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Cholera variants need to be monitored closely to prevent outbreaks, scientists urge

Cholera variants are constantly evolving and need to be monitored closely to prevent outbreaks, say researchers.

20 Jul 2022

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Genes and lifestyle factors together play a role in stroke risk. However, even for people at high risk for stroke, adopting a healthy cardiovascular lifestyle may significantly lower the risk of stroke in their lifetime, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

20 Jul 2022

Researchers report the detection of viral mutations associated with drug resistance in patients treated with REGEN-COV and sotrovimab

Researchers reported mutations in SARS-CoV-2 Delta and Omicron variants of concern infection cases treated with neutralizing monoclonal antibodies.

20 Jul 2022

Study shows Omicron BA.4/5 infection triggers highly cross-reactive neutralizing antibodies

Researchers compared the levels of cross-reactive neutralizing antibodies elicited by SARS-CoV-2 Omicron BA.4 and BA.1 infections.

20 Jul 2022

Machine learning models help forecast immunotherapy response from gut microbiomes

A new research paper was published in Oncotarget on July 19, 2022, entitled, "Predicting cancer immunotherapy response from gut microbiomes using machine learning models."

20 Jul 2022

Genes underlying cigarette smoking linked to the perception of pain and response to food

Have you ever wondered why one person can smoke cigarettes for a year and easily quit, while another person will become addicted for life? Why can't some people help themselves from abusing alcohol and others can take it or leave it?

20 Jul 2022

New way to test vaccines may be as rigorous and stringent as exposure to field strains of malaria

Malaria is the deadliest mosquito-borne parasitic infection of humans. In 2021, after a century of research, the World Health Organization (WHO) approved the world's first malaria vaccine.

20 Jul 2022

Study determines the reason behind the failure of IVF embryos

In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia University Vagelos College of Physicians and Surgeons have found that most of these mistakes are due to spontaneous errors in DNA replication in the earliest phase of cell division.

20 Jul 2022

Non-coding 'junk' DNA could potentially contribute to the development of cancer

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer.

19 Jul 2022

Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

A new study has pointed out that Molnupiravir treatment increases the ratio of transition to transversion mutations in COVID-19 patients and that the treatment does not appear to induce resistance mutations in the SARS-CoV-2 genome.

19 Jul 2022

Study shows how a critical Lassa virus protein drives infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15 percent in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine or antiviral to protect against Lassa virus.

19 Jul 2022

Elephant genes could offer new clues to preventing cancer development

Scientists modeling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions - with implications for cancer treatments in humans.

19 Jul 2022

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia.

19 Jul 2022

Researchers report genomic profiling from more than 110,000 tumors

Researchers analyzed data from the latest public release of the GENIE project of the American Association for Cancer Research.

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Influence of chr12q24.13 domain on COVID-19 severity

Researchers evaluated the probable impact of the chr12q24.13 domain on the outcomes of laboratory-validated SARS-CoV-2 infection.

19 Jul 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Scientists manipulate good bacteria using CRISPR systems

New North Carolina State University research shows progress in gathering information on an important – yet difficult to characterize – human gut bacterium called Bifidobacterium, which is used in many probiotics that help maintain healthy microbiomes.

19 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

Genome News and Research

Cholera variants need to be monitored closely to prevent outbreaks, scientists urge

Adopting a healthy cardiovascular lifestyle may lower stroke risk

Researchers report the detection of viral mutations associated with drug resistance in patients treated with REGEN-COV and sotrovimab

Study shows Omicron BA.4/5 infection triggers highly cross-reactive neutralizing antibodies

Machine learning models help forecast immunotherapy response from gut microbiomes

Genes underlying cigarette smoking linked to the perception of pain and response to food

New way to test vaccines may be as rigorous and stringent as exposure to field strains of malaria

Study determines the reason behind the failure of IVF embryos

Non-coding 'junk' DNA could potentially contribute to the development of cancer

Molnupiravir does not induce resistance mutations in SARS-CoV-2 genome

Study shows how a critical Lassa virus protein drives infection

Elephant genes could offer new clues to preventing cancer development

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers report genomic profiling from more than 110,000 tumors

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Influence of chr12q24.13 domain on COVID-19 severity

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

Scientists manipulate good bacteria using CRISPR systems

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Genetics & Genomics - Second Edition eBook

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The Critical Role of Sample Storage in Drug Discovery and Development

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