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An investigation of three SARS-CoV-2 mRNA doses in multiple sclerosis vaccine non-responders

A clinical study by a team of scientists from Norway aimed to assess the immunogenicity and safety of a third dose of COVID-19 mRNA vaccine in MS patients treated with anti-CD20 therapy or fingolimod. A preprint version of the study, which is yet to undergo peer review, is available on the medRxiv* server.

20 Oct 2021

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

A new study published in the journal Annals of Internal Medicine conducted systematic surveillance involving 2,397 HCWs who were fully vaccinated with the Pfizer-BioNTech BNT162 vaccine at the ASST Settelaghi hospitals, Italy, in February 2021.

19 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

COVID-19 protocols may remain important even for college campuses with 100% vaccine rates

Most universities are encouraging vaccination, and many have mandated vaccination for all students. Given the availability of effective vaccines, there is a growing need to reevaluate the importance of university COVID-19 protocols.

18 Oct 2021

Telehealth to the rescue for children’s mental health during COVID

A new study concludes that the lack of transportation led to impairments in child mental health services.

18 Oct 2021

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

Researchers from Singapore conducted a study to assess the spike protein-specific humoral and cellular immunity in Ad26.COV2.S vaccinated individuals either primed with Ad26.COV2.S only, or boosted with a homologous or heterologous second dose.

18 Oct 2021

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

To address the gaps in the knowledge, a team of researchers from the University of California and the Gladstone Institute of Virology conducted 39-parameter phenotyping by cytometry by time of flight (CyTOF) on 33 longitudinal specimens from 11 mRNA-vaccinated individuals, of which six had previously been infected and recovered from COVID-19.

18 Oct 2021

Researchers identify common side effects of three COVID-19 vaccines

COVID-19 vaccines remain the best tool in the pandemic toolbox against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). But they are not perfect; reports have surfaced of mild to severe side effects after vaccination. A new study from researchers in the Lampe & Company GmbH & Co. KG compared the severity of adverse events from each coronavirus vaccine.

17 Oct 2021

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

The efficacy and safety of a DNA-based vaccine are investigated, finding that the unique vaccine imparts a robust and long-lasting immunogenic response.

15 Oct 2021

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

The results of a phase 2 clinical trial featuring a SARS-CoV-2 recombinant protein vaccine developed by GlaxoSmithKline are reported, demonstrating a favorable immune response amongst both naïve and non-naïve adults with an acceptable safety profile.

15 Oct 2021

The military as a disease vector and COVID-19

A recent systematic review aimed to study existing evidence for the military being a historically relevant disease vector that has been overlooked during the COVID-19 pandemic.

15 Oct 2021

SARS-CoV-2 induces tissue immune memory

A new study reports that the SARS-CoV-2 induces protective tissue memory that includes both humoral and cellular elements to protect specific tissue sites.

14 Oct 2021

Researchers develop a cervical myelopathy screening tool using non-contact sensor and machine learning

Cervical myelopathy (CM) results from compression of the spinal cord in the neck and causes difficulty moving the fingers and unsteady gait.

13 Oct 2021

Rapid measurement of SARS-CoV-2 spike T-cells

Researchers measure SARS-CoV-2 T-cell responses in individuals vaccinated or in those who developed immunity from a prior natural infection.

12 Oct 2021

How can healthcare professionals help address climate change?

In this interview, we spoke to researchers about how healthcare professionals can help to address the health issues surrounding climate change.

12 Oct 2021

Research reveals components of Sinbis virus ribonucleoproteins

To address this gap in research regarding the understanding of post-replicative alphavirus RNPs, scientists have created a novel proteome-wide approach known as viral RNA interactome capture (vRIC). This study is available in the bioRxiv* preprint server while awaiting peer review.

11 Oct 2021

Frequency News and Research

An investigation of three SARS-CoV-2 mRNA doses in multiple sclerosis vaccine non-responders

Regular testing of SARS-CoV-2 positive vaccinated HCWs may reduce need for long quarantines

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

COVID-19 protocols may remain important even for college campuses with 100% vaccine rates

Telehealth to the rescue for children’s mental health during COVID

Study shows enhanced immunogenicity of heterologous boosting strategy in individuals primed with J&J vaccine

Research indicates that mRNA vaccine-induced T cells respond robustly to new SARS-CoV-2 variants

Researchers identify common side effects of three COVID-19 vaccines

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

The military as a disease vector and COVID-19

SARS-CoV-2 induces tissue immune memory

Researchers develop a cervical myelopathy screening tool using non-contact sensor and machine learning

Rapid measurement of SARS-CoV-2 spike T-cells

How can healthcare professionals help address climate change?

Research reveals components of Sinbis virus ribonucleoproteins

Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA

Higher COVID-19 hospitalization and mortality rates reported in rural America

Researchers use control systems engineering tools to personalize fitness tracker messages

Adapting biological research and development to COVID-19

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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