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Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

A protein known to drive nerve cell survival in the brain and spinal cord might also protect failing hearts in children and young adults with Duchenne muscular dystrophy, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions, a premier global exchange of the latest advances in basic cardiovascular science.

2 Aug 2018

Acetyl-L-carnitine chemical in blood connected to depression

A group of researchers from Stanford in collaboration with other universities have found that in humans a low level of acetyl-L-carnitine or L-acetyle carnitine in blood could be a predictor of the duration and severity of depression.

1 Aug 2018

Glaucoma Research Foundation-funded research makes breakthrough in treatment of glaucoma

Glaucoma Research Foundation, a national non-profit organization dedicated to finding a cure for glaucoma, today announced a team of neuroscience researchers, led by Adriana Di Polo, PhD, at University of Montreal, have made a major breakthrough in the treatment of glaucoma.

31 Jul 2018

Alzheimer’s-in-a-dish model made better with microfluidic system

Researchers from Massachusetts have used a microfluidic device to incorporate neuroinflammation into the Alzheimer's-in-a-dish model for drug discovery.

31 Jul 2018

Researchers describe strategy used by Oropouche virus to replicate in human cells

The strategy used by the Oropouche virus to replicate in human cells has been described for the first time by researchers at the University of São Paulo in Brazil and international collaborators in an article published in the journal PLOS Pathogens.

31 Jul 2018

Computational platform predicts how to convert one cell type into another

Researchers have developed a computational platform that predicts how one subtype of cells can be converted into another subtype.

30 Jul 2018

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today that the Committee for Medicinal Products for Human Use has adopted a Positive Opinion recommending marketing authorization of patisiran for the treatment of hereditary transthyretin-mediated amyloidosis in adults with stage 1 or stage 2 polyneuropathy.

27 Jul 2018

Targeting mossy cells may offer new strategy for treating brain disorders

A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.

27 Jul 2018

Researchers investigate how afferent nerves that sprout from the ectopic ear reach the brain

In vertebrates, the inner ear develops from the otic placode, a group of cells found in a specific region on the surface of the growing embryo.

27 Jul 2018

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

After 10 years of research, a Rutgers-led team of scientists has identified two molecules that protect nerve cells after a traumatic brain injury and could lead to new drug treatments.

27 Jul 2018

Experts highlight the need to avoid overdiagnosis and 'excessive' treatment of thyroid cancer

More Americans are being diagnosed with thyroid cancer than ever before--over the past 25 years its incidence has tripled.

26 Jul 2018

Experts describe role of quantitative systems pharmacology in first-in-human clinical trials

Certara, the global leader in model-informed drug development, regulatory science, market access and real-world evidence services, announced today that Clinical Pharmacology & Therapeutics has published its "Letter to the Editor" describing the important role that quantitative systems pharmacology can play in defining dosing criteria for first-in-human clinical trials, together with the European Medicines Agency's response.

26 Jul 2018

Nerve News and Research

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Protein known to drive nerve cell survival may protect children from Duchenne cardiomyopathy

Acetyl-L-carnitine chemical in blood connected to depression

Glaucoma Research Foundation-funded research makes breakthrough in treatment of glaucoma

Alzheimer’s-in-a-dish model made better with microfluidic system

Researchers describe strategy used by Oropouche virus to replicate in human cells

Computational platform predicts how to convert one cell type into another

Alnylam’s patisiran receives positive opinion from CHMP for treating hATTR amyloidosis

Targeting mossy cells may offer new strategy for treating brain disorders

Researchers investigate how afferent nerves that sprout from the ectopic ear reach the brain

Discovery of two molecules could pave way for new drugs to treat traumatic brain injury

Experts highlight the need to avoid overdiagnosis and 'excessive' treatment of thyroid cancer

Experts describe role of quantitative systems pharmacology in first-in-human clinical trials

Cutting-edge laboratory technique recapitulates brain development more accurately than ever

Disrupted transportation routes in nerve cells are main cause of Parkinson's disease

Study gives insights into how better clinical trials can address ‘critically low’ dementia research

Research provides new roadmap for repairing damaged brain cells in multiple sclerosis

Parkinson's therapies being developed may benefit everybody with the disease

Optician’s test could be used to help assess dementia risk

Researchers find link between resilience to dyslexia and gray matter in the brain

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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