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miR-31 in primary tumor cells predicts lymph node metastasis in NSCLC patients

Determining whether a patient's lung cancer has spread to nearby lymph nodes is critical for identifying the most effective therapy, but it usually requires surgery. A new study suggests, however, that measuring levels of a particular molecule in a sample of tumor tissue might accurately answer the question.

25 Sep 2013

Discovery could help develop new treatments for blood diseases

Researchers in Melbourne, Australia, have found that even our immune system is subject to performance enhancement, with our bodies giving immune cells the boost they need to ensure the best team is selected to fight infections.

24 Sep 2013

Study sheds new light on the dark matter of genome

Using technology he helped develop, Vanderbilt University scientist Bryan Venters, Ph.D., has shed new light on the "dark matter" of the genome and has begun to explore a possible new approach to treating cancer.

19 Sep 2013

Neonatal hepatocytes show better thawing recovery than hepatocytes from adult livers

A research team in Spain has developed high-yield preparations of viable hepatocytes (liver cells) isolated for transplantation from cryopreserved (frozen), banked neonatal livers that ranged in age from one day to 23 days.

18 Sep 2013

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

New research shows that microRNA-486 is a potent tumor-suppressor molecule in lung cancer, and that the it helps regulate the proliferation and migration of lung-cancer cells, and the induction of programmed cell death, or apoptosis, in those cells.

17 Sep 2013

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.

17 Sep 2013

Pancreatic protein essential for maintaining functional state of beta cells

Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 - a beta-cell enriched transcription factor - is essential to maintaining the functional state of beta cells.

13 Sep 2013

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

Exposing young women and girls under the age of 20 to ionizing radiation can substantially raise the risk of their developing breast cancer later in life. Scientists may now know why. A collaborative study, in which Berkeley Lab researchers played a pivotal role, points to increased stem cell self-renewal and subsequent mammary stem cell enrichment as the culprits.

12 Sep 2013

Combined transplantation provides potential new therapy for repair of spinal cord injury

Following spinal cord injury, astrocyte proliferation and scar formation are the main factors inhibiting the regeneration and growth of spinal cord axons, leading to motor and sensory function loss below the level of spinal cord injury.

10 Sep 2013

TSRI scientists identify involvement of angiomotin protein in cancer

A team led by scientists from The Scripps Research Institute have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth.

6 Sep 2013

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

Unravelling the mechanisms of cardiac fibrosis will lead to the discovery of therapeutic target candidates for various cardiac diseases. FIBRO-TARGETS brings together eleven European expert teams from six different countries both from public research institutes and European biotechs.

5 Sep 2013

TSRI scientists discover isoform of angiomotin protein responsible for tumorigenesis

A team led by scientists from The Scripps Research Institute (TSRI) have shown that a protein once thought to inhibit the growth of tumors is instead required for initial tumor growth. The findings could point to a new approach to cancer treatment.

5 Sep 2013

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Case Western Reserve researchers have identified a genetic factor that blocks the blood vessel inflammation that can lead to heart attacks, strokes and other potentially life-threatening events.

5 Sep 2013

Boosting Your Brain Power With Sleep

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4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Research findings could lead to new therapeutic approaches for liver cancer

Liver cancer (Hepatocellular Carcinoma, HCC) usually arises as the result of a chronic, inflammatory liver disease. The most common causes here are excessive alcohol consumption as well as a high-fat diet and also chronic infection with the hepatitis viruses B and C. In the course of the inflammatory process, the liver cells (hepatocytes) die more frequently due to programmed cell death.

30 Aug 2013

Research suggests clingy blood platelets may offer hope for people with rheumatoid arthritis

No one likes clingy people, but "clingy" blood platelets may offer hope for millions of people with rheumatoid arthritis. According to new research findings published in The Journal of Leukocyte Biology, a sub population of immune cells (lymphocytes) known to play a significant role in rheumatoid arthritis has platelets attached to their surface.

30 Aug 2013

BTNL2 gene mutation that impacts immune function increases risk of prostate cancer

A team of researchers led by Janet Stanford, Ph.D., of Fred Hutchinson Cancer Research Center has discovered that mutations in the gene BTNL2, which encodes a protein involved in regulating T-cell proliferation and cytokine production - both of which impact immune function - increase the risk of developing prostate cancer.

30 Aug 2013

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine.

29 Aug 2013

Proliferation News and Research

miR-31 in primary tumor cells predicts lymph node metastasis in NSCLC patients

Discovery could help develop new treatments for blood diseases

Study sheds new light on the dark matter of genome

Neonatal hepatocytes show better thawing recovery than hepatocytes from adult livers

microRNA-486 found to be potent tumor-suppressor molecule in lung cancer

Researchers find mucus-regulating protein receptors out of control in uterine, pancreatic cancers

Pancreatic protein essential for maintaining functional state of beta cells

Exposing young girls to ionizing radiation can raise risk of breast cancer later in life

Combined transplantation provides potential new therapy for repair of spinal cord injury

TSRI scientists identify involvement of angiomotin protein in cancer

FIBRO-TARGETS project aims to identify mechanisms involved in MIF, define therapeutic approaches

TSRI scientists discover isoform of angiomotin protein responsible for tumorigenesis

Case Western researchers establish Kruppel-like factors as master regulators of vascular health

Boosting Your Brain Power With Sleep

Study: Changes in expression of various isoforms might play role in cancer development

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Research findings could lead to new therapeutic approaches for liver cancer

Research suggests clingy blood platelets may offer hope for people with rheumatoid arthritis

BTNL2 gene mutation that impacts immune function increases risk of prostate cancer

Pulmonary hypertension may be caused by molecular pathway that damages blood vessels

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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