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Monoclonal antibody cancer therapy

The strategy of using monoclonal antibodies for cancer treatment was first described in the late 1970s with the promise that they could be developed into therapies that were highly specific to cancer cells, killing them with few or no side effects.

6 Apr 2009

Locking parasites in host cell could be new way to fight malaria

Researchers at the University of Pennsylvania have discovered that parasites hijack host-cell proteins to ensure their survival and proliferation, suggesting new ways to control the diseases they cause.

6 Apr 2009

New research to study genetics and cell biology of pancreatic cancer

The Georgia Institute of Technology and Saint Joseph's Hospital have joined together to begin the first regional research program to study the genetics and cell biology of pancreatic cancer.

6 Apr 2009

New technique for carrying out gene-expression profiling

A novel technique for carrying out gene-expression profiling is set to challenge the market dominance of the current, widely used methodology, reports Genetic Engineering & Biotechnology News (GEN).

6 Apr 2009

How men and women cope differently with stress traced to genetic differences

Can people's differing reactions to situations of stress be attributed at least in part to genetic differences and do those differences affect men and women in different ways - with the edge seemingly favoring the women? Research conducted at the Hebrew University of Jerusalem would seem to indicate that the answer to both questions is yes.

5 Apr 2009

Discovery of gene that modifies severity of cystic fibrosis lung disease

Researchers at Wake Forest University Baptist Medical Center, and colleagues, have identified a gene that modifies the severity of lung disease in people with cystic fibrosis, a lethal genetic condition.

2 Apr 2009

Molecular test for cancer relapse in UK children

A molecular marker used in America to predict whether children with a form of kidney cancer, called Wilms' tumour, are more likely to relapse than other children, could be useful for UK patients.

2 Apr 2009

Eating a low energy density diet can offset influence of obesity gene

Children who carry a gene strongly associated with obesity could offset its effect by eating a low energy density diet, according to new research from UCL (University College London) and the University of Bristol published in PLoS ONE.

2 Apr 2009

High novelty-seeking and low avoidance of harm contribute to alcohol dependence

Personality factors can influence the development of alcohol dependence (AD).

2 Apr 2009

Drugs that act on 'fasting signal' may curb insulin resistance in obese

A report in the March issue of Cell Metabolism , a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes.

2 Apr 2009

Study looks at vitamin supplements for celiac disease

Coeliac disease is a typical example of a malabsorption syndrome conferring increased risk for various deficiency states, including folate and vitamin B12.

2 Apr 2009

Discovery of gene linked to short-rib polydactyly syndrome

After 12 years of searching, UCLA scientists have tracked down the first known gene mutation responsible for a heartbreaking disorder that kills newborn babies.

1 Apr 2009

The immune system's role in hepatitis C recurrence after liver transplantation

A new study pinpoints certain aspects of the immune system that may play a role in the recurrence and progression of hepatitis C virus (HCV) after liver transplantation.

1 Apr 2009

Possible genetic cause for advanced colorectal cancer in blacks

Researchers have identified a possible genetic cause for increased risk for a more advanced form of colorectal cancer in blacks that leads to shorter survival, according to data published in Clinical Cancer Research , a journal of the American Association for Cancer Research.

1 Apr 2009

A new theory on autism put forward

Scientists at Albert Einstein College of Medicine of Yeshiva University have proposed a sweeping new theory of autism that suggests that the brains of people with autism are structurally normal but dysregulated, meaning symptoms of the disorder might be reversible.

1 Apr 2009

World's first nanofluidic device with complex 3-D surfaces

Researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and Cornell University have capitalized on a process for manufacturing integrated circuits at the nanometer (billionth of a meter) level and used it to develop a method for engineering the first-ever nanoscale fluidic (nanofluidic) device with complex three-dimensional surfaces.

1 Apr 2009