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Researchers develop artificial adrenal system in animal model

If the function of the adrenal gland is disturbed it does not produce enough stress-adjusting messengers. The results are serious and cause life-threatening diseases. Under the direction of Prof. Dr. Stefan R. Bornstein of the university hospital Carl Gustav Carus researchers developed an artificial adrenal system together with the medicine Nobel Prize Laureate Prof. Dr. Andrew Schally in an animal model.

19 Feb 2015

SLU researchers halt fatty liver disease in animal model

Doctors believe that up to 30 percent of the U.S. population may have fat accumulation in the liver, known as non-alcoholic fatty liver disease (NAFLD), that can lead to a range of damaging health consequences.

18 Feb 2015

TKI introduction improves French CML patient survival

Real-world study findings from France show the significant impact tyrosine kinase inhibitor treatment has had on the survival of patients with Philadelphia chromosome-positive chronic myeloid leukaemia.

17 Feb 2015

Rutgers patient gets second chance at life following liver transplant

Mati Muñoz is 65 years old - filled with the enthusiastic energy that comes with a second chance at life. A decade ago, says Muñoz, who lives in Woodbridge Township, N.J., her liver was being destroyed by hepatitis C, a viral disease she believes she contracted as a girl in her native Cuba from a poorly sterilized needle used in a medical procedure.

17 Feb 2015

Eight clinical researchers selected as finalists for Outstanding Investigator Award at Cardiology 2015

Pediatric cardiology researchers and clinicians from numerous centers from around the world are gathering at the Cardiology 2015: the 18th Annual Update on Pediatric and Congenital Cardiovascular Disease conference, sponsored by The Children's Hospital of Philadelphia and Phoenix Children's Hospital on Feb. 11 to Feb. 15 in Scottsdale, Ariz.

16 Feb 2015

Study shows that plant-based vegan diet may lower heart disease risk in obese children

Obese children who begin a low-fat, plant-based vegan diet may lower their risk of heart disease through improvements in their weight, blood pressure, body mass index, cholesterol levels, insulin sensitivity, and high-sensitivity C-reactive, according to Cleveland Clinic research published online today by The Journal of Pediatrics.

16 Feb 2015

Jazz Pharmaceuticals to present defibrotide results for hepatic VOD at BMT Tandem meetings

Jazz Pharmaceuticals plc announced today that researchers will present data on the use of defibrotide, an investigational medicine being studied in the United States (U.S.) for the treatment of hepatic veno-occlusive disease (VOD), a rare, potentially life-threatening, early complication in patients undergoing hematopoietic stem-cell transplantation (HSCT) therapy.

13 Feb 2015

Gift of Hope Organ & Tissue Donor Network saves record number of lives in 2014

February 14th is National Donor Day. To celebrate, Gift of Hope Organ & Tissue Donor Network announced a record number of lives saved by helping 334 donors and their families donate 1,020 organs to patients waiting for a transplant, giving them a second chance at life last year.

13 Feb 2015

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

In May 2015 Atlanta will host Biotechnology and the Ethical Imagination: A Global Summit (BEINGS), an international summit drawing together the world's thought leaders on the highly debated issues of cellular biotechnology.

13 Feb 2015

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Astute Medical, Inc., developer of the NephroCheck® Test, today previewed the upcoming AKI & CRRT 2015 conference to be held in San Diego from February 17 to February 20.

13 Feb 2015

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

Stem cell transplants may be more effective than the drug mitoxantrone for people with severe cases of multiple sclerosis (MS), according to a new study published in the February 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Feb 2015

Longer donor leukocyte telomere length linked to improved survival following HCT

Among patients with severe aplastic anemia who received stem cell transplant from an unrelated donor, longer leukocyte (white blood cells) telomere length (a structure at the end of a chromosome) was associated with increased overall survival at 5 years, according to a study in the February 10 issue of JAMA.

12 Feb 2015

Despite growing shortage of donor hearts, surgeons, transplant centers reject marginal hearts

Surgeons and transplant centers nationwide increasingly have rejected hearts donated for transplantation despite a growing need for them, according to a new study by researchers at the Stanford University School of Medicine.

