Biomarker News and Research

RSS

A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

LLNL employs high-performance computing for better understanding of TBI

Since the wars in Afghanistan and Iraq began in 2001, more than 350,000 cases of traumatic brain injury in servicemen and women have been reported to the Department of Defense.

3 Jul 2018

Researchers find elevated biomarkers of brain injury after high-acceleration head impacts

Researchers from the University of Michigan found that serum levels of two biomarkers of traumatic brain injury, tau and ubiquitin C-terminal hydrolase L1, are elevated following high-acceleration head impacts, even when there is no clinical diagnosis of concussion.

3 Jul 2018

Increase in marker of inflammation from mid to late life linked with dementia

Researchers at Johns Hopkins have added to evidence that rising and chronic inflammation as measured by a biomarker in the blood in middle and late age are linked to visible structural changes in the brains of people with poor cognition and dementia.

2 Jul 2018

Novel sensing technology enables live and super-sensitive monitoring of biomarkers

The human body is an extremely complex molecular machine, the details of which can be followed through certain substances; so-called biomarkers.

2 Jul 2018

New biomarker paves way for personalized bladder cancer treatments

Researchers have identified a potential new target for the treatment of a particularly aggressive form of bladder cancer, in the form of microRNA.

2 Jul 2018

Researchers find new marker for better prognosis in gastric and esophageal cancer

Tumors that develop at the transition of the stomach to the esophagus, so-called adenocarcinomas of the gastroesophageal transition, are still difficult to treat and the chances of recovery are still low.

2 Jul 2018

New Rekovelle analysis shows AMH is robust predictor of ovarian response to fertility treatment

Ferring Pharmaceuticals announced today a new analysis of data from the Phase 3 ESTHER-1 trial showing that natural variations in anti-Müllerian hormone levels during and between a woman's menstrual cycle have no clinically relevant impact on ovarian response when using AMH to dose Rekovelle for ovarian stimulation.

2 Jul 2018

Research shows why new cancer therapies fail to work on some patients

University of Otago research provides insights into an underlying mechanism that could explain why new cancer therapies to help treat metastatic melanoma do not always work on patients, paving the way for predicting which patients will benefit from certain drugs.

30 Jun 2018

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Researchers at Indiana University have found early evidence that tiny snippets of genetic material called microRNA may help with early detection of conditions such as Alzheimer's disease.

29 Jun 2018

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

A DNA-level biomarker (MGMT promoter methylation) can be used to help predict survival outcomes in patients with high-risk, low-grade gliomas, according to a new study conducted through the NRG Oncology/RTOG collaborative clinical trials group and led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

28 Jun 2018

DNA methylation predicts survival outcome in patients with glioma

A new study has shown that survival rates among patients with glioma double if the tumor carries a methylated MGMT gene.

28 Jun 2018

MDxHealth releases positive data demonstrating value of SelectMDx test for prostate cancer patients

MDxHealth SA, today announced the publication of positive data demonstrating the value of the SelectMDx liquid biopsy test for Prostate Cancer in guiding patient management for men being considered for multiparametric MRI and the clinical utility in guiding biopsy decisions in real-world clinical practice.

From MDxHealth 28 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research.

25 Jun 2018

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer.

25 Jun 2018

Nightingale Health to analyze biomarker profiles of 500,000 blood samples from UK Biobank

Comprehensive metabolic biomarker profiles of the world's largest health database to be analyzed in 30 months.

22 Jun 2018

Study: Measuring levels of ethyl sulphate in hair can help assess alcohol consumption

A new Drug Testing & Analysis study reveals that measuring levels of ethyl sulphate, a metabolite of ethanol, in the hair can be used to assess alcohol consumption.

20 Jun 2018

Improving the quality of biomedical research samples

IBBL (Integrated BioBank of Luxembourg) announces the launch of Findmyassay.com, a new online tool allowing scientists to check the quality of their biological samples and improve the reproducibility of their biomedical research.

19 Jun 2018

MAARA to celebrate its 50th anniversary with lecture titled 'The Future of Asthma'

50 years of pioneering asthma research which has benefited patients and sufferers throughout the UK will be celebrated at an event hosted by the University of Leicester on Wednesday 20 June.

19 Jun 2018

Studies provide insight into molecular changes prior to onset of arthritis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) provide insight into molecular changes prior to the onset of arthritis which could inform future novel diagnostics and early therapeutic interventions.

18 Jun 2018

Biomarker News and Research

Further Reading

LLNL employs high-performance computing for better understanding of TBI

Researchers find elevated biomarkers of brain injury after high-acceleration head impacts

Increase in marker of inflammation from mid to late life linked with dementia

Novel sensing technology enables live and super-sensitive monitoring of biomarkers

New biomarker paves way for personalized bladder cancer treatments

Researchers find new marker for better prognosis in gastric and esophageal cancer

New Rekovelle analysis shows AMH is robust predictor of ovarian response to fertility treatment

Research shows why new cancer therapies fail to work on some patients

Tiny snippets of genetic material may help with early detection of Alzheimer's disease

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

DNA methylation predicts survival outcome in patients with glioma

MDxHealth releases positive data demonstrating value of SelectMDx test for prostate cancer patients

Researchers discover immune profile for effective cancer immunotherapy

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Nightingale Health to analyze biomarker profiles of 500,000 blood samples from UK Biobank

Study: Measuring levels of ethyl sulphate in hair can help assess alcohol consumption

Improving the quality of biomedical research samples

MAARA to celebrate its 50th anniversary with lecture titled 'The Future of Asthma'

Studies provide insight into molecular changes prior to onset of arthritis

Event guide: World Clinical Biomarkers & CDx Summit Japan eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo