Genome News and Research

RSS

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage.

12 Jul 2022

Researchers report a non-canonical RNA secondary structure present in monkeypox virus variants

Researchers described the evolutionary profile of the monkeypox virus.

12 Jul 2022

What is the effectiveness of the fourth dose mRNA vaccination against the Omicron variant?

Researchers evaluated the efficacy of the fourth vaccine dose against COVID-19.

11 Jul 2022

The interplay of family history and genome-wide polygenic risk scores across 24 common diseases

A new study has investigated the interplay of FH and genome-wide PRS

11 Jul 2022

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

In a recent study published in the Nature journal, researchers assessed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission using wastewater sequencing.

11 Jul 2022

Salk professor wins $2 million to gain better understanding of cassava genetics

Research Professor Todd Michael will receive nearly $2 million from the Bill & Melinda Gates Foundation to sequence the genomes of multiple lineages of the cassava plant, a large starchy root vegetable also known as yuca root consumed in more than 80 countries around the world.

8 Jul 2022

Scientists uncover how the innate immune system detects and fights HIV-1

Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its uncanny ability to evade the immune system.

8 Jul 2022

Study illustrates how the use of whole exome sequencing can better predict treatment response

Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced stage cancers.

8 Jul 2022

Study offers a new understanding of the evolutionary diversification of KNL2 gene

In living organisms cells divide and reproduce in two ways, mitosis and meiosis. Mitosis results in two identical daughter cells, whereas meiosis results in four sex cells.

8 Jul 2022

Genetically-enhanced biocontrols can help eradicate invasive alien mammals

Invasive alien mammals can have catastrophic impacts on native flora and fauna, causing species extinctions and driving profound environmental change.

8 Jul 2022

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

A collaboration including researchers from Kobe University, University of Tokyo and Tohoku University has successfully identified and disrupted genes in the yeast Pichia pastoris (1) in order to increase its secretory production of useful proteins (2).

8 Jul 2022

The putative impact of vitamin D receptor gene polymorphisms on SARS-CoV-2 infection among different variants

Researchers assessed the association between SARS-CoV-2 variants and the vitamin D receptor gene.

8 Jul 2022

Study suggests spironolactone may improve clinical outcomes in COVID-19

Researchers performed an integrative analysis of clinical outcomes and viral entry networks in severe COVID-19 infection.

8 Jul 2022

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Sickle cell disease is an extremely debilitating condition that affects up to 40% of the population in African countries, with patients suffering episodes of excruciating pain, organ damage and reduced life-expectancy.

7 Jul 2022

Chicoric acid a potential candidate for COVID-19 treatment

An article under review in the Scientific Reports journal and currently available on the Research Square* preprint server reports on chicoric acid (CA) as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jul 2022

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

The Damon Runyon Cancer Research Foundation has named five new Damon Runyon Clinical Investigators.

6 Jul 2022

Biologists shed light on the evolution and consequences of selfish genetic elements

The human genome is littered with "selfish genetic elements," which do not seem to benefit their hosts, but instead seek only to propagate themselves.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

New model reveals cancer-driving mutations

In this interview, News-Medical speaks to Maxwell Sherman, an MIT graduate student and one of the lead authors of a study that used a new method to investigate cancer genomes.

6 Jul 2022

Researchers explore how diet and feeding patterns affect intestinal microbes

An estimated 500 to 1,000 bacterial species reside in each person's gut, perhaps numbering 100,000 trillion microorganisms.

5 Jul 2022

Genome News and Research

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Researchers report a non-canonical RNA secondary structure present in monkeypox virus variants

What is the effectiveness of the fourth dose mRNA vaccination against the Omicron variant?

The interplay of family history and genome-wide polygenic risk scores across 24 common diseases

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

Salk professor wins $2 million to gain better understanding of cassava genetics

Scientists uncover how the innate immune system detects and fights HIV-1

Study illustrates how the use of whole exome sequencing can better predict treatment response

Study offers a new understanding of the evolutionary diversification of KNL2 gene

Genetically-enhanced biocontrols can help eradicate invasive alien mammals

Disrupting genes in the yeast Pichia pastori to increase its secretory production of useful proteins

The putative impact of vitamin D receptor gene polymorphisms on SARS-CoV-2 infection among different variants

Study suggests spironolactone may improve clinical outcomes in COVID-19

Novel gene-based therapies for sickle cell disease rely on finding the right mouse for the job

Chicoric acid a potential candidate for COVID-19 treatment

Damon Runyon Cancer Research Foundation names five new Damon Runyon Clinical Investigators

Biologists shed light on the evolution and consequences of selfish genetic elements

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

New model reveals cancer-driving mutations

Researchers explore how diet and feeding patterns affect intestinal microbes

The art of CRISPR: The power and promise of gene editing eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News