Enzyme News and Research

RSS

Impact of SARS-CoV-2 on oral health

New research examined SARS-CoV-2 and its impact on oral health and suggests that survival against the infection may be partially dependent on such factors.

1 Dec 2021

Role of interferon type I-driven responses associated with disease control in COVID-19

New research suggests that treatment with type I interferons in the early stage of COVID-19 may supress disease progression by limiting SARS-CoV-2 in hosts.

1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Immunotherapies have shown striking clinical benefit in the treatment of many cancers, especially when used in combination with chemotherapy.

30 Nov 2021

Natural COVID-19 infection offers protection from gamma and delta variants of SARS-CoV-2

Natural infection with COVID-19 offered protection from reinfection when the gamma and delta variants predominated, according to a new University of Michigan study that also provides levels of antibodies needed to protect against reinfections.

30 Nov 2021

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Researchers from the University of Michigan investigated the correlation between SARS-CoV-2 infection and the severity of reinfections.

30 Nov 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

Novel influenza vaccine candidate shows promise

Researchers investigate the potential value of a new vaccine candidate for the influenza virus.

29 Nov 2021

Glycosylation and disulfide bonding profile of SARS-CoV-2 spike glycoprotein

Researchers found that virus-like particles produced by co-expression of SARS-CoV-2 S, membrane, envelope, and nucleocapsid proteins contain S glycoproteins, which are modified by complex carbohydrates.

29 Nov 2021

Extended host range for SARS-CoV-2 variants of concern

Researchers used viral pseudotyping to examine whether variants of concern had different host ACE2 receptor usage patterns.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Study finds atazanavir inhibits main SARS-CoV-2 protease

Research shows that ATV has different antiviral activity compared to PAXLOVID™, encouraging further research.

29 Nov 2021

Immunity found 6 months after SARS-CoV-2 infection in children

A new study suggests that infection-induced antibodies persist, providing protection for at least six months.

29 Nov 2021

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Pancreatic cancer is very aggressive and, unfortunately, has a poor prognosis with a 5-year survival of only 5%. Most deaths related to pancreatic cancer are due to metastasis, which occurs when the tumour invades other organs.

29 Nov 2021

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Researchers investigated the immunogenicity of a novel adjuvant comprised of a modified porous silicon microparticle for the SARS-CoV-2 S protein RBD subunit vaccine.

29 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

The introduction and rapid spread of SARS-CoV-2 Gamma in Venezuela

Researchers from the Instituto Venezolano de Investigaciones Científica investigate the introduction of one of the VOCs into Venezuela.

28 Nov 2021

Enzyme News and Research

Impact of SARS-CoV-2 on oral health

Role of interferon type I-driven responses associated with disease control in COVID-19

Novel anti-inflammatory drug target identified by CRISPR

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Natural COVID-19 infection offers protection from gamma and delta variants of SARS-CoV-2

Prior infection with SARS-CoV-2 continues to provide protection from reinfection

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

Novel influenza vaccine candidate shows promise

Glycosylation and disulfide bonding profile of SARS-CoV-2 spike glycoprotein

Extended host range for SARS-CoV-2 variants of concern

Tomosyn protein's key contribution to heterogeneity of neurons revealed

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Study finds atazanavir inhibits main SARS-CoV-2 protease

Immunity found 6 months after SARS-CoV-2 infection in children

Study reveals a previously unknown mechanism for pancreatic cancer metastasis

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

The introduction and rapid spread of SARS-CoV-2 Gamma in Venezuela

Understanding the DNA Damage Response in Innate Immunity eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo