat Huntington's disease

Medical researchers may have uncovered a novel approach to treat an incurable and ultimately fatal neurodegenerative disease that affects hundreds of thousands of people.

3 Jun 2011

Patch-clamp recording reveals subtle differences between two neurotransmitter-gated ion channels

Using a high-resolution single-molecule study technique, University of Illinois researchers have seen the very subtle differences between two branches of an important family of neurotransmitter-gated ion channels.

3 Jun 2011

RegeneRx Thymosin beta 4 stimulates maturation of central nervous system progenitor cells

RegeneRx Biopharmaceuticals, Inc. has announced that researchers have found that Thymosin beta 4 (Tβ4), in a dose dependent manner, stimulates oligodendrogenesis, the process by which central nervous system progenitor cells become oligodendrocytes that secrete myelin, the covering of nerve fibers.

2 Jun 2011

Investigators to examine how Ephb2 gene causes ependymoma in children

Armed with new grant support, investigators at Nationwide Children's Hospital plan to examine how a common gene of the nervous system leads to the development of a devastating brain tumor, ependymoma.

2 Jun 2011

Heptares, AstraZeneca partner to discover and develop new GPCR drug targets

AstraZeneca and Heptares Therapeutics today announced they have entered a four-year collaboration focused on the potential discovery and development of new medicines targeting G-protein coupled receptors.

31 May 2011

Exposure to pesticides near any workplace increases risk of Parkinson's disease

In April 2009, researchers at UCLA announced they had discovered a link between Parkinson's disease and two chemicals commonly sprayed on crops to fight pests.

27 May 2011

Naturally occurring plant alkaloids could help prevent, delay memory loss linked with Alzheimer's

A family of naturally occurring plant compounds could help prevent or delay memory loss associated with Alzheimer's disease, according to a new study by the Translational Genomics Research Institute.

27 May 2011

Vatican newspaper article addresses condom use among married couples

Three days before the start of a Vatican conference focusing on "the centrality of care" in HIV/AIDS prevention and treatment, the Vatican's official newspaper, L'Osservatore Romano, on Tuesday printed a piece by Spanish theologian Juan Jose Perez-Soba arguing that married couples with one HIV-positive partner "should abstain from sex, because intercourse performed with a condom is, 'from the moral point of view, not a fully conjugal act,'" RNS/Beliefnet News reports.

26 May 2011

Investigators receive NIH grant to help move gene therapy for MPS IIIB toward clinical trials

Investigators at Nationwide Children's have received a grant from the National Institutes of Health to help move a therapy for MPS IIIB that has been shown effective in mice toward clinical trials in humans.

26 May 2011

Comprehensive insight into current neural stem cell research and therapies

A new article published by Cell Press in the May 26 issue of the journal Neuron provides comprehensive insight into the current status of neural stem cell research and the sometimes labyrinthine pathways leading to stem cell-based therapies.

26 May 2011

Evotec, PsychoGenics partner to offer integrated CNS drug discovery solutions

PsychoGenics Inc. today announced that it has entered into a strategic alliance with Evotec AG to provide integrated CNS drug discovery solutions to pharmaceutical and biotech companies.

25 May 2011

ImmunoCellular to present new ICT-107 Phase I trial data in glioblastoma multiforme at ASCO 2011

ImmunoCellular Therapeutics, Ltd today announced it will be presenting new data from the Phase I clinical trial of ICT-107, the Company's lead cancer vaccine candidate for the treatment of glioblastoma multiforme.

25 May 2011

Nanoscopic findings may lead to new experimental methods for early multiple sclerosis diagnosis

Laboratory studies by chemical engineers at UC Santa Barbara may lead to new experimental methods for early detection and diagnosis -- and to possible treatments -- for pathological tissues that are precursors to multiple sclerosis and similar diseases.

24 May 2011

OptiNose wins 200,000 NOK award for novel bi-directional nasal drug delivery technology

OptiNose Inc. announced that the Company has recently won the Oslo regional finals of the DnB NOR Innovation Award for its novel, bi-directional nasal drug delivery technology.

23 May 2011

Central Nervous System News and Research

New insights into understanding of neurological disorders

Survivors of childhood cancer at increased risk of developing subsequent primary neoplasms

Genentech's Avastin, chemotherapy Phase III combination study data on ovarian cancer presented at ASCO

Anti-ghrelin vaccine decreases food intake and increases calorie burning in mice

DFG to form new collaborative research centers as of 1 July 2011

UCLA pediatric investigators earn top accolades at TTCF Faculty Presentation Awards

Medical researchers uncover a novel approach to treat Huntington's disease

Patch-clamp recording reveals subtle differences between two neurotransmitter-gated ion channels

RegeneRx Thymosin beta 4 stimulates maturation of central nervous system progenitor cells

Investigators to examine how Ephb2 gene causes ependymoma in children

Heptares, AstraZeneca partner to discover and develop new GPCR drug targets

Exposure to pesticides near any workplace increases risk of Parkinson's disease

Naturally occurring plant alkaloids could help prevent, delay memory loss linked with Alzheimer's

Vatican newspaper article addresses condom use among married couples

Investigators receive NIH grant to help move gene therapy for MPS IIIB toward clinical trials

Comprehensive insight into current neural stem cell research and therapies

Evotec, PsychoGenics partner to offer integrated CNS drug discovery solutions

ImmunoCellular to present new ICT-107 Phase I trial data in glioblastoma multiforme at ASCO 2011

Nanoscopic findings may lead to new experimental methods for early multiple sclerosis diagnosis

OptiNose wins 200,000 NOK award for novel bi-directional nasal drug delivery technology

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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