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Study reveals PEA-15 protein can enhance cancer cell proliferation

A new study from the University of Hawaii Cancer Center reveals that PEA-15, a protein previously shown to slow ovarian tumor growth and metastasis, can alternatively enhance tumor formation in kidney cells carrying a mutation in a cancer-promoting gene called H-Ras.

22 Nov 2011

Despite market constraints, the drug market for key hospital-treated infections will increase: Report

Decision Resources finds that the drug market for key hospital-treated infections that are of high interest to drug developers—most notably nosocomial pneumonia, bloodstream infections, skin and skin structure/surgical site infections and urinary tract infections—will increase from $3.3 billion in 2010 to just over $4 billion in 2020 in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan.

21 Nov 2011

Covidien to acquire BÂRRX Medical

Covidien, a leading global provider of healthcare products and a world leader in advanced energy-based devices, today announced a definitive agreement to acquire BÂRRX Medical, Inc. BÂRRX is the leader in treatment of Barrett's esophagus syndrome using bipolar radiofrequency (RF) ablation devices.

21 Nov 2011

2011 National Report Card on Lung Cancer notes significant change in grade for early detection

Today, Lung Cancer Alliance (LCA), the leading national support and advocacy voice for those at risk for or living with lung cancer, issued its annual 2011 National Report Card on Lung Cancer, an overall assessment of the nation's response to the continuing high mortality of lung cancer, the leading cause of cancer death.

21 Nov 2011

PLoS ONE publishes study on darinaparsin, a multivalent chemotherapeutic

ZIOPHARM Oncology, Inc. announced today the publication of a darinaparsin (Zinapar or ZIO-101) study in the PLoS ONE, an international, peer-reviewed, open-access, online publication of the Public Library of Science.

21 Nov 2011

Multi-center cabozantinib trial for hormone receptor-positive breast cancer with bone metastases initiated

Exelixis, Inc. today announced the initiation of an investigator-sponsored trial of cabozantinib in women with hormone receptor-positive breast cancer with bone metastases.

21 Nov 2011

Adeona to develop and commercialize DNA-based therapeutic for PAH using Intrexon technology

Adeona Pharmaceuticals, Inc., and the Human Therapeutics Division of Intrexon Corporation, announced today the formation of a global exclusive channel collaboration through which Adeona intends to develop and commercialize a DNA-based therapeutic using Intrexon's UltraVector platform and RheoSwitch Therapeutic System for the treatment of pulmonary arterial hypertension (PAH).

21 Nov 2011

FDA grants HDE marketing approval for BSD-2000 Hyperthermia System to treat cervical cancer

BSD Medical Corporation, a leading provider of medical systems that utilize heat therapy to treat cancer, announced today that the Company has obtained Humanitarian Device Exemption (HDE) marketing approval for the BSD-2000 Hyperthermia System (BSD-2000) from the U.S. Food and Drug Administration.

21 Nov 2011

OTS to market and disribute RaySearch's RayStation in South Korea

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21 Nov 2011

Convergence commences CNV2197944 multiple ascending dose Phase I study for chronic pain

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines, today announces that the multiple ascending dose Phase I study of the novel, first in class calcium channel blocker CNV2197944, for the treatment of chronic pain has been initiated.

21 Nov 2011

PEPFAR Scientific Advisory Board report offers six recommended research priorities

This post in the Center for Global Health Policy's "Science Speaks" blog examines a report by the PEPFAR Scientific Advisory Board (SAB) that offers six recommended treatment and prevention research priorities to U.S. Global AIDS Ambassador Eric Goosby and the Office of the Global AIDS Coordinator (OGAC) to guide future PEPFAR programs.

19 Nov 2011

Omega-3 linked with reduced joint pain and cognitive side effects of breast cancer therapy

"I know I need this medicine to help lower my chance of cancer recurrence, but it makes my joints ache and stiff. It makes me feel old and I am not sure I can take this medication much longer."

