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Senolytic agent ABT-263 mitigates GI cancer risk after radiation exposure

A new research paper was published by Aging (Aging-US) on January 8, 2025, in Volume 17, Issue 1, titled "Senolytic agent ABT-263 mitigates low- and high-LET radiation-induced gastrointestinal cancer development in Apc1638N/+ mice."

18 Feb 2025

Fungal component may protect against flu-related lung damage

A component found in all fungi may provide a shield against flu-related lung damage, according to a new study.

18 Feb 2025

Swimming in lakes may increase risk of Legionella infection

Swimming in some lakes with still water can lead to infection with Legionella, bacteria that can cause pneumonia, and people who engage in open water swimming should be aware of this risk, say the authors of a practice article published in CMAJ.

18 Feb 2025

Gene therapy breakthrough offers hope for severe Dravet syndrome cases

AAV-Navβ1 gene therapy effectively reduces seizures and prolongs life in a mouse model of SCN1B-linked Dravet syndrome, paving the way for future treatments.

18 Feb 2025

Cancer-free for 18 years: CAR-T therapy sets new milestone in neuroblastoma treatment

A groundbreaking study in Nature Medicine reveals that GD2 CAR-T cell therapy can lead to long-term remission in children with neuroblastoma, with one patient remaining cancer-free for over 18 years.

17 Feb 2025

Sweat fails to match blood in tracking inflammation after heart attacks

Researchers found that while sweat biomarkers remain stable, plasma biomarkers show significant inflammatory changes after a heart attack, highlighting the limitations of sweat analysis for tracking recovery.

17 Feb 2025

NIDUS-Family care package reduces dementia support costs

The NIDUS-Family package of care uses goal setting to help people with dementia live well at home for longer.

17 Feb 2025

Lecanemab and donanemab slow Alzheimer’s decline, but is the benefit worth the cost?

Study finds that disease-modifying therapies for Alzheimer’s, lecanemab and donanemab, can extend independence in daily activities by up to 13 months, though their clinical relevance remains debated.

17 Feb 2025

Diabetes fuels antibiotic resistance, worsening infections and treatment challenges

A new study reveals that diabetes significantly accelerates the emergence and spread of antibiotic-resistant Staphylococcus aureus infections, highlighting a major public health concern.

17 Feb 2025

AI tool speeds up patient screening for heart failure trials

Artificial intelligence (AI) can rapidly screen patients for clinical trial enrollment, according to a new study published in JAMA and led by Mass General Brigham researchers.

17 Feb 2025

Innovative photodynamic therapy targets melanoma with light-activated dyes

Melanoma is one of the most aggressive skin cancers, with over 300,000 new cases reported worldwide each year. In Europe, the number of diagnoses has been rising rapidly.

17 Feb 2025

New gene switch may lead to precise treatments for metabolic diseases

ETH researchers have developed a new gene switch that can be activated using a commercially available nitroglycerine patch applied to the skin.

17 Feb 2025

Breakthrough technology enables mRNA delivery across the blood-brain barrier

Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

17 Feb 2025

Therapy dogs help first-year students cope with stress, depression, and anxiety

Therapy dog programs show promise in supporting university students' mental health, reducing anxiety and depression during their first semester adjustments.

17 Feb 2025

Can AI be your therapist? Study shows ChatGPT outperforms professionals in key areas

AI-assisted mental health care is evolving, with ChatGPT-4 outperforming therapists in empathy and cultural competence, raising implications for psychotherapy.

17 Feb 2025

Gene therapy shows promise in treating SCN1B-linked epileptic encephalopathies

Dravet syndrome and other developmental epileptic encephalopathies are rare but devastating conditions that cause a host of symptoms in children, including seizures, intellectual disability, and even sudden death.

14 Feb 2025

UVA receives $9.3 million NIH grant for ketamine seizure treatment trial

University of Virginia Brain Institute and School of Medicine researchers have received an initial $9.3 million award from the National Institutes of Health for a $30 million clinical trial to determine if the powerful anesthetic ketamine can save patients from prolonged, life-threatening grand mal seizures that won't respond to other treatments.

14 Feb 2025

New gut-on-chip model could revolutionize immunotherapy for melanoma

A team of researchers from the European Institute of Oncology and the Politecnico di Milano, coordinated by Luigi Nezi, Team Leader of the Department of Experimental Oncology, European Institute of Oncology, and Marco Rasponi, Full Professor of the Department of Electronics, Informatics and Bioengineering, Politecnico di Milano, have developed a "gut-on-chip" (a miniature model of the human intestine on a chip-sized device) capable of reproducing the main features of intestinal inflammation and of predicting the response of melanoma patients to immunotherapy treatment.

14 Feb 2025

Researchers uncover the brain mechanism behind ketamine's action

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic.

14 Feb 2025

Atherosclerosis detection in lung cancer patients through CT scans

Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart disease, according to a new study being presented at ACC's Advancing the Cardiovascular Care of the Oncology Patient course.

14 Feb 2025