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A global genetic surveillance gap for SARS-CoV-2

Now a new study posted to the medRxiv* preprint server provides a perspective on the global disparities surrounding SARS-CoV-2 genomic surveillance, their causes and consequences, and possible solutions to maximize the impact of pathogen genome sequencing for efforts on public health.

1 Sep 2021

Increased transmissibility drives SARS-CoV-2 variant spread, aided by immune escape

Numerous variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged over the last few months. Unfortunately, this has driven new coronavirus disease 2019 (COVID-19) waves, often more severe than before. A recent study posted to the medRxiv* preprint server discusses the characteristics of the variant that is responsible for this phenomenon.

31 Aug 2021

Post-infection vaccination produces potent neutralizing antibodies against SARS-CoV-2 variants

The best protection against new SARS-CoV-2 infections or reinfections may be obtained by a combination of vaccine-elicited and infection-induced antibodies.

31 Aug 2021

Marijuana legalization may increase the risk of alcohol and marijuana co-use among adolescents

A new study from the Prevention Research Center of the Pacific Institute for Research and Evaluation finds that recreational marijuana legalization may increase the risk of alcohol and marijuana co-use among adolescents.

31 Aug 2021

New study to investigate treatment of respiratory infections in children with tracheostomy

Each year, approximately 4,000 children undergo a tracheostomy- the surgical placement of a breathing tube-due to respiratory or neuromuscular disorders or chronic disease progression.

30 Aug 2021

Gitelman syndrome more common in Japanese population than previously reported

Clinical Fellow KONDO Atsushi and Professor NOZU Kandai et al. of Kobe University's Graduate School of Medicine have estimated the prevalence of Gitelman syndrome across different ethnicities using a genome database.

30 Aug 2021

Researchers urge neurologists to actively encourage vaccinations for Parkinson's patients

Patients with Parkinson's disease (PD) are at higher risk for vaccine-preventable respiratory illnesses. However, patients with advanced PD may have less access to vaccinations according to a new study published in the Journal of Parkinson's Disease.

30 Aug 2021

Have SARS-CoV-2 symptoms changed in the UK population over time?

A new paper compares changes in the symptoms due to COVID-19 over the course of the pandemic.

29 Aug 2021

$Study identifies drug with a positive effect on heart failure patients with preserved ejection fraction$

Study identifies drug with a positive effect on heart failure patients with preserved ejection fraction

Until now, patients with heart failure with preserved ejection fraction – the most common type of heart failure in the elderly – have had no access to evidenced-based treatments. For the first time, a large clinical trial led by Prof. Dr. Stefan Anker from Charité – Universitätsmedizin Berlin has identified a drug which has a distinctly positive effect on prognosis. In patients affected by this type of heart failure, the drug – empagliflozin – reduces the risk of hospitalization or cardiovascular death by 21 percent. The results of this research have been published in the New England Journal of Medicine.

28 Aug 2021

Moderate-vigorous physical activity found to be the most efficient at improving fitness

In the largest study performed to date to understand the relationship between habitual physical activity and physical fitness, researchers from Boston University School of Medicine (BUSM) have found that higher amount of time spent performing exercise (moderate-vigorous physical activity) and low-moderate level activity (steps) and less time spent sedentary, translated to greater physical fitness.

28 Aug 2021

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

Northwestern Medicine scientists continue to investigate all aspects of the COVID-19 pandemic: from molecular mechanisms of infection, to child hospitalization and single-dose vaccine response.

28 Aug 2021

Implantable cardiac monitors effectively detect serious arrhythmias in selected post-infarction patients

Remote monitoring of implantable cardiac monitors (ICMs) is highly effective for early detection of serious arrhythmias in high-risk post-infarction patients with cardiac autonomic dysfunction and moderately reduced ejection fraction.

27 Aug 2021

Ultra-processed food intake linked to increased risk of heart disease

Weekly consumption of ultra-processed food is linked with an increased risk of heart disease, according to research presented at ESC Congress 2021.

27 Aug 2021

FDA approves drug-free stroke rehabilitation system to treat upper extremity motor deficits

The U.S. Food and Drug Administration today approved the MicroTransponder Vivistim Paired VNS System (Vivistim System), a first-of-its-kind, drug-free rehabilitation system intended to treat moderate to severe upper extremity motor deficits associated with chronic ischemic stroke—a stroke caused by a blockage of blood flow to the brain with long-lasting symptoms—using vagus nerve stimulation (VNS).

27 Aug 2021

Hyfe’s smartphone cough-tracking app used in a groundbreaking epidemiological research

Hyfe, a cough monitoring smartphone app and digital diagnostics tool developed by an international team of scientists and public health professionals, recently announced that their technology is now being incorporated into groundbreaking research in Spain in partnership with the University of Navarra, and involving over 800 participants.

26 Aug 2021

Study shows school closures can be minimized by regular testing and vaccination against COVID-19

A new study discusses a novel model to determine age-specific differences in susceptibility of infection, contact patterns, and contagiousness to COVID-19.

25 Aug 2021

Scientists forecast healthcare burden of future COVID waves

The findings indicate that given the lower vaccine efficacy against the SARS-CoV-2 delta variant, France may face a large epidemic wave infecting 25% of the general population even with a 95% vaccine coverage. This, in turn, could affect the healthcare system in terms of hospital bed occupancy. The study is currently available on the medRxiv* preprint server.

25 Aug 2021

SARS-CoV-2 Delta variant associated with more breakthrough infections

The study highlights that compared to the previously circulating alpha variant, the delta variant is associated with higher infectious virus load and a lower level of humoral immunity in the upper respiratory tract. The study is currently available on the medRxiv* preprint server prior to peer review.

24 Aug 2021

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation results in the production of a truncated peptide with altered functionality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

24 Aug 2021

Extreme novel pandemics more likely to occur in the future, statistical study reveals

The COVID-19 pandemic may be the deadliest viral outbreak the world has seen in more than a century. But statistically, such extreme events aren't as rare as we may think, asserts a new analysis of novel disease outbreaks over the past 400 years.

24 Aug 2021

Frequency News and Research

A global genetic surveillance gap for SARS-CoV-2

Increased transmissibility drives SARS-CoV-2 variant spread, aided by immune escape

Post-infection vaccination produces potent neutralizing antibodies against SARS-CoV-2 variants

Marijuana legalization may increase the risk of alcohol and marijuana co-use among adolescents

New study to investigate treatment of respiratory infections in children with tracheostomy

Gitelman syndrome more common in Japanese population than previously reported

Researchers urge neurologists to actively encourage vaccinations for Parkinson's patients

Have SARS-CoV-2 symptoms changed in the UK population over time?

Study identifies drug with a positive effect on heart failure patients with preserved ejection fraction

Moderate-vigorous physical activity found to be the most efficient at improving fitness

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

Implantable cardiac monitors effectively detect serious arrhythmias in selected post-infarction patients

Ultra-processed food intake linked to increased risk of heart disease

FDA approves drug-free stroke rehabilitation system to treat upper extremity motor deficits

Hyfe’s smartphone cough-tracking app used in a groundbreaking epidemiological research

Study shows school closures can be minimized by regular testing and vaccination against COVID-19

Scientists forecast healthcare burden of future COVID waves

SARS-CoV-2 Delta variant associated with more breakthrough infections

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

Extreme novel pandemics more likely to occur in the future, statistical study reveals

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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