12 Feb 2015

Synthetic DNA gel could bring researchers closer to printing artificial organs

A two-part water-based gel made of synthetic DNA and peptide could bring the inventors of a 3D bio printer closer to being able to print organs for transplant, or to replace animal testing. The teams led by Dongsheng Liu (Tsinghua University) and Will Shu (Heriot-Watt University) faced two main challenges: finding a matrix or scaffold to support the live cells in 3D, and being able to produce a consistent product which would not be rejected by transplant recipients.

11 Feb 2015

New NIH grant to help restore function after spinal cord injury

Restoring function after spinal cord injury, which damages the connections that carry messages from the brain to the body and back, depends on forming new connections between the surviving nerve cells. While there are some delicate surgical techniques that reconnect the nerves, researchers are also looking at ways to restore the connections themselves at a cellular level.

10 Feb 2015

New research provides hope for treating stroke using HUCBCs

Researchers have known that transplanted human umbilical cord cells (HUCBCs) can have a restorative effect on the brain and brain function following a stroke. However, just how the cells exert their therapeutic effects has not been clear. Now, a research team from the University of South Florida using animal models of stroke has found that the HUCBCs are most beneficial in preventing neuron loss when the Akt signaling pathway is activated by secretions from the HUCBCs and that Akt activation subsequently impacts a specific gene involved in reducing inflammation.

10 Feb 2015

Japanese researchers explore use of bone marrow transplants to treat hypophosphatasia

Recent research carried out by a team of researchers in Japan has investigated the use of bone marrow transplants (BMTs) to treat hypophosphatasia (HPP). In this study, the researchers carried out BMT for two infants with HPP in combination with allogenic (other-donated) mesenchymal stem cell transplants (MSCTs). The allogenic MSC donors were a parent of the infant.

10 Feb 2015

Researchers win $2.5 million DARPA contract to study prosthetic limb technology

A research team led by Paul Marasco, Ph.D., of Cleveland Clinic's Lerner Research Institute, has won a $2.5 million contract from the Defense Advanced Research Projects Agency. The contract was awarded through DARPA's new Hand Proprioception and Touch Interfaces (HAPTIX) program, which aims to deliver naturalistic sensations to amputees and enable better control over their prosthetic limbs through direct connections to users' nervous systems.

10 Feb 2015

Risks and benefits of fecal microbiota transplant

A woman successfully treated for a recurrent Clostridium difficile infection with stool from an overweight donor rapidly gained weight herself afterwards, becoming obese, according to a case report published in the new journal Open Forum Infectious Diseases.

9 Feb 2015

Researchers pinpoint key moments at which intervening decreases risk of death in hypertension patients

High blood pressure is the most common risk factor for heart disease and death worldwide, and yet the answers to some of the most basic questions about how to manage it - when to introduce new medications, intensify treatment or re-evaluate a patient - remain unclear. In a new study published this week in the British Medical Journal, researchers from Brigham and Women's Hospital examined the outcomes of 88,000 adults with hypertension to pinpoint the precise high-blood-pressure level and critical time points at which intervening was tied to a decrease in the risk of death.

9 Feb 2015

Transplant News and Research

Researchers develop artificial adrenal system in animal model

SLU researchers halt fatty liver disease in animal model

TKI introduction improves French CML patient survival

Rutgers patient gets second chance at life following liver transplant

Eight clinical researchers selected as finalists for Outstanding Investigator Award at Cardiology 2015

Study shows that plant-based vegan diet may lower heart disease risk in obese children

Jazz Pharmaceuticals to present defibrotide results for hepatic VOD at BMT Tandem meetings

Gift of Hope Organ & Tissue Donor Network saves record number of lives in 2014

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

Longer donor leukocyte telomere length linked to improved survival following HCT

Despite growing shortage of donor hearts, surgeons, transplant centers reject marginal hearts

Synthetic DNA gel could bring researchers closer to printing artificial organs

New NIH grant to help restore function after spinal cord injury

New research provides hope for treating stroke using HUCBCs

Japanese researchers explore use of bone marrow transplants to treat hypophosphatasia

Researchers win $2.5 million DARPA contract to study prosthetic limb technology

Risks and benefits of fecal microbiota transplant

Researchers pinpoint key moments at which intervening decreases risk of death in hypertension patients

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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