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Vitamin B3 supplementation during pregnancy may prevent birth defects, in-vivo study suggests

Supplementing the diet with vitamin B3 during pregnancy may treat the molecular deficiencies in women that can lead to birth defects, according to a landmark study in Australia. Over the last 12 years, developmental geneticist Sally Dunwoodie (Victor Chang Cardiac Research Institute, Sydney) and team have been studying the genes that influence fetal heart and bone development.

10 Aug 2017

Tiny lab-grown structures that resemble amniotic sac may help in infertility research

The first few weeks after sperm meets egg still hold many mysteries. Among them: what causes the process to fail, leading to many cases of infertility.

8 Aug 2017

Herbal remedy plants show promise to combat cancer

Herbal remedy plants native to Saudi Arabia are shown to have potential as treatments for cancer. Researchers from KAUST have been searching locally for plants that have potential for use to combat cancer.

7 Aug 2017

Vascularized 3D bioprinted liver tissue offers more accurate system for drug toxicity testing

Artificially constructed human tissues and organs have been developed with a number of different purposes in mind, from advanced robotics and novel materials to drug screening.

3 Aug 2017

Gene-therapy administered through skin transplants could enable treatment of many diseases

A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range of gene-based therapies to treat many human diseases.

3 Aug 2017

SNMMI recognizes contributions to nuclear medicine and molecular imaging at 2017 annual meeting

The Society of Nuclear Medicine and Molecular Imaging (SNMMI), an international scientific and medical organization, recognized contributions to the field of nuclear medicine and molecular imaging during its 2017 Annual Meeting in Denver, Colorado. Several awards ceremonies were held to recognize the valuable role SNMMI members play in advancing the diagnosis and treatment of heart disease, cancer and neurological conditions.

2 Aug 2017

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

The initiating oncogenic event in almost half of human lung adenocarcinomas is still unknown, a fact that complicates the development of selective targeted therapies.

2 Aug 2017

Researchers develop soft robotic arm for endoscopes to assist in surgical procedures

Flexible endoscopes can snake through narrow passages to treat difficult to reach areas of the body. However, once they arrive at their target, these devices rely on rigid surgical tools to manipulate or remove tissue.

2 Aug 2017

MR Solutions’ dry magnet system provides high resolution imaging within compact footprint

When it comes to choosing a preclinical MRI imaging system there is no need to compromise – MR Solutions’ 9.4T cryogen free, or dry magnet system provides state of the art high resolution imaging within a compact footprint.

2 Aug 2017

Novel imaging tracer can help assess patient’s rupture risk for abdominal aortic aneurysm

Yale University researchers have developed a way in which medical imaging could potentially be used to assess a patient's rupture risk for abdominal aortic aneurysm.

1 Aug 2017

Proposed machine learning-based framework predicts FGR pregnancies with high accuracy

During the millions of pregnancies that occur in the United States every year, expectant moms learn oodles about their developing fetuses over months of gestation.

31 Jul 2017

DNA-sensing mechanism of innate immune system controls cellular senescence

Cells in the body or in cultures eventually stop replicating. This phenomenon is called "senescence" and is triggered by shortening of telomeres, oxidative stress or genetic damage to the cells, either acute or simply due to the cell growing "old".

31 Jul 2017

Researchers create unique thermal ablation system for transdermal drug delivery

Many diseases are treated with protein-based drugs. However, due to the size of the molecules, the only effective delivery method is through injection, which can suffer from low patient compliance.

27 Jul 2017

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

Colorectal cancer is fairly treatable when caught early with regular screenings, but it is still the second-leading cause of cancer-related deaths in American men and the third-leading cause in women.

17 Jul 2017

Scientists uncover new gene therapy treatment routes for motor neurone disease

Scientists investigating the genetic causes and altered functioning of nerve cells in motor neurone disease (MND) have discovered a new mechanism that could lead to fresh treatment approaches for one of the most common forms of the disease.

14 Jul 2017

EPFL researchers identify social rank as determining factor for vulnerability to stress

Stress is a major risk factor for a range of psychopathologies. However, stress does not affect everyone equally: in the face of sustained adversity, some people develop depression symptoms while others adapt and remain resilient.

13 Jul 2017

Researchers develop metal-free contrast agent that could be safer for high-risk patients

To enhance the visibility of organs as they are scanned with magnetic resonance imaging (MRI), patients are usually injected with a compound known as a contrast agent before going into the scanner. The most commonly used MRI contrast agents are based on the metal gadolinium; however, these metal compounds can be harmful for young children or people with kidney problems.

13 Jul 2017

MPFI researchers reveal new technique to probe function of cerebellar interneurons

The cerebellum is an area of brain at the back of your head involved in movement. Its neuronal circuitry is relatively simple compared to other areas, but scientists still have a lot left to learn regarding its role in motor control and motor learning.

13 Jul 2017

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

ERYTECH Pharma, a French clinical-stage biopharmaceutical company developing innovative therapies for rare forms of cancer and orphan diseases, today announced that it has entered into a research collaboration with Queen's University in Canada to advance the preclinical development of ERYTECH's eryminase program specifically for the treatment of arginase-1 deficiency, a rare and severe metabolic disorder related to arginine metabolism.

12 Jul 2017

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

A groundbreaking advancement in materials from Northwestern University could potentially help patients requiring stem cell therapies for spinal cord injuries, stroke, Parkinson's disease, Alzheimer's disease, arthritic joints or any other condition requiring tissue regeneration, according to a new study.

10 Jul 2017

in vivo News and Research

Vitamin B3 supplementation during pregnancy may prevent birth defects, in-vivo study suggests

Tiny lab-grown structures that resemble amniotic sac may help in infertility research

Herbal remedy plants show promise to combat cancer

Vascularized 3D bioprinted liver tissue offers more accurate system for drug toxicity testing

Gene-therapy administered through skin transplants could enable treatment of many diseases

SNMMI recognizes contributions to nuclear medicine and molecular imaging at 2017 annual meeting

Kinase-inactive BRAF mutation triggers lung adenocarcinoma development

Researchers develop soft robotic arm for endoscopes to assist in surgical procedures

MR Solutions’ dry magnet system provides high resolution imaging within compact footprint

Novel imaging tracer can help assess patient’s rupture risk for abdominal aortic aneurysm

Proposed machine learning-based framework predicts FGR pregnancies with high accuracy

DNA-sensing mechanism of innate immune system controls cellular senescence

Researchers create unique thermal ablation system for transdermal drug delivery

Bacterium S. gallolyticus appears to actively promote development of colorectal cancer

Scientists uncover new gene therapy treatment routes for motor neurone disease

EPFL researchers identify social rank as determining factor for vulnerability to stress

Researchers develop metal-free contrast agent that could be safer for high-risk patients

MPFI researchers reveal new technique to probe function of cerebellar interneurons

ERYTECH partners with Queen’s University to advance its product candidate for treating arginase-1 deficiency

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

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