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Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.

5 Apr 2020

New molecular mechanism that regulates the sentinel cells of the immune system

A study suggests that it may be possible to regulate macrophages with drugs that modulate the nuclear receptor RXR.

3 Apr 2020

Visualization tool enables doctors to get an overview of critical care bed capacities

Computer scientists in the team led by Professor Daniel Keim, professor of data analysis and visualization at the University of Konstanz, developed a visualization tool called "Coronavis".

2 Apr 2020

Russian Science Foundation funds eleven Kazan University projects

Eleven Kazan University projects receive funding from the Russian Science Foundation. The results were published on 1st April 2020.

2 Apr 2020

How (easily) does the novel coronavirus spread?

Viruses are tiny bundles of DNA or RNA which have the ability to infect host cells, hijack the machinery of the host cell and then replicate. Once the host cell’s resources are exhausted, the viral particles are released to infect other cells. In this way, the viruses ensure their survival, often at the expense of the host.

1 Apr 2020

What are coronaviruses and COVID-19?

The current COVID-19 pandemic is caused by a novel coronavirus called SARS-CoV-2, or severe acute respiratory syndrome coronavirus 2. Coronavirus disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2.

1 Apr 2020

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit.

1 Apr 2020

ECMO support in Shanghai provides guidance for managing COVID-19 patients worldwide

The initial experience of extracorporeal membrane oxygenation management for coronavirus 2019 (COVID-19) patients in Shanghai, China provides guidance for management of critically ill COVID-19 patients worldwide, reports a study in the ASAIO Journal.

1 Apr 2020

Inhibiting the iron transport could halt tuberculosis

The bacteria that cause tuberculosis need iron to survive. Researchers at the University of Zurich have now solved the first detailed structure of the transport protein responsible for the iron supply.

1 Apr 2020

Pancreatitis drug Nafamostat shows promise for coronavirus

With the increasing number of infections across the globe, scientists have resorted to studying existing drugs in the hope of discovering a cure for the coronavirus disease (COVID-19). A team of researchers has found that an existing drug, Nafamostat or Fusan, a drug used to treat acute pancreatitis, may effectively block the process used by the novel coronavirus to spread and cause illness.

1 Apr 2020

Antihypertensive drugs may protect against COVID-19 in heart patients

Common drugs used in high blood pressure, heart failure, and diabetic patients with kidney damage, including angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs), could be protective in patients with COVID-19.

31 Mar 2020

Three Australian experts explain the course of COVID-19

Researchers have been studying the ongoing pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) closely since its beginning in December 2019. To date, the virus has infected over 850,000 individuals across the globe and killed over 41,000.

31 Mar 2020

Origins of SARS-CoV-2 – natural or man-made?

With over 780,000 individuals across the world infected and over 37,000 dead, the world is gripped by the pandemic caused by the novel strain of coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

30 Mar 2020

New microfluidic chip can mimic hypoxic conditions after a heart attack

Researchers led by biomedical engineers at Tufts University invented a microfluidic chip containing cardiac cells that is capable of mimicking hypoxic conditions following a heart attack - specifically when an artery is blocked in the heart and then unblocked after treatment.

30 Mar 2020

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

One promising way to treat diabetes is with transplanted islet cells that produce insulin when blood sugar levels get too low.

30 Mar 2020

Study reveals new mechanism underlying organelle communication in brown fat cells

In recent years, brown fat has garnered increasing attention as the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease and diabetes.

30 Mar 2020

COVID-19 and its effects on the cardiovascular system

Researcher have reviewed the evidence showing the effects of the SARS-CoV-2 or novel coronavirus infection (COVID-19) on the cardiovascular system. Their study titled, “Potential Effects of Coronaviruses on the Cardiovascular System: A Review,” was published in the latest issue of JAMA Cardiology.

29 Mar 2020

Researchers enlist the help of citizen scientists to design new drugs against coronavirus

The best thing most of us can do to fight COVID-19 is stay home, to curb the respiratory disease's spread. But anyone with a computer can pitch in more actively too: by helping scientists design drugs to combat the virus now responsible for hundreds of thousands of infections worldwide.

27 Mar 2020

SLAC structural biologist discovers a strange cavity in key tuberculosis protein

Researchers from the Department of Energy’s SLAC National Accelerator Laboratory have discovered a strange new feature of a protein that’s thought to be important in the development of tuberculosis: The protein contains a “huge” interior pocket, the likes of which has never before been seen, that appears capable of passing a wide range of other molecules into the bacterial cell.

27 Mar 2020

A genetic toolkit to produce multifunctional magnetic nanoparticles

Magnetic bacteria might soon be used for the production of novel biomaterials. A team of microbiologists at the University of Bayreuth led by Prof. Dr. Dirk Schüler developed a modular system for the genetic reprogramming of bacteria, thereby turning the organisms into cell factories for multifunctional magnetic nanoparticles that combine various useful functions and properties.

25 Mar 2020

Membrane News and Research

Researchers uncover mechanism by which gene mutations potentially give rise to kidney disease

New molecular mechanism that regulates the sentinel cells of the immune system

Visualization tool enables doctors to get an overview of critical care bed capacities

Russian Science Foundation funds eleven Kazan University projects

How (easily) does the novel coronavirus spread?

What are coronaviruses and COVID-19?

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

ECMO support in Shanghai provides guidance for managing COVID-19 patients worldwide

Inhibiting the iron transport could halt tuberculosis

Pancreatitis drug Nafamostat shows promise for coronavirus

Antihypertensive drugs may protect against COVID-19 in heart patients

Three Australian experts explain the course of COVID-19

Origins of SARS-CoV-2 – natural or man-made?

New microfluidic chip can mimic hypoxic conditions after a heart attack

'Living drug factories' could be used to achieve long-term treatment of chronic diseases

Study reveals new mechanism underlying organelle communication in brown fat cells

COVID-19 and its effects on the cardiovascular system

Researchers enlist the help of citizen scientists to design new drugs against coronavirus

SLAC structural biologist discovers a strange cavity in key tuberculosis protein

A genetic toolkit to produce multifunctional magnetic nanoparticles

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