19 Nov 2011

Combo hormone therapy increases risk of breast cancer in women with new-onset tenderness

The debate about using menopausal hormone therapies to relieve symptoms in post-menopausal women has been ongoing. Is the combination therapy of estrogen and progestin better or worse than just giving women estrogen alone? In women who still have a uterus (those who have not had a hysterectomy), progestin counteracts the increased risk of uterus cancer when estrogen is given alone, but at the expense of an increase in breast cancer risk compared to estrogen alone.

19 Nov 2011

HRR1 after 6MW test is a strong predictor of clinical worsening in IPAH patients

Heart rate recovery at one minute after a six-minute walking distance (6MWD) test is highly predictive of clinical worsening and time to clinical worsening in patients with idiopathic pulmonary arterial hypertension (IPAH), according to a new study.

19 Nov 2011

Victory for seniors: Calif. Adult Day Health Care center lawsuit resolved

Senior advocates had sued the state because of Gov. Jerry Brown's plan to shut down the ADHC program to save money.

19 Nov 2011

FDA approves EUSA's orphan drug ERWINAZE for acute lymphoblastic leukemia

EUSA Pharma, a transatlantic specialty pharmaceutical company focused on oncology, oncology supportive care and critical care, today announced that the US Food and Drug Administration (FDA) has approved its orphan drug ERWINAZE (asparaginase Erwinia chrysanthemi) for the treatment of acute lymphoblastic leukemia (ALL) in patients with hypersensitivity to E. coli-derived asparaginase.

19 Nov 2011

MedSolutions introduces ICD Surgery Management Program

MedSolutions, a leading provider of quality-driven medical cost management services, today announced the launch of its Implantable Cardioverter Defibrillator (ICD) Surgery Management Program, which uses evidence-based guidelines to ensure the clinical appropriateness of ICD and CRT-D implantation.

19 Nov 2011

UofL Pediatric Emergency Department fellow wins Willis Wingert Award

University of Louisville Pediatric Emergency Department fellow Alyssa Turner, M.D., has been awarded the Willis Wingert Award for her platform presentation at the American Academy of Pediatrics annual meeting.

19 Nov 2011

CHCWM, Priority Health partner to explore oncology patient-centered medical home

In keeping with society's urgent need for more efficient and effective health care, Priority Health and Cancer and Hematology Centers of West Michigan (CHCWM) have joined forces to explore an innovative oncology patient-centered medical home.

19 Nov 2011

FDA approves EYLEA for treatment of wet Age-related Macular Degeneration

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has approved EYLEA (aflibercept) Injection, known in the scientific literature as VEGF Trap-Eye, for the treatment of patients with neovascular (wet) Age-related Macular Degeneration (AMD) at a recommended dose of 2 milligrams every four weeks for the first 12 weeks, followed by 2 mg every eight weeks.

19 Nov 2011

Therapy News and Research

Study reveals PEA-15 protein can enhance cancer cell proliferation

Despite market constraints, the drug market for key hospital-treated infections will increase: Report

Covidien to acquire BÂRRX Medical

2011 National Report Card on Lung Cancer notes significant change in grade for early detection

PLoS ONE publishes study on darinaparsin, a multivalent chemotherapeutic

Multi-center cabozantinib trial for hormone receptor-positive breast cancer with bone metastases initiated

Adeona to develop and commercialize DNA-based therapeutic for PAH using Intrexon technology

FDA grants HDE marketing approval for BSD-2000 Hyperthermia System to treat cervical cancer

OTS to market and disribute RaySearch's RayStation in South Korea

Convergence commences CNV2197944 multiple ascending dose Phase I study for chronic pain

PEPFAR Scientific Advisory Board report offers six recommended research priorities

Omega-3 linked with reduced joint pain and cognitive side effects of breast cancer therapy

Combo hormone therapy increases risk of breast cancer in women with new-onset tenderness

HRR1 after 6MW test is a strong predictor of clinical worsening in IPAH patients

Victory for seniors: Calif. Adult Day Health Care center lawsuit resolved

FDA approves EUSA's orphan drug ERWINAZE for acute lymphoblastic leukemia

MedSolutions introduces ICD Surgery Management Program

UofL Pediatric Emergency Department fellow wins Willis Wingert Award

CHCWM, Priority Health partner to explore oncology patient-centered medical home

FDA approves EYLEA for treatment of wet Age-related Macular Degeneration

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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