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B-cell clones as early markers for chronic lymphocytic leukemia

Testing of blood specimens may detect abnormal white blood cells in patients years before the chronic form of lymphocytic leukemia (CLL) develops, according to research published in the current issue of the New England Journal of Medicine.

22 Feb 2009

States expand newborn screening for life-threatening disorders

Regardless of where they are born in the United States, nearly all newborns now receive mandated screening for many life-threatening disorders, a remarkable public health advance of the last four years, according to a new report issued today by the March of Dimes.

20 Feb 2009

Questions of ethics and quality cloud globalization of clinical trials

Top-tier U.S.-based pharmaceutical companies are moving their clinical trials overseas at warp speed, raising questions about ethics, quality control, and even the scientific value of their findings for people back in the U.S.

20 Feb 2009

Investing in personalized medicine will benefit Canada

Canada has the opportunity to be an international leader in personalized medicine and needs to invest in this area for the health of Canadians and to reap the benefits of job creation, writes Dr. Thomas Hudson in a commentary http://www.cmaj.ca/cgi/rapidpdf/cmaj.1090199 released online today in CMAJ ( Canadian Medical Association Journal ).

20 Feb 2009

Optimizing dosage of blood-thinning drug warfarin

In a large-scale study and an upcoming clinical trial, scientists supported by the National Institutes of Health address one of the trickiest issues in prescribing medicine - how to quickly optimize each patient's dosage of the common blood-thinning drug warfarin.

20 Feb 2009

Researchers study Actin - a globular protein

Actin, a globular protein found in all eukaryotic cells, is a workhorse that varies remarkably little from baker's yeast to the human body.

20 Feb 2009

Mutations in two genes linked to most common brain cancers

Scientists at the Johns Hopkins Kimmel Cancer Center and Duke University Medical Center have linked mutations in two genes, IDH1 and IDH2, to nearly three-quarters of several of the most common types of brain cancers known as gliomas.

20 Feb 2009

Ondansetron shown to be a viable treatment option for opioid addiction

Scientists at Stanford University School of Medicine have discovered that a commonly available non-addictive drug can prevent symptoms of withdrawal from opioids with little likelihood of serious side effects.

18 Feb 2009

Handheld device provides on-the-spot DNA analysis to test tolerance to prescription drugs

A handheld device to predict whether patients will respond adversely to medication is one step closer to the market, thanks to a new partnership.

18 Feb 2009

Genetic ID of marker in lymph nodes may be linked to colorectal cancer recurrence risk

A preliminary report suggests that genetic testing may help identify a marker in lymph nodes that is associated with an increased risk of colorectal cancer recurrence among patients in whom conventional testing indicates that those lymph nodes show no evidence of cancer spread, according to a study in the February 18 issue of JAMA.

18 Feb 2009

Forgotten and lost -- when proteins 'shut down' our brain

Which modules of the tau protein, in neurons of Alzheimer disease patients, may act in a destructive manner were investigated by researchers from the Max Planck Institute for Biophysical Chemistry (Göttingen) and the Max Planck Unit for Structural Molecular Biology (Hamburg) with the help of Nuclear Magnetic Resonance Spectroscopy ( PLoS Biology , February 17, 2009).

18 Feb 2009

Researchers show how immune system reacts to a hepatitis B infection

Researchers at the Helmholtz Centre in Braunschweig demonstrate how the immune system reacts to a hepatitis B infection.

17 Feb 2009

VAP cholesterol test helps find link between a rare gene mutation and heart protection

Using the VAP Cholesterol Test from Atherotech, Inc., University of Maryland researchers have found an association between a rare gene mutation and heart protection.

17 Feb 2009

Discovery of novel genetic markers linked to increased risk of heart attack

An international team of researchers including scientists of Helmholtz Zentrum München has succeeded in identifying new gene variants associated with an increased risk for myocardial infarction (MI), or heart attack.

17 Feb 2009

Braconid parasite wasps have practiced gene therapy for a hundred million years

Braconid parasite wasps and their caterpillar hosts form a unique host-parasite model: the wasps lay their eggs inside the caterpillars and simultaneously inject some viral particles to get around the host's defenses and control its physiology.

17 Feb 2009

About one-fifth of children with hearing loss also have eye disorders

About one-fifth of children with sensorineural hearing loss also have ocular disorders, according to a report in the February issue of Archives of Otolaryngology-Head & Neck Surgery.

17 Feb 2009

Discovery of new mode of how diseases evolve

Researchers of the Michael G. DeGroote Institute for Infectious Disease Research have discovered a new way that bacteria evolve into something that can make you sick.

17 Feb 2009

People with a family history of melanoma may have a greater risk of developing Parkinson's

People with a family history of melanoma may have a greater risk of developing Parkinson's disease, according to a study released today that will be presented at the American Academy of Neurology's 61st Annual Meeting in Seattle, April 25 to May 2, 2009.

17 Feb 2009

Does gene show link between migraine and stroke or heart attacks?

New research looks at whether a gene variant may affect the link between migraine and stroke or heart attacks.

16 Feb 2009

New understanding on how Myc gene promotes cancer

Cancer cells need a lot of nutrients to multiply and survive. While much is understood about how cancer cells use blood sugar to make energy, not much is known about how they get other nutrients.

16 Feb 